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Disease-a-Month
Diabetic kidney disease is a leading cause of kidney failure worldwide and is easily detectable with screening examination. Diabetes causes hyperfiltration and activation of the renin-angiotensin aldosterone system by hemodynamic changes within the nephron, which perpetuates damaging physiology.
Anna, Gaddy +5 more
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Diabetic kidney disease is a leading cause of kidney failure worldwide and is easily detectable with screening examination. Diabetes causes hyperfiltration and activation of the renin-angiotensin aldosterone system by hemodynamic changes within the nephron, which perpetuates damaging physiology.
Anna, Gaddy +5 more
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KCa3.1 in diabetic kidney disease
Current Opinion in Nephrology & Hypertension, 2021Purpose of review Diabetic kidney disease (DKD) is a significant health concern. Innovative strategies to prevent or limit the progression of DKD are urgently needed due to the limitation of existing treatments. KCa3.1, a potassium channel, is involved in a range of biological processes from cell survival to cell death.
Chunling, Huang +2 more
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Diabetic Kidney Disease: Chronic Kidney Disease and Diabetes
Diabetes Spectrum, 2008The traditional clinical hallmark of chronic kidney disease (CKD) in diabetic microvascular disease of the kidney has been overt proteinuria; once manifest, diabetic nephropathy was considered apparent. The term “nephropathy” classically was associated with foamy urine, hypertension, and renal edema formation attributable to sodium retention and ...
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Chronic kidney disease and diabetes
Maturitas, 2012Chronic kidney disease has a significant worldwide prevalence affecting 7.2% of the global adult population with the number dramatically increasing in the elderly. Although the causes are various, diabetes is the most common cause of CKD in the United States and an increasing cause of the same worldwide. Therefore, we chose to focus on diabetic chronic
Ronald, Pyram +3 more
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Aldosterone and diabetic kidney disease
Current Diabetes Reports, 2009Aldosterone plays an important role in salt and water homeostasis and blood pressure control through the classical mineralocorticoid receptor. However, recent findings of the mineralocorticoid receptor in nonepithelial tissues suggest that aldosterone may have additional functions.
Young Sun, Kang, Dae Ryong, Cha
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Diabetes and chronic kidney disease
Disease-a-Month, 2015The total number of patients with diabetes mellitus (DM) has been steadily increasing in most countries, including the United States. DM has been identified as a contributing factor in a number of conditions, most notably cardiovascular disease, retinal disease, and renal disease.
Andrew, Kowalski +2 more
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Pentoxifylline for diabetic kidney disease
Cochrane Database of Systematic Reviews, 2012Diabetic kidney disease (DKD) is associated with increased morbidity and mortality, mostly relating to cardiovascular complications. The relevance of inflammation in the pathogenesis of DKD has been investigated in recent years, and it has been shown that inflammatory markers are higher in people with DKD compared with the wider population ...
Dan, Shan +5 more
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Diabetic Kidney Disease and Hypertension
Experimental and Clinical Endocrinology & Diabetes, 2015Achieving blood pressure (BP) goals is an essential goal for both primary and secondary prevention of diabetic kidney disease (DKD). Even though there is universal agreement about the importance of controlling BP, there are many issues about many aspects of hypertension management for DKD patients.
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Diabetes and Chronic Kidney Disease
JAMAThis JAMA Insights discusses the evaluation and treatment of chronic kidney disease in patients with type 1 and type 2 diabetes.
Christine P, Limonte +2 more
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Inflammation in Diabetic Kidney Disease
Nephron, 2018<b><i>Background:</i></b> Diabetes is a growing public health problem. Diabetic kidney disease (DKD) is the most prevalent chronic renal disease and the major cause of end-stage renal failure worldwide, predominantly due to the increase of Type 2 diabetes associated with obesity.
Rosa E, Pérez-Morales +5 more
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