Results 1 to 10 of about 314,563 (316)
Canadian Journal of Diabetes, 2018 The genetic neuropathies are a clinically and genetically heterogeneous group of diseases that can broadly be classified into two groups: those in which the neuropathy is the sole or primary part of the disorder (Charcot-Marie-Tooth disease, CMT) and those in which the neuropathy is part of a more generalized neurologic or multisystem disorder (e.g ...
Chiara, Pisciotta, Michael E, Shy
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Biomedicines, 2022 Paclitaxel is a widely used anticancer drug that induces dose-limiting peripheral neuropathy. Mitochondrial dysfunction has been implicated in paclitaxel-induced neuronal damage and in the onset of peripheral neuropathy. We have previously shown that the
Hye-Ji Jang +4 more
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Journal of Diabetes Investigation, 2021 Aims/Introduction To examine the prevalence of falls and fractures, and the association with symptoms of diabetic polyneuropathy (DPN) in patients with recently diagnosed type 2 diabetes.
Karolina Snopek Khan +7 more
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Pharmaceuticals, 2021 Preclinical evidence, accumulated over the past decade, indicates that the angiotensin II type 2 receptor (AT2R) stimulation exerts significant neuroprotective effects in various animal models of neuronal injury, notably in the central nervous system ...
Aurore Danigo +9 more
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Ramipril Alleviates Oxaliplatin-Induced Acute Pain Syndrome in Mice
Frontiers in Pharmacology, 2021 Oxaliplatin is a key drug for colorectal cancer that causes OXP-induced peripheral neuropathy, a dose-limiting effect characterized by cold and tactile hyperesthesia.
Hichem Bouchenaki +10 more
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Antioxidants, 2022 Hesperidin is derived from citrus fruits among other plants. Hesperidin was methylated to increase its solubility, generating hesperidin methyl chalcone (HMC), an emerging flavonoid that possess anti-inflammatory and antioxidant properties.
Allan J. C. Bussmann +12 more
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Resolvin D5 (RvD5) Reduces Renal Damage Caused by LPS Endotoxemia in Female Mice
Molecules, 2022 In self-revolving gram-negative Escherichia coli infection, Resolvin D5 (RvD5) was found to enhance bacteria phagocytosis and reduce the production of inflammatory mediators, contributing to the resolution of infection. LPS (lipopolysaccharide) is a gram-
Renato D. R. Cardoso +12 more
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Molecules, 2023 Arthroplasty is an orthopedic surgical procedure that replaces a dysfunctional joint by an orthopedic prosthesis, thereby restoring joint function. Upon the use of the joint prosthesis, a wearing process begins, which releases components such as titanium
Nayara A. Artero +15 more
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Role of pyruvate in maintaining cell viability and energy production under high-glucose conditions
Scientific Reports, 2021 Pyruvate functions as a key molecule in energy production and as an antioxidant. The efficacy of pyruvate supplementation in diabetic retinopathy and nephropathy has been shown in animal models; however, its significance in the functional maintenance of ...
Hideji Yako +7 more
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Cells, 2023 Chikungunya virus is an arthropod-borne infectious agent that causes Chikungunya fever disease. About 90% of the infected patients experience intense polyarthralgia, affecting mainly the extremities but also the large joints such as the knees.
Carina Z. Segato-Vendrameto +18 more
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