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Clinical spectrum and diagnosis of diabetic neuropathies [PDF]
Neuropathy is the most prevalent microvascular complication of diabetes mellitus; it encompasses distal symmetric polyneuropathy, autonomic neuropathy, radiculoplexus neuropathy, mononeuropathy, and treatment-induced neuropathy.
Jeeyoung Oh
doaj +2 more sources
There are currently no treatments available (beyond optimal control of hyperglycemia) that arrest or reverse progressive diabetic polyneuropathy. Consultation with a diabetologist is indicated for patients with poorly controlled disease and polyneuropathy. Immunotherapy for diabetic lumbosacral plexopathy has been advocated but is not supported to date
Anandhanarayanan A +4 more
europepmc +5 more sources
Identifying common genetic risk factors of diabetic neuropathies [PDF]
Type 2 diabetes mellitus (T2DM) is a global public health problem of epidemic proportions, with 60-70% of affected individuals suffering from associated neurovascular complications that act on multiple organ systems.
Ini-Isabee eWitzel +6 more
doaj +2 more sources
This article provides an up-to-date review of the diagnosis and management of the most common neuropathies that occur in patients with diabetes.The prevalence of diabetes continues to grow worldwide and, as a result, the burden of diabetic neuropathies is also increasing. Most diabetic neuropathies are caused by hyperglycemic effects on small and large
Elafros MA, Callaghan BC.
europepmc +3 more sources
This article provides an overview for understanding the diagnosis, pathogenesis, and management of diabetic neuropathy.New information about the pathogenesis of diabetic neuropathy continues to emerge, which will lead to identifying new drug targets. It is clear that the natural history of diabetic neuropathy is changing and the rate of progression is ...
Russell JW, Zilliox LA.
europepmc +4 more sources
Evaluation of sensory loss in the feet and associated factors in ambulatory patients with diabetes: a cross-sectional study [PDF]
Objective: To determine the prevalence of protective sensory loss in patients with diabetes mellitus at a university hospital and to identify clinical and sociodemographic factors associated with this condition.
Rafael Gusmão Santos Barreto +4 more
doaj +2 more sources
Inflammation as a Therapeutic Target for Diabetic Neuropathies [PDF]
Rodica Pop-Busui +2 more
exaly +2 more sources
AbstractDiabetes mellitus is becoming increasingly common worldwide. As this occurs, there will be an increase in the prevalence of known comorbidities from this disorder of glucose metabolism. One of the most disabling adverse comorbidities is diabetic neuropathy.
Elina, Zakin +2 more
+8 more sources
Differential diagnosis of polyneuropathies in diabetes mellitus
Diabetic polyneuropathy (DPN) is heterogeneous in its clinical course and clinical manifestations. Depending on the primary lesion of large or small nerve fibers, different onset, course and clinical manifestations of polyneuropathy are possible.
V. N. Khramilin
doaj +1 more source
In this review, an in-depth anatomic and molecular pathogenesis of diabetic neuropathy is provided. Classifications and clinical manifestations of diabetic neuropathy are discussed. The current modalities of treatment and clinical research on this disorder are summarized.
Christopher, Bibbo, Dipak V, Patel
openaire +4 more sources

