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Disease-a-Month, 1993
Diabetic nephropathy occurs in approximately 35% of all diabetic patients, both insulin and non-insulin dependent. It accounts for the largest proportion increase of all diseases as a cause for endstage renal disease in the United States. Certain populations, i.e., Pima Indians and Mexican and black Americans, have a higher propensity for developing ...
G L, Bakris, J H, Stein
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Diabetic nephropathy occurs in approximately 35% of all diabetic patients, both insulin and non-insulin dependent. It accounts for the largest proportion increase of all diseases as a cause for endstage renal disease in the United States. Certain populations, i.e., Pima Indians and Mexican and black Americans, have a higher propensity for developing ...
G L, Bakris, J H, Stein
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2012
The most common cause of end stage renal disease (ESRD) requiring dialysis is diabetes. Both environmental and genetic factors have been postulated as the risk factors of Diabetic Nephropathy (DN). Hyperglycemia-induced metabolic and hemodynamic pathways are recognized to be mediators of kidney injury. Multiple biochemical pathways have been postulated
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The most common cause of end stage renal disease (ESRD) requiring dialysis is diabetes. Both environmental and genetic factors have been postulated as the risk factors of Diabetic Nephropathy (DN). Hyperglycemia-induced metabolic and hemodynamic pathways are recognized to be mediators of kidney injury. Multiple biochemical pathways have been postulated
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Irish Journal of Medical Science, 1979
Since the original recognition by Kimmelstiel and Wilson in 1936 of a characteristic nodular lesion in diabetic renal glomeruli, no simple relationship has been demonstrated between the structural and functional defects now known to exist in diabetic renal disease.
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Since the original recognition by Kimmelstiel and Wilson in 1936 of a characteristic nodular lesion in diabetic renal glomeruli, no simple relationship has been demonstrated between the structural and functional defects now known to exist in diabetic renal disease.
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Proteomics and Diabetic Nephropathy
Seminars in Nephrology, 2005Diabetes mellitus is acknowledged to be a group of metabolic diseases and heterogeneous in natural history, pathogenesis, response to treatment, and disease progression and remission. Diabetic nephropathy (DN) accounts for approximately 40% of all newly diagnosed cases of end-stage renal disease.
Michael L, Merchant, Jon B, Klein
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Diabetic Nephropathy and Pregnancy
Clinical Obstetrics and Gynecology, 1991Knowledge of the pathogenic mechanisms of diabetic nephropathy (by which hyperglycemia, hyperfiltration, and hypertension cause the gradual development of microproteinuria, mesangial expansion, and eventual glomerular closure) provides the basis for effective treatment.
C A, Combs, J L, Kitzmiller
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Archives of Family Medicine, 1996
Diabetic nephropathy is an important microvascular complication of both insulin-dependent and non-insulin-dependent diabetes mellitus. It is the leading cause of end-stage renal disease. The natural course, pathogenesis, clinical evaluation, and treatment of diabetic nephropathy were reviewed, with special emphasis on recent important studies of ...
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Diabetic nephropathy is an important microvascular complication of both insulin-dependent and non-insulin-dependent diabetes mellitus. It is the leading cause of end-stage renal disease. The natural course, pathogenesis, clinical evaluation, and treatment of diabetic nephropathy were reviewed, with special emphasis on recent important studies of ...
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PROGRESSION OF DIABETIC NEPHROPATHY
The Lancet, 1979Although deterioration of renal function in diabetic nephropathy varies considerably from one diabetic to another, its rate is constant in individuals. For each patient there is a linear relation between period (months) which elapses from the time serum creatinine becomes greater than 200 mumol/l and the inverse the inverse of the serum-creatinine. The
R H, Jones +4 more
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Smoking and Diabetic Nephropathy
Acta Medica Scandinavica, 2009Forty-seven patients with insulin-dependent diabetes (IDDM) and diabetic nephropathy and 47 controls with IDDM without diabetic nephropathy were interviewed about their previous and current smoking habits. The patients in the two groups were matched according to sex, age, age at onset, and duration of diabetes. All patients in the nephropathy group had
G, Nordén, G, Nyberg
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The pathogenesis of diabetic nephropathy
Nature Clinical Practice Endocrinology & Metabolism, 2008Between 20% and 40% of patients with diabetes ultimately develop diabetic nephropathy, which in the US is the most common cause of end-stage renal disease requiring dialysis. Diabetic nephropathy has several distinct phases of development and multiple mechanisms contribute to the development of the disease and its outcomes.
Suma, Dronavalli +2 more
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Diabetes and nephropathy is not always equal to diabetic nephropathy
The British Journal of Diabetes & Vascular Disease, 2013In a busy diabetes clinic, it is always easy for the diabetologist to equate nephropathy and diabetes to “diabetic nephropathy”. Certain clinical clues should arouse suspicion of non-diabetic renal disease as this may have important implications in patient management.
Krishnan Swaminathan +3 more
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