Statins and the vasculopathy of systemic sclerosis: potential therapeutic agents? [PDF]
, 2006 It has been postulated that endothelial cell injury is the initiating event in the pathogenesis of systemic sclerosis, causing attraction, attachment, migration and infiltration of activated T-cells and subsequent production of cytokines and growth ...
Derk, Chris T., Jimenez, Sergio A.
core +2 more sources
Risk factors of diabetic nephropathy with retinopathy
Linchuang shenzangbing zazhi, 2022 ObjectiveTo explore the risk factors and relationship of diabetic nephropathy （DN） with diabetic retinopathy （DR）.MethodsBetween January 2017 and January 2021，type 2 DN patients were divided into DN & retinal group （observation，n=160） and DN & ...
Liang Dong-rui +4 more
doaj
Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial. [PDF]
, 2015 Apolipoprotein L1 gene (APOL1) G1 and G2 coding variants are strongly associated with chronic kidney disease (CKD) in African Americans (AAs). Here APOL1 association was tested with baseline estimated glomerular filtration rate (eGFR), urine albumin ...
Bild, Diane E +14 more
core +1 more source
Diabetic Nephropathy without Diabetes [PDF]
Journal of Clinical Medicine, 2015 Diabetic nephropathy without diabetes (DNND), previously known as idiopathic nodular glomerulosclerosis, is an uncommon entity and thus rarely suspected; diagnosis is histological once diabetes is discarded. In this study we describe two new cases of DNND and review the literature. We analyzed all the individualized data of previous publications except
López-Revuelta, Katia +5 more
openaire +3 more sources
Aderenze alle terapie evidence-based per la prevenzione secondaria dell'infarto miocardico acuto e impatto su mortalita' e insorgenza di eventi avversi cardiovascolari [PDF]
, 2014 Background: Clinical trials have demonstrated that selected secondary prevention medications for patients after acute myocardial infarction (AMI) reduce mortality.
Lenzi, Jacopo <1985>
core +1 more source
Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]
, 2000 The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim +1 more
core +1 more source
Novel biomarkers for diabetic kidney disease [PDF]
Kidney Research and Clinical Practice, 2022 Although diabetic kidney disease (DKD) remains one of the leading causes of reduced lifespan in patients with diabetes mellitus; its prevalence has failed to decline over the past 30 years.
Chan-Young Jung, Tae-Hyun Yoo
doaj +1 more source
Managing diabetic nephropathy [PDF]
Clinical Medicine, 2010 The earliest sign of DN is the development of microalbuminuria which is associated with a significant risk of both progressive renal failure and premature death from cardiovascular disease. Optimal glycaemic and BP control, including the use of RAAS blocking drugs, can prevent, slow and even reverse the processes causing DN.
Shields, Joanne, Maxwell, Alexander P
openaire +2 more sources
The Association Between Smoking Tobacco After a Diagnosis of Diabetes and the Prevalence of Diabetic Nephropathy in the Korean Male Population [PDF]
Journal of Preventive Medicine and Public Health, 2016 Objectives: Smoking is known to be associated with nephropathy in patients with diabetes. The distinct effects of smoking before and after diabetes has been diagnosed, however, are not well characterized. We evaluated the association of cigarette smoking
Hyungseon Yeom +3 more
doaj +1 more source
Association of Vitamin D Deficiency with Diabetic Nephropathy [PDF]
Endocrinology and Metabolism, 2021 Background Low 25-hydroxyvitamin D (25OHD) levels are associated with the incidence of type 2 diabetes mellitus (T2DM). However, the association between 25OHD and metabolic health status or diabetic complications is inconclusive.
So-hyeon Hong +5 more
doaj +1 more source