Results 151 to 160 of about 659,302 (281)

AI-Enhanced System for Diabetic Foot Ulcer Localization and Classification Using Multi-Scale Neural CNN Model. [PDF]

Health Sci Rep
Nur-A-Alam M, Anwar Hussen Wadud M, Nasir MK, Uddin KMM.   +3 more
europepmc   +1 more source

Unraveling Bone‐Skin Crosstalk Enables miRNA Nanoformulation for Cutaneous Neurovascular Reconstruction in Diabetic Mice

Advanced Science, Volume 13, Issue 55, 5 October 2026.
This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen, Hongdou Shen, Weiyue Wu, Zhuoying Jiang, Bin Liu, Yansi Xian, Rui Peng, An Yan, Yu Ben, Yong Shi, Xiang Chen, Baosheng Guo, Qing Jiang, Weijun Wang, Pingqiang Cai   +14 more
wiley   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, Volume 2, Issue 5, October 2026.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Wearable Technologies for Diabetic Foot Ulcer Monitoring and Risk Prediction: Systematic Review. [PDF]

JMIR Diabetes
Ehtemam H, Salehinejad S, Robbins D, Sanaei A, Shirvani H, Sadeghi-Esfahlani S.   +5 more
europepmc   +1 more source

First‐in‐human, phase I, randomized, safety, pharmacokinetic, food‐effect and pharmacodynamic study of a tyrosine kinase 2/Janus kinase 1 inhibitor, SDC‐1801

British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3513-3526, October 2026.
Aim The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), food‐effect (FE) and pharmacodynamics (PD) of an oral tyrosine kinase‐2 (TYK2)/Janus kinase‐1 (JAK1) inhibitor, SDC‐1801, in healthy adult participants. Methods This first‐in‐human study randomized 95 male and female participants.
Chris Brearley, Sam Francis, John Reader, Judi Proctor   +3 more
wiley   +1 more source

Shengji ointment accelerates diabetic foot ulcer wound healing by regulating inflammatory microenvironment. [PDF]

Front Pharmacol
Dai R, Guo J, Jing J, Zhang Y, Liu H, Zhang Z, Zhu C.   +6 more
europepmc   +1 more source

Rare Case of Necrotizing Fasciitis With Polyarteritis Nodosa in a Multi‐Comorbid Patient

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Necrotizing fasciitis can mimic cellulitis in immunocompromised patients, delaying diagnosis. This case highlights the importance of early clinical suspicion despite low LRINEC score. Prompt surgical intervention, appropriate antibiotics, and recognition of underlying conditions like polyarteritis nodosa are critical to reduce morbidity and ...
Syed Muhammed Salman Hassan, Sarim Hassan Shahab, Masroor Raza, Salman Saleem, Muhammad Fahad Hussain, Fazal Habib   +5 more
wiley   +1 more source

Impact of music therapy on diabetes distress and bio-physiological parameters in patients with diabetic foot ulcer. [PDF]

J Educ Health Promot
Ullas A, Adhikari P, Leena KC, Subramaniam V.   +3 more
europepmc   +1 more source

Harnessing Terminalia arjuna in Next Generation Phytomedicine: Cutting Edge Nutraceutical Trends Shaping Food and Health

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
This graphical abstract illustrates the complete translational pipeline of Terminalia arjuna in modern phytomedicine and functional food development. It is rich in key bioactive compounds like arjunolic acid, arjungenin, flavonoids, and tannins which serve as the foundation for the plant's versatile medicinal uses and offers broad therapeutic benefits ...
Ishani Banerjee, Fahika Nazeerulla, Manash Kumar Paul, Sujit Kumar Bhutia, Deblina Basu, Subhadip Mukhopadhyay   +5 more
wiley   +1 more source

How Do Poverty, Insurance, and Government Assistance Impact Diabetic Foot Ulcer Outcomes? A Scoping Review. [PDF]

Diabetes Metab Res Rev
LaMantia JN, McClain D, Daniele A, Conte MS, Fayfman M, Oropallo A, Schechter MC, Spino C, Ye W, Iannuzzi JC, Brennan MB.   +10 more
europepmc   +1 more source