The role of sirolimus in proteinuria in diabetic nephropathy rats [PDF]
Iranian Journal of Basic Medical Sciences, 2017 Objective(s): The aim of this study was to observe the impact of sirolimus on proteinuria in streptozotocin (STZ) induced diabetic rats. Materials and Methods: Rats were given a single injection of STZ to induce diabetic rat model.
JinJun Wang +5 more
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Histopathology of Diabetic Nephropathy [PDF]
Seminars in Nephrology, 2007 The clinical manifestations of diabetic nephropathy, proteinuria, increased blood pressure, and decreased glomerular filtration rate, are similar in type 1 and type 2 diabetes; however, the renal lesions underlying renal dysfunction in the 2 conditions may differ.
FIORETTO, PAOLA, MAUER M.
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Protein kinase R-like endoplasmic reticulum kinase pathway and diabetic kidney disease
Linchuang shenzangbing zazhi, 2020 Endoplasmic reticulum stress is closely related to the occurrence and development of diabetic kidney disease.As an important signaling pathway induced by endoplasmic reticulum stress,protein kinase R-like endoplasmic reticulum kinase(PERK)pathway can ...
庞欣欣 +5 more
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The rs3844492/ARHGAP22 and rs741301/ELMO1 polymorphisms are associated with changes in laboratory markers of renal damage among patients with type 2 diabetes mellitus [PDF]
Archives of Endocrinology and MetabolismObjective: To investigate the association between the rs3844492/ARHGAP22 and rs741301/ELMO1 polymorphisms and diabetic kidney disease in patients with type 2 diabetes mellitus.
Luciane Moretto +8 more
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Journal of Diabetes InvestigationBackground and Aims To prevent end‐stage renal disease caused by diabetic kidney disease, we created a predictive model for high‐risk patients using machine learning.
Mari Watanabe +6 more
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Novel thinking of renal pathology on the diagnosis and prognosis of diabetic nephropathy
Linchuang shenzangbing zazhi, 2021 Diabetes mellitus（DM）has been a great challenge to human health. is As one of the most important complications, diabetic nephropathy（DN）is a major cause of end-stage renal disease（ESRD）.
Zhou Ting, Wang Nian-song, Fan Ying
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Idiopathic nodular glomerulosclerosis and differential diagnosis
Brazilian Journal of Nephrology, 2020 Introduction: Idiopathic nodular glomerulosclerosis (ING) is a condition that has a vasculopathic glomerular histological pattern. Case presentation: The authors present the case of a 44-year-old Hispanic smoker female with hypertension and peripheral ...
Sergio Raúl Alvizures Solares +4 more
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Managing diabetic nephropathy [PDF]
Clinical Medicine, 2010 The earliest sign of DN is the development of microalbuminuria which is associated with a significant risk of both progressive renal failure and premature death from cardiovascular disease. Optimal glycaemic and BP control, including the use of RAAS blocking drugs, can prevent, slow and even reverse the processes causing DN.
Shields, Joanne, Maxwell, Alexander P
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Amorphophallus campanulatus tuber extract protects diabetic nephropathy in streptozotocin-induced diabetic nephropathy rat model by regulating oxidative stress and TNF-α inflammatory pathway [PDF]
Acta Cirúrgica BrasileiraPurpose: To assess the effect of Amorphophallus campanulatus tuber (Ac) extract in the protection of diabetic nephropathy in streptozotocin (STZ) induced diabetic nephropathy (DN) rat model.
Li Fan +2 more
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Neutrophil-Linked Inflammatory Mechanisms and Biomarkers in Diabetic Microvascular Complications [PDF]
Diabetes & Metabolism JournalDiabetic microvascular complications, including nephropathy, retinopathy, and neuropathy, are major causes of morbidity in diabetes. Increasing evidence highlights neutrophils as key contributors to the chronic inflammatory processes underlying these ...
Junseo Kim +10 more
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