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Metabolomics as a tool for the early diagnosis and prognosis of diabetic kidney disease
Medicinal research reviews (Print), 2022Diabetic kidney disease (DKD) is one of the most prevalent comorbidities of diabetes mellitus and the leading cause of the end‐stage renal disease (ESRD).
Pedro R Pereira +5 more
semanticscholar +1 more source
2019
Abstract Diabetic kidney disease (DKD) is the most common cause of ESRD in USA as well as in the world. The incidence and the prevalence of DKD have been increasing regardless of current intervention. The pathology of DKD is characterized by accumulation of extracellular matrix in GBM and mesangial area.
Radica Z. Alicic +2 more
+6 more sources
Abstract Diabetic kidney disease (DKD) is the most common cause of ESRD in USA as well as in the world. The incidence and the prevalence of DKD have been increasing regardless of current intervention. The pathology of DKD is characterized by accumulation of extracellular matrix in GBM and mesangial area.
Radica Z. Alicic +2 more
+6 more sources
Normoalbuminuric diabetic kidney disease
Frontiers of Medicine, 2017Diabetic kidney disease (DKD) is one of the primary causes of end-stage renal disease (ESRD). Early diagnosis is very important in preventing the development of DKD. Urinary albumin excretion rate (UAER) and glomerular filtration rate (GFR) are widely accepted as criteria for the diagnosis and clinical grading of DKD, and microalbuminuria has been ...
Chao, Chen +7 more
openaire +2 more sources
Cardiovascular Disease and Diabetic Kidney Disease
Seminars in Nephrology, 2018Diabetic kidney disease commonly is associated with an increased risk of cardiovascular disease. There are traditional common risk factors for both conditions including hypertension and poor glycemic control. However, it is likely that there are other pathophysiological mechanisms that explain the clinical phenomenon of increased cardiovascular disease
Muhammad, Maqbool +2 more
openaire +2 more sources
Diabetic Kidney Disease: Chronic Kidney Disease and Diabetes
Diabetes Spectrum, 2008The traditional clinical hallmark of chronic kidney disease (CKD) in diabetic microvascular disease of the kidney has been overt proteinuria; once manifest, diabetic nephropathy was considered apparent. The term “nephropathy” classically was associated with foamy urine, hypertension, and renal edema formation attributable to sodium retention and ...
openaire +1 more source
Microparticles in diabetic kidney disease
Clinica Chimica Acta, 2022Diabetic kidney disease (DKD) is the most common cause of renal failure and a major contributor to the socioeconomic burden in chronic kidney disease (CKD) patients worldwide. The pathogenesis of DKD involves all the structures in the nephron, and it is indicated by proteinuria, hypertension, and progressive decline in renal function, leading to ...
Sushma Thimmaiah, Kanakalakshmi +5 more
openaire +2 more sources
2012
A 35-year-old man with a 12 year history of type 1 diabetes presents with a new onset lower extremity edema and proteinuria. The patient had noted a 25 lb weight gain in a period of 8 weeks and had experienced headaches and blurry vision. He did carry a diagnosis of proliferative diabetic retinopathy in the past and also had had diabetic neuropathy on ...
Raimund H. Pichler +3 more
openaire +2 more sources
A 35-year-old man with a 12 year history of type 1 diabetes presents with a new onset lower extremity edema and proteinuria. The patient had noted a 25 lb weight gain in a period of 8 weeks and had experienced headaches and blurry vision. He did carry a diagnosis of proliferative diabetic retinopathy in the past and also had had diabetic neuropathy on ...
Raimund H. Pichler +3 more
openaire +2 more sources
Pathophysiology of diabetic kidney disease: impact of SGLT2 inhibitors
Nature Reviews Nephrology, 2021R. DeFronzo, W. B. Reeves, Alaa S. Awad
semanticscholar +1 more source
Targeting inflammation to treat diabetic kidney disease: the road to 2030.
Kidney International, 2022S. Rayego‐Mateos +8 more
semanticscholar +1 more source