Results 41 to 50 of about 1,254,591 (276)

Green synthesis of silver nanoparticles by Nigella sativa extract alleviates diabetic neuropathy through anti-inflammatory and antioxidant effects

open access: yesSaudi Journal of Biological Sciences, 2020
Green synthesis of silver nanoparticles has gained great interest among scientists. In view of this data, we conducted this study to identify the ameliorative effect of green synthesis of silver nanoparticles using Nigella sativa extract in diabetic ...
Maha I. Alkhalaf   +2 more
semanticscholar   +1 more source

Glycated Hemoglobin (HbA1c) as a Biomarker for Diabetic Foot Peripheral Neuropathy

open access: yesDiseases, 2021
Background: Diabetic peripheral neuropathy (DPN) is known to predict foot ulceration, lower-extremity amputation and mortality. Patients with diabetes mellitus have a predisposition toward developing chronic inflammatory demyelinating polyneuropathy, and
Giulia Casadei   +2 more
semanticscholar   +1 more source

Diabetic neuropathy: cutting-edge research and future directions

open access: yesSignal Transduction and Targeted Therapy
Diabetic neuropathy (DN) is a prevalent and debilitating complication of diabetes mellitus, significantly impacting patient quality of life and contributing to morbidity and mortality.
Yang Yang   +6 more
semanticscholar   +1 more source

Immortalized Schwann cell lines as useful tools for pathogenesis-based therapeutic approaches to diabetic peripheral neuropathy

open access: yesFrontiers in Endocrinology
Growing evidence suggests that hyperglycemia-related abnormalities in Schwann cells play a pivotal role in the development and progression of diabetic peripheral neuropathy (DPN).
Kazunori Sango   +4 more
doaj   +1 more source

Diabetic peripheral neuropathy: pathogenetic mechanisms and treatment

open access: yesFrontiers in Endocrinology
Diabetic peripheral neuropathy (DPN) refers to the development of peripheral nerve dysfunction in patients with diabetes when other causes are excluded. Diabetic distal symmetric polyneuropathy (DSPN) is the most representative form of DPN. As one of the
Jinxi Zhu   +8 more
semanticscholar   +1 more source

The circ_0002538/miR-138-5p/plasmolipin axis regulates Schwann cell migration and myelination in diabetic peripheral neuropathy

open access: yesNeural Regeneration Research, 2023
Circular RNAs (circRNAs) play a vital role in diabetic peripheral neuropathy. However, their expression and function in Schwann cells in individuals with diabetic peripheral neuropathy remain poorly understood.
Yu-Tian Liu   +12 more
doaj   +1 more source

Spectrum of Diabetic Neuropathy: New Insights in Diagnosis and Treatment.

open access: yesAnnual Review of Medicine
Diabetic neuropathy is a highly prevalent complication of diabetes. It consists of a broad range of neuropathic conditions, such as distal symmetric polyneuropathy and various forms of autonomic neuropathies involving the cardiovascular, gastrointestinal,
Brendan R. Dillon   +2 more
semanticscholar   +1 more source

Diabetic neuropathy and neuropathic pain: a (con)fusion of pathogenic mechanisms?

open access: yesPain, 2020
Neuropathy is a common complication of long-term diabetes that impairs quality of life by producing pain, sensory loss and limb amputation. The presence of neuropathy in both insulin-deficient (type 1) and insulin resistant (type 2) diabetes along with ...
N. Calcutt
semanticscholar   +1 more source

The Effects of Co-Culturing ND7/23 Sensory Neuron-like Cells and IFRS1 Schwann Cells on Myelination: A Single-Arm Nonrandomized Study

open access: yesNeurology International
Background/Objectives: Co-culture models of neurons and Schwann cells have been used to explore the mechanisms of myelination during development, axonal regeneration after injury, and the pathogenesis of various demyelinating neuropathies.
Shizuka Takaku, Kazunori Sango
doaj   +1 more source

Screening techniques to identify occurrence of peripheral neuropathy among diabetic patients [PDF]

open access: yesPort Said Scientific Journal of Nursing, 2015
Background  Neuropathy is the greatest source of morbidity associated with diabetes, affecting up to 50% of those with long-standing disease, and pain as a symptom of neuropathy may be seen in as many as one third of all patients with diabetes.
Elsaida Bagdady
doaj   +1 more source

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