Results 101 to 110 of about 456,397 (279)

Real‐world observational study evaluating metabolic and kidney outcomes in patients living with chronic kidney disease and type 2 diabetes mellitus with obesity prescribed tirzepatide

Diabetic Medicine, EarlyView.
Abstract Background Obesity and type 2 diabetes mellitus (T2DM) accelerate chronic kidney disease (CKD) progression. Tirzepatide, a dual glucagon‐like peptide‐1 (GLP‐1) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonist, has demonstrated metabolic and potential renoprotective benefits in clinical trials.
Jack E. Carruthers, Xi Yan Ooi, Dawn Goodall, Jo Reed, Rachna Bedi, Adrian McGrath, Michelle Willicombe, Parizad Avari, Andrew H. Frankel   +8 more
wiley   +1 more source

Implementation and Phase 1 evaluation outcomes of the NHS England National Diabetes Transition and Young Adult Pilot Programme (2022–2026)

Diabetic Medicine, EarlyView.
Abstract Aims This programme was a 4‐year, centrally commissioned endeavour to gather evidence of strategies to implement a model service specification in 15 pilot sites and improve outcomes in 16‐ to 25‐year‐olds with diabetes. Methods Retrospective cohort study evaluating the quantitative and qualitative impact of implementing the model service ...
Reza Zaidi, Fulya Mehta, Partha Kar, Jonathan Valabhji, Verity Hawkes, Lucy Holmes, Karen Kennedy, Sheena Dungey, Mo Jaffer Ismail   +8 more
wiley   +1 more source

Acute Kidney Injury in Children with Diabetic Ketoacidosis

مجلة الكوفة الطبية
Backgrounds and Objectives: Diabetic ketoacidosis is frequent in type I diabetic children, and as acute kidney injury has a well-known morbidity, this study aims to determine the frequency and associated factors of acute kidney injury in these children.
Anfal MB. Hamoodi, Wid Abdul Razak Asif, Bushra Jalil Salih, Tala Anwar Al Awqati   +3 more
doaj   +1 more source

Diagnosis and Management of Adult Type 1 Diabetes Mellitus: Systematic Reviews of Biomarkers, Insulin Regimens and Insulin Delivery Devices Highlighting Evidence Gaps in Emergency and Humanitarian Settings

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Supporting the World Health Organization's (WHO) 2021 Global Diabetes Compact's goals, we conducted three systematic reviews on type 1 diabetes (T1D) in adults concerning (1) diagnostic biomarkers, (2) insulin regimens and (3) insulin delivery devices, focusing on emergency and humanitarian settings.
Niyati Patwa, Alexandria Bennett, Nicole Shaver, Lama Dahroug, Becky Skidmore, Shannon E. Kelly, George Wells, Andrea C. Tricco, Heather Lochnan, Julian Little, Melissa Brouwers   +10 more
wiley   +1 more source

Diabetic ketoacidosis knowledge in type 1 diabetes: a Brazilian perspective

Archives of Endocrinology and Metabolism
Objective: To evaluate the factors associated with knowledge of diabetic ketoacidosis among individuals with type 1 diabetes mellitus and to analyze how sociodemographic, clinical, and healthcare access variables influence understanding of the condition ...
Renan Bruno Faria Pisani, Virgínia Valiate Gonzalez, Bruna Rambo Witte, Taylane Guimarães Gonçalves, Lohane Alves Santiago, Adalgiza Mafra Moreno, Rodrigo de Azeredo Siqueira   +6 more
doaj   +1 more source

GLP‐1–Based Therapy in Type 1 Diabetes: Balancing Efficacy, Safety, and Patient Selection

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To critically examine the evolving evidence on glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and the dual glucose‐dependent insulinotropic polypeptide (GIP)/GLP‐1 receptor agonist tirzepatide as adjuncts to insulin therapy in type 1 diabetes (T1D), with particular emphasis on their benefit–risk balance in individuals with ...
Thales Rossatto, Ricardo de Andrade Oliveira, Andréia Machado Cardoso   +2 more
wiley   +1 more source

Frequency of Diabetic Ketoacidosis and Severe Hypoglycemia in Children with Type 1 Diabetes

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2022
Background and Objective: Diabetic ketoacidosis and severe hypoglycemia are common and recurrent acute complications of type 1 diabetes and are associated with high mortality and morbidity. The aim of this study was to determine the frequency of diabetic
A Homaei, F Saffari, E Parsarad, ZS Mohammadi   +3 more
doaj  

Cerebral infarction associated with transient visual loss in child with diabetic ketoacidosis

, 2011
BACKGROUND: Diabetic ketoacidosis is a metabolic disorder caused by insulin deficiency and is the most important cause of mortality and morbidity in children with Type 1 diabetes mellitus. Acute neurological complications related to diabetic ketoacidosis
Hwang, JS, H. S. Lee, J. S. Hwang, Lee, HS   +3 more
core   +1 more source

Atypical Feature of Diabetic Ketoacidosis with Low or Normal Plasma Glucose: a Narrative Review [PDF]

, 2019
Context: Diabetic Ketoacidosis (DKA) is a well-known emergency in diabetic patients. In a subgroup of patients ketoacidosis is present but is not accompanied by the marked hyperglycemia considered part of the diagnostic criteria for DKA. This is known as
Niroomand, Mahtab, Jalili, Mohammad
core   +1 more source

The Smart MDI System in People With Type 1 Diabetes and High HBA1C: A Randomized Controlled Trial Demonstrating That Response to Alerts Drives Outcomes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims The aim was to assess the efficacy and safety of the smart multiple daily injections (MDI) system versus MDI plus continuous glucose monitor (CGM) in people with Type 1 diabetes and HbA1c ≥ 8%. Material and Methods After a 3‐week run‐in, 143 participants were randomized to Smart MDI or MDI + CGM.
Laurent Crenier, Martin Haluzik, Marcus Lind, Pieter Gillard, Regis P. Radermecker, Angela Girelli, Jens Kroeger, Valeria Cosma, Francesco Giorgino, Charles Thivolet, Peter Adolfsson, Tobias Wiesner, Emmanuel Sonnet, Christophe de Block, Torben Biester, Helene Hanaire, Fabio di Piazza, Fabiona Hoevelaken, Renee Tillie, Tim van den Heuvel, Shannon Edd, Ohad Cohen   +21 more
wiley   +1 more source