Results 191 to 200 of about 44,427 (283)

Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai   +3 more
wiley   +1 more source

Screening and Functional Analysis of tsRNAs Associated with Diabetic Foot Ulcer Tissues. [PDF]

open access: yesBiomedicines
He X   +8 more
europepmc   +1 more source

Hydrogen‐Enriched Hyaluronic Acid Dressing Ameliorates Diabetic Foot Ulcer via Promoting Mitophagy

open access: yesJournal of Diabetes, Volume 18, Issue 4, April 2026.
The combination of VSD and hydrogen‐rich saline is used to treat diabetic foot ulcers. In vitro and in vivo studies reveal that hydrogen‐enrich hyaluronic acid dressings enhance skin fibroblast repair ability by regulating mitophagy via the SIRT3 and its downstream signaling pathways, ultimately accelerating wound healing in diabetic foot ulcers ...
Ziyu Xu   +8 more
wiley   +1 more source

Osteomyelitis and Its Main Determinants in Patients With Diabetic Foot Ulcer: A Cross-Sectional Study. [PDF]

open access: yesHealth Sci Rep
Bolandi S   +5 more
europepmc   +1 more source

Healing Steps on Country—Exploring Care Pathways for Aboriginal People in the Kimberley With Diabetes‐Related Foot Disease

open access: yesAustralian Journal of Rural Health, Volume 34, Issue 2, April 2026.
ABSTRACT Objective This project aimed to document the experiences of Aboriginal people living in the Kimberley region who have experienced diabetes‐related foot disease (DFD) so that service delivery can be optimised. Setting The Kimberley region, Western Australia. Participants Aboriginal People in the Kimberley with DFD.
Sophie Moustaka   +7 more
wiley   +1 more source

Enhancing diabetic foot osteomyelitis diagnosis with metagenomics next‐generation sequencing, proof of concept

open access: yesDiabetic Medicine, Volume 43, Issue 4, April 2026.
The use of mNGS with the MinION tool clearly provides a significant advantage compared to routine culture by identifying a higher diversity of pathogens in diabetic foot osteomyelitis. It also highlights the value of this method in clinical decision making, despite the technical challenges inherent in metagenomic sequencing.
Madjid Morsli   +8 more
wiley   +1 more source

Beyond the wound: A scoping review of the psychosocial impact of diabetes‐related foot ulcers

open access: yesDiabetic Medicine, Volume 43, Issue 4, April 2026.
Living with a DFU is a complex and ongoing journey. From initial onset through active management and long‐term living, individuals can experience a substantial psychosocial burden, including emotional distress, treatment burden and challenges with self‐management.
Michelle Hanlon   +9 more
wiley   +1 more source

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