Results 41 to 50 of about 342,736 (199)
Electrical impedance myography detects dystrophin-related muscle changes in mdx mice
Skeletal Muscle, 2023 Background The lack of functional dystrophin protein in Duchenne muscular dystrophy (DMD) causes chronic skeletal muscle inflammation and degeneration. Therefore, the restoration of functional dystrophin levels is a fundamental approach for DMD therapy ...
Tetsuaki Hiyoshi +10 more
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MicroRNA 200c-3p regulates autophagy via upregulation of endoplasmic reticulum stress in PC-3 cells
Cancer Cell International, 2018 Background Autophagy is a response to cellular and environmental conditions and facilitates cell survival. Here, we investigated the role of ectopic expression of microRNA (miRNA) 200c-3p in autophagy. Methods miRNA mimics were used to overexpress miRNAs.
Eun Jung Sohn
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Journal of the Peripheral Nervous System, 2001 The occurrence of a peripheral neuropathy (PN) in association with a monoclonal gammopathy is quite common and suggests that monoclonal proteins may play a pathogenetic role in peripheral nervous system damage. In fact, paraproteinemic PN constitute an heterogeneous group of disorders related to various pathogenetic factors, and the histopathologic ...
openaire +3 more sources
Transcriptional Fingerprint of Hypomyelination in and () Mice
ASN Neuro, 2016 The transcriptional program that controls oligodendrocyte maturation and central nervous system (CNS) myelination has not been fully characterized. In this study, we use high-throughput RNA sequencing to analyze how the loss of a key transcription factor,
Joshua D. Aaker +6 more
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Data in Brief, 2021 The accumulation of pathogenic misfolded proteins is believed to be a common mechanism of generation of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and polyglutamine (polyQ) diseases.
Masaki Oba +3 more
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Diabetes Care, 2007 Perspectives on the News commentaries are now part of a new, free monthly CME activity. The Mount Sinai School of Medicine, New York, New York, is designating this activity for 2.0 AMA PRA Category 1 credits. If you wish to participate, review this article and visit www.diabetes.procampus.net to complete a posttest and receive a certificate.
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Deutsches Ärzteblatt international, 2018 Hereditary peripheral neuropathies constitute a large group of genetic diseases, with an overall prevalence of 1:2500. In recent years, the use of so-called next-generation sequencing (NGS) has led to the identification of many previously unknown involved genes and genetic defects that cause neuropathy.
Katja, Eggermann +5 more
openaire +2 more sources
Frontiers in Pharmacology, 2018 Background: Gout is the most common inflammatory arthritis worldwide. It is a painful inflammatory disease induced by the deposition of monosodium urate (MSU) crystals in the joints and peri-articular tissues.
Victor Fattori +11 more
doaj +1 more source
Auditory neuropathy in a patient exposed to xylene: case report [PDF]
, 2009 Objective: To report the case of an adult patient who developed auditory complaints following xylene exposure, and to review the literature on the effects of solvent exposure on hearing.Case report: The patient presented with a gradual deterioration in ...
Draper, THJ, Bamiou, DE
core
The neuroinflammatory role of Schwann cells in disease
Neurobiology of Disease, 2013 Peripheral neuropathies are associated with a variety of clinical symptoms ranging from motor and sensory symptoms to autonomic dysfunction. The primary disease causes for peripheral nerve disorders are also very heterogeneous, including genetic causes ...
Elke Ydens +5 more
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