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Diabetic Nephropathy

Pediatric Clinics of North America, 1984
It is estimated that about 50 per cent of all patients with Type I diabetes mellitus develop uremia during the course of their disease. Glomerular microvasculopathy is the most serious and predictable threat to longevity. Following a discussion of this disorder, the author outlines a plan for overall management of each phase of kidney disease so that ...
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Diabetic nephropathy.

Current therapy in endocrinology and metabolism, 1997
Diabetic nephropathy accounts for almost a third of all causes of ESRD. Microalbuminuria screening among diabetics can offer early detection of incipient nephropathy. Aggressive treatment with ACE inhibitors may delay the onset of overt renal failure or delay its progression.
CASTELLINO, Pietro   +2 more
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Diabetic nephropathy

Disease-a-Month, 1993
Diabetic nephropathy occurs in approximately 35% of all diabetic patients, both insulin and non-insulin dependent. It accounts for the largest proportion increase of all diseases as a cause for endstage renal disease in the United States. Certain populations, i.e., Pima Indians and Mexican and black Americans, have a higher propensity for developing ...
G L, Bakris, J H, Stein
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Nephropathy in Diabetes

2012
The most common cause of end stage renal disease (ESRD) requiring dialysis is diabetes. Both environmental and genetic factors have been postulated as the risk factors of Diabetic Nephropathy (DN). Hyperglycemia-induced metabolic and hemodynamic pathways are recognized to be mediators of kidney injury. Multiple biochemical pathways have been postulated
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Diabetic nephropathy

Irish Journal of Medical Science, 1979
Since the original recognition by Kimmelstiel and Wilson in 1936 of a characteristic nodular lesion in diabetic renal glomeruli, no simple relationship has been demonstrated between the structural and functional defects now known to exist in diabetic renal disease.
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Proteomics and Diabetic Nephropathy

Seminars in Nephrology, 2005
Diabetes mellitus is acknowledged to be a group of metabolic diseases and heterogeneous in natural history, pathogenesis, response to treatment, and disease progression and remission. Diabetic nephropathy (DN) accounts for approximately 40% of all newly diagnosed cases of end-stage renal disease.
Michael L, Merchant, Jon B, Klein
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Diabetic Nephropathy and Pregnancy

Clinical Obstetrics and Gynecology, 1991
Knowledge of the pathogenic mechanisms of diabetic nephropathy (by which hyperglycemia, hyperfiltration, and hypertension cause the gradual development of microproteinuria, mesangial expansion, and eventual glomerular closure) provides the basis for effective treatment.
C A, Combs, J L, Kitzmiller
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Diabetic nephropathy

Archives of Family Medicine, 1996
Diabetic nephropathy is an important microvascular complication of both insulin-dependent and non-insulin-dependent diabetes mellitus. It is the leading cause of end-stage renal disease. The natural course, pathogenesis, clinical evaluation, and treatment of diabetic nephropathy were reviewed, with special emphasis on recent important studies of ...
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PROGRESSION OF DIABETIC NEPHROPATHY

The Lancet, 1979
Although deterioration of renal function in diabetic nephropathy varies considerably from one diabetic to another, its rate is constant in individuals. For each patient there is a linear relation between period (months) which elapses from the time serum creatinine becomes greater than 200 mumol/l and the inverse the inverse of the serum-creatinine. The
R H, Jones   +4 more
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Smoking and Diabetic Nephropathy

Acta Medica Scandinavica, 2009
Forty-seven patients with insulin-dependent diabetes (IDDM) and diabetic nephropathy and 47 controls with IDDM without diabetic nephropathy were interviewed about their previous and current smoking habits. The patients in the two groups were matched according to sex, age, age at onset, and duration of diabetes. All patients in the nephropathy group had
G, Nordén, G, Nyberg
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