Results 1 to 10 of about 80,322 (158)
Nature Reviews Disease Primers, 2019 AbstractDiabetes mellitus is becoming increasingly common worldwide. As this occurs, there will be an increase in the prevalence of known comorbidities from this disorder of glucose metabolism. One of the most disabling adverse comorbidities is diabetic neuropathy.
Eva L Feldman +2 more
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Journal of Diabetes Investigation, 2021 Aims/Introduction To examine the prevalence of falls and fractures, and the association with symptoms of diabetic polyneuropathy (DPN) in patients with recently diagnosed type 2 diabetes.
Karolina Snopek Khan +7 more
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A Drosophila model of diabetic neuropathy reveals a role of proteasome activity in the glia
iScience, 2023 Summary: Diabetic peripheral neuropathy (DPN) is the most common chronic, progressive complication of diabetes mellitus. The main symptom is sensory loss; the molecular mechanisms are not fully understood.
Mari Suzuki +7 more
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Data in Brief, 2021 The accumulation of pathogenic misfolded proteins is believed to be a common mechanism of generation of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and polyglutamine (polyQ) diseases.
Masaki Oba +3 more
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Role of pyruvate in maintaining cell viability and energy production under high-glucose conditions
Scientific Reports, 2021 Pyruvate functions as a key molecule in energy production and as an antioxidant. The efficacy of pyruvate supplementation in diabetic retinopathy and nephropathy has been shown in animal models; however, its significance in the functional maintenance of ...
Hideji Yako +7 more
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Seminars in Neurology, 2015 Diabetes mellitus is a common condition and diabetics are prone to develop a spectrum of neuropathic complications ranging from symmetric and diffuse to asymmetric and focal neuropathies that may be associated with significant morbidity. Diabetic sensorimotor polyneuropathy is the most common of these complications, occurring in patients with type 1 ...
Aaron, Izenberg +2 more
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Experimental and Clinical Endocrinology & Diabetes, 2014 Neuropathies related to diabetes mellitus can affect 60-70% of patients with diabetes. These can include peripheral polyneuropathies, mononeuropathies, and autonomic neuropathies. Control of glucose, lipids, and hypertension and cessation of smoking can limit onset and progression of these neuropathies. Besides control of the above listed risk factors,
Ziegler D, Keller J, Maier C, Pannek J
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Diabetic corneal neuropathy as a surrogate marker for diabetic peripheral neuropathy
Neural Regeneration Research, 2022 Diabetic neuropathy is a prevalent microvascular complication of diabetes mellitus, affecting nerves in all parts of the body including corneal nerves and peripheral nervous system, leading to diabetic corneal neuropathy and diabetic peripheral ...
Wei Zheng So +6 more
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Clinical spectrum and diagnosis of diabetic neuropathies [PDF]
The Korean Journal of Internal Medicine, 2020 Neuropathy is the most prevalent microvascular complication of diabetes mellitus; it encompasses distal symmetric polyneuropathy, autonomic neuropathy, radiculoplexus neuropathy, mononeuropathy, and treatment-induced neuropathy.
Jeeyoung Oh
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Foot and Ankle Clinics, 2006 In this review, an in-depth anatomic and molecular pathogenesis of diabetic neuropathy is provided. Classifications and clinical manifestations of diabetic neuropathy are discussed. The current modalities of treatment and clinical research on this disorder are summarized.
Christopher, Bibbo, Dipak V, Patel
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