Results 51 to 60 of about 28,705 (309)

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Risk factors associated with the recurrence of diabetic foot ulcers: A meta-analysis.

PLoS ONE
AimsDiabetic foot ulcers have caused significant medical, economic and social consequences for patients, families and society. With appropriate treatment, many diabetic foot ulcers can heal, temporarily avoiding possible amputation.
Chunmei Lin, Jianqing Tian, Zhijun Zhang, Caiyu Zheng, Jinhao Liu   +4 more
doaj   +1 more source

Frequency of Chronic Kidney Disease in Type 2 Diabetic Patients Presenting with Diabetic Foot Ulcer

Pakistan Journal of Medicine and Dentistry, 2020
Background: Recent evidence states that about a quarter of all diabetic patients will experience an ulcer on foot at some point in their lifetime and 15-25% of these will require foot amputation.
Sarwat Ashraf, Asif Aziz, Mir Tahir Hussain Talpur, Sagheer Ahmed Solangi, Khalil Ullah Shabir, Ghazala Usman, Moiz Ahmed, Kiran Abbas   +7 more
doaj   +1 more source

Seta‐Inspired Mechano‐Intelligent Janus Bandage with Coordinated Adhesion–Contraction for Minimizing Scarring

Advanced Materials, EarlyView.
We developed a bioinspired mechano‐intelligent Janus bandage (MIB) with a hydrophobic flat exterior and a hydrophilic interior featuring gecko‐mimicking wedged microstructures, fabricated via micromolding and anisotropic plasma treatment. The MIB dynamically synchronizes adhesion and contraction, enabling precise force modulation.
Di Suo, Yuhe Yang, Shuai Zhao, Ho‐Pan Bei, Avery Chik‐Him Lam, Wei‐Qiang Tan, Kenneth Kak‐yuen Wong, Xin Zhao   +7 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery

Advanced Science, EarlyView.
A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo, Yuanyuan Meng, Qixiang Gui, Xi‐Tao Yang, Yong Fan, Xiaodong Zhu   +5 more
wiley   +1 more source

Electrical‐Stimulation Hydrogel Electronic Skin for Sustainable Hybrid Biomechanical–Electromagnetic Energy Harvesting and Accelerating Wound Healing

Advanced Science, EarlyView.
A hybrid biomechanical–electromagnetic energy‐harvesting e‐skin is developed using a gelatin‐based outer matrix with a zwitterionic conductive inner layer. The e‐skin autonomously generates stable electrical stimulation from daily body motion and ambient electronics, enabling significantly enhanced wound healing bothin vitro and in vivo.
Syun‐Hong Chou, Ming‐Han Lu, Wei‐Chen Peng, Wei‐Chun Yang, Pei‐Yi Liu, Yu‐Hsuan Yang, Yi‐Lin Huang, Cheng‐Hung Tsai, Ting‐Yu Yang, Xuan Zhang, Zhi‐Xian Yan, Ying‐Chih Lai, San‐Yuan Chen   +12 more
wiley   +1 more source

Exploiting Temperature Effects for Robust Control and Reference Circuits Using Thin‐Film Contact‐Controlled Transistors

Advanced Electronic Materials, EarlyView.
Compact circuits based on contact‐controlled transistors are well‐suited to unsupervised thermal management, sensitive temperature measurement, or temperature‐stable current references. Demonstrated on flexible microcrystalline silicon and supported by simulation, the approach does not require supply voltage regulation, remains manufacturable across ...
Eva Bestelink, Jean‐Charles Fustec, Olivier de Sagazan, Rogier Fransen, George Bairaktatis, Emmanuel Jacques, Radu A. Sporea   +6 more
wiley   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Cooptimized Sensing and Sole Mechanics Enable Embodied‐Intelligence Design of User‐Specific Smart Footwear

Advanced Intelligent Systems, EarlyView.
An embodied codesign framework for smart footwear is presented, jointly tuning lattice mechanics and sensing for personalized plantar pressure monitoring. By integrating pneumatic sensing within 3D‐printed lattice soles, the system achieves accurate real‐time centre‐of‐pressure tracking with reduced sensor count and energy demand, demonstrating how ...
Fengyu Zhong, Marco Pontin, Amy Zavatsky, Perla Maiolino   +3 more
wiley   +1 more source