Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai +3 more
wiley +1 more source
A cross-sectional clinical analysis on diabetic foot ulcer and associated risk management.
Shamsudeen MA +2 more
europepmc +1 more source
Screening and Functional Analysis of tsRNAs Associated with Diabetic Foot Ulcer Tissues. [PDF]
He X +8 more
europepmc +1 more source
Hydrogen‐Enriched Hyaluronic Acid Dressing Ameliorates Diabetic Foot Ulcer via Promoting Mitophagy
The combination of VSD and hydrogen‐rich saline is used to treat diabetic foot ulcers. In vitro and in vivo studies reveal that hydrogen‐enrich hyaluronic acid dressings enhance skin fibroblast repair ability by regulating mitophagy via the SIRT3 and its downstream signaling pathways, ultimately accelerating wound healing in diabetic foot ulcers ...
Ziyu Xu +8 more
wiley +1 more source
Osteomyelitis and Its Main Determinants in Patients With Diabetic Foot Ulcer: A Cross-Sectional Study. [PDF]
Bolandi S +5 more
europepmc +1 more source
ABSTRACT Objective This project aimed to document the experiences of Aboriginal people living in the Kimberley region who have experienced diabetes‐related foot disease (DFD) so that service delivery can be optimised. Setting The Kimberley region, Western Australia. Participants Aboriginal People in the Kimberley with DFD.
Sophie Moustaka +7 more
wiley +1 more source
Procalcitonin and Diabetic Foot Ulcer Infections: A Meta-Analysis. [PDF]
Wang W, Zhou P, Nie X, Hua Q.
europepmc +1 more source
The use of mNGS with the MinION tool clearly provides a significant advantage compared to routine culture by identifying a higher diversity of pathogens in diabetic foot osteomyelitis. It also highlights the value of this method in clinical decision making, despite the technical challenges inherent in metagenomic sequencing.
Madjid Morsli +8 more
wiley +1 more source
Correction: Association of the neutrophil-to-lymphocyte ratio with sudden cardiac death in the patients with diabetic foot ulcer. [PDF]
Chen Y +5 more
europepmc +1 more source
Beyond the wound: A scoping review of the psychosocial impact of diabetes‐related foot ulcers
Living with a DFU is a complex and ongoing journey. From initial onset through active management and long‐term living, individuals can experience a substantial psychosocial burden, including emotional distress, treatment burden and challenges with self‐management.
Michelle Hanlon +9 more
wiley +1 more source

