Results 211 to 220 of about 111,907 (307)

Cholesterol accumulation in monocytes is associated with the severity of diabetic complications and the efficacy of glycemic control interventions in patients with type 2 diabetes

open access: yesJournal of Diabetes Investigation, EarlyView.
This study reveals that monocyte cholesterol accumulation correlates with the severity of diabetic complications and predicts post‐discharge glycemic deterioration. These findings suggest that monocytic cholesterol serves as a novel translational biomarker reflecting ‘metabolic memory’ and therapeutic resistance in patients with type 2 diabetes ...
Hideyuki Okuma   +3 more
wiley   +1 more source

Causal effects of lifestyle and socioeconomic factors on diabetes and its complications and comorbidities: A Mendelian randomization study

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims Diabetes poses a growing global health burden. This study investigated the causal effects of lifestyle and socioeconomic factors on diabetes risk and related complications and comorbidities. Materials and Methods We applied two‐sample univariable and multivariable Mendelian randomization to assess the causal impact of 26 lifestyle and ...
Qian Yu   +5 more
wiley   +1 more source

DPP4/CD32b/NF-κB Circuit: A Novel Druggable Target for Inhibiting CRP-Driven Diabetic Nephropathy. [PDF]

open access: yesMol Ther
Ming-Kuen Tang P   +6 more
europepmc   +1 more source

Improved prognosis prediction of all‐cause mortality and cardiovascular events by combined assessment of both ankle‐brachial index and brachial‐ankle pulse wave velocity in individuals with diabetes: The Kyushu prevention study for atherosclerosis, a prospective, multicenter survey

open access: yesJournal of Diabetes Investigation, EarlyView.
A novel algorithm combining ABI and baPWV was developed to predict mortality and CVD risk in individuals with diabetes. This algorithm improved the accuracy of mortality and CVD risk assessment and was independent from the Framingham Risk Score. ABSTRACT Aims/Introduction People with diabetes exhibit early‐stage cardiovascular disease (CVD).
Erina Eto   +6 more
wiley   +1 more source

Type 1 diabetes‐specific distress among adults with type 1 diabetes in Japan

open access: yesJournal of Diabetes Investigation, EarlyView.
This study investigated the prevalence and characteristics of diabetes distress (DD) in 117 Japanese adults with type 1 diabetes using the Type 1 Diabetes Distress Scale (T1‐DDS), PAID, and HFS. Moderate and high DD were observed in 30.8% and 16.2% of participants, respectively.
Naoki Sakane   +3 more
wiley   +1 more source

Effect of sodium–glucose cotransporter 2 inhibitors on heart failure readmission in older patients with diabetes: A Japanese claims‐based cohort study

open access: yesJournal of Diabetes Investigation, EarlyView.
SGLT2 inhibitor use at discharge was associated with a reduced risk of heart failure readmission in elderly patients with diabetes, with no significant differences among individual agents. ABSTRACT Aims To evaluate the effect of sodium–glucose cotransporter 2 inhibitor (SGLT2i) administration at hospital discharge on heart failure (HF) readmission ...
Kazuya Hiura   +3 more
wiley   +1 more source

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