Results 21 to 30 of about 307,692 (182)

Alteration of subgingival microbiome in patients with type 2 diabetes induced by diabetes treatment. [PDF]

J Diabetes Investig
ABSTRACT Aims/Introduction Diabetes and periodontal disease, a bacterial infection involving the oral microbiome, have a bidirectional relationship. However, the relationship between poor glycemic control and the oral microbiome remains unclear. The aim of this study was to assess the direct effect of intensive glycemic control on the oral microbiome ...
Inoue M, Sakanaka A, Katakami N, Nishizawa H, Omori K, Taya N, Ishikawa A, Mayumi S, Takeuchi H, Amano A, Takeshita T, Fukusaki E, Shimomura I, Kuboniwa M.   +13 more
europepmc   +2 more sources

The Urinary Phosphate to Serum Fibroblast Growth Factor 23 Ratio Is a Useful Marker of Atherosclerosis in Early-Stage Chronic Kidney Disease. [PDF]

PLoS ONE, 2016
Fibroblast growth factor 23 (FGF23) regulates mineral homeostasis. In developed renal dysfunction, FGF23 levels increase to maintain the phosphate excretion capacity. However, in diabetic patients with early-stage renal impairment, the FGF23 elevation is
Hodaka Yamada, Makoto Kuro-O, Kazuo Hara, Yuichiro Ueda, Ikuyo Kusaka, Masafumi Kakei, San-E Ishikawa   +6 more
doaj   +1 more source

Hyperglycemia-induced STING signaling activation leads to aortic endothelial injury in diabetes

Cell Communication and Signaling, 2023
Hyperglycaemia-induced endothelial dysfunction is a key factor in the pathogenesis of diabetic microangiopathy and macroangiopathy. STING, which is a newly discovered regulator of innate immunity, has also been reported to play an important role in ...
Ying An, Kang Geng, Hong-ya Wang, Sheng-rong Wan, Xiu-mei Ma, Yang Long, Yong Xu, Zong-zhe Jiang   +7 more
doaj   +1 more source

Negative Pressure Wound Therapy as a Key Strategy in the Management of Severe Diabetic Foot Ulcers in Septic Frail Patients: A Case Series. [PDF]

Int Wound J
ABSTRACT Diabetes mellitus represents a major global health challenge, with over 537 million adults currently affected worldwide. Among its complications, diabetic foot ulcers remain a leading cause of morbidity, hospitalization and amputation, imposing a significant socioeconomic burden.
Pirski MI, Malerba S, Marano L, Kur M, Skokowski J, Świerblewski M.   +5 more
europepmc   +2 more sources

The role of oxidative stress in diabetes mellitus-induced vascular endothelial dysfunction

Cardiovascular Diabetology, 2023
Diabetes mellitus is a metabolic disease characterized by long-term hyperglycaemia, which leads to microangiopathy and macroangiopathy and ultimately increases the mortality of diabetic patients.
Ying An, Bu-tuo Xu, Sheng-rong Wan, Xiu-mei Ma, Yang Long, Yong Xu, Zong-zhe Jiang   +6 more
doaj   +1 more source

Comparing the Effectiveness of Different Types of Orthoses in Preventing Diabetic Foot Ulcer Recurrence: A Systematic Review of Randomized Clinical Trials. [PDF]

J Foot Ankle Res
ABSTRACT Introduction Therapeutic orthoses, such as medical shoes and custom insoles, are used to prevent diabetic foot ulcer (DFU) recurrence. This systematic review with narrative synthesis aimed to evaluate the effectiveness of orthoses in preventing DFU recurrence compared to standard care.
Amini B, Salehi-Pourmehr H, Ghaffarzadehrad S.   +2 more
europepmc   +2 more sources

Approaches to Selection of Optimal Chemotherapy Regimens in Tuberculosis Patients with Concurrent Diabetes Mellitus

Туберкулез и болезни лёгких, 2023
The objective: to develop approaches to selection of optimal chemotherapy regimens in tuberculosis patients with concurrent diabetes mellitus (DM), by studying complications of diabetes mellitus and adverse drug reactions to anti-tuberculosis drugs ...
O. G. Komissarova, R. Yu. Abdullaev, S. V. Aleshina   +2 more
doaj   +1 more source

Laser treatment in diabetic retinopathy [PDF]

, 2007
Diabetic retinopathy is a leading cause of visual impairment and blindness in developed countries due to macular edema and proliferative diabetic retinopathy (PDR). For both complications laser treatment may offer proven therapy: the Diabetic Retinopathy
Ulbig, Michael W., Michael W. Ulbig, Neubauer, Aljoscha Steffen, Aljoscha S. Neubauer   +3 more
core   +1 more source

High fat intake leads to acute postprandial exposure to circulating endotoxin in type 2 diabetic subjects [PDF]

, 2012
OBJECTIVE-To evaluate the changes in circulating endotoxin after a high-saturated fat meal to determine whether these effects depend on metabolic disease state.
Varma, M.C., Saravanan, Ponnusamy, Saravanan, P., Tripathi, Gyanendra, Kumar, Sudhesh, Sabico, Shaun, Sabico, S., O'Hare, J.P., McTernan, P. G., Harte, A. L., Varma, Madhusudhan C., Ceriello, A., Al-Attas, Omar S., McTernan, P.G., Al-Attas, O.S., Al-Daghri, Nasser M., Ceriello, Antonio, McGee, K. C., O'Hare, J. Paul, McGee, K.M., Al-Daghri, N.M., Kumar, S., Harte, A.L., Tripathi, G.   +23 more
core   +1 more source

Screening for Osteoporosis and Diabetic Foot Among Members of Varna's Diabetic Association

Endocrinology Research and Practice, 2022
A screening study was performed with the following aim: to identify high risk patients for diabetic foot and to investigate the frequency of diabetic fool and osleoporosis among members of Varna's Diabetic Association.
Hripsime A. Bohchelian, Lidia A. Koeva
doaj   +2 more sources