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Medical Clinics of North America, 1998
Better clinical characteristics and a standardized approach to the definition of neuropathy has enabled us to define more precisely the natural history of diabetic neuropathy. Detailed studies on the pathology and pathogenesis have allowed dissection of important pathogenetic pathways.
A J, Boulton, R A, Malik
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Better clinical characteristics and a standardized approach to the definition of neuropathy has enabled us to define more precisely the natural history of diabetic neuropathy. Detailed studies on the pathology and pathogenesis have allowed dissection of important pathogenetic pathways.
A J, Boulton, R A, Malik
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Current Opinion in Neurology, 1994
It has been generally accepted that diabetic neuropathy is associated with substantial morbidity and increased mortality, and that aldose reductase inhibitors are of potential therapeutic value, whereas the beneficial effect of strict insulin treatment is questionable.
Jakobsen, J, Sidenius, P
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It has been generally accepted that diabetic neuropathy is associated with substantial morbidity and increased mortality, and that aldose reductase inhibitors are of potential therapeutic value, whereas the beneficial effect of strict insulin treatment is questionable.
Jakobsen, J, Sidenius, P
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Clinical manifestations and current treatment options for diabetic neuropathies.
Endocrine Practice, 2007OBJECTIVE To review the clinical manifestations and current treatment options for diabetic neuropathies, one of the most common complications of diabetes mellitus.
Carolina M Casellini, A. Vinik
semanticscholar +1 more source
Annual Review of Medicine, 1990
Diabetic neuropathy, the most common peripheral neuropathy in the Western world, is responsible for most limb amputations and considerable morbidity in diabetic patients. Although it is a sequela to insulin deficiency and/or hyperglycemia, its exact pathogenetic mechanism remains unclear.
D A, Greene +3 more
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Diabetic neuropathy, the most common peripheral neuropathy in the Western world, is responsible for most limb amputations and considerable morbidity in diabetic patients. Although it is a sequela to insulin deficiency and/or hyperglycemia, its exact pathogenetic mechanism remains unclear.
D A, Greene +3 more
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Annals of Neurology, 1984
AbstractPeripheral nerve disorders are important late complications of diabetes mellitus. Polyneuropathy, which may involve varying proportions of sensory, motor, and autonomic fibers, is considered the consequence of metabolic derangements that result from chronic hyperglycemia.
M J, Brown, A K, Asbury
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AbstractPeripheral nerve disorders are important late complications of diabetes mellitus. Polyneuropathy, which may involve varying proportions of sensory, motor, and autonomic fibers, is considered the consequence of metabolic derangements that result from chronic hyperglycemia.
M J, Brown, A K, Asbury
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Clinical aspects of diabetic neuropathies.
Diabetes Metabolism Reviews, 1988Diabetic neuropathy is a common complication of diabetes that may be associated both with considerable morbidity (painful polyneuropathy, neuropathic ulceration) and mortality (autonomic neuropathy).
A. Vinik, B. Mitchell
semanticscholar +1 more source
Endocrinology and Metabolism Clinics of North America, 2013
Diabetic neuropathy (DN) is the most common and troublesome complication of diabetes mellitus, leading to the greatest morbidity and mortality and resulting in a huge economic burden for diabetes care. The clinical assessment of diabetic peripheral neuropathy and its treatment options are multifactorial.
Aaron I, Vinik +3 more
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Diabetic neuropathy (DN) is the most common and troublesome complication of diabetes mellitus, leading to the greatest morbidity and mortality and resulting in a huge economic burden for diabetes care. The clinical assessment of diabetic peripheral neuropathy and its treatment options are multifactorial.
Aaron I, Vinik +3 more
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Physical Medicine and Rehabilitation Clinics of North America, 2001
Diabetes mellitus is a systemic disorder with a significant impact on the peripheral nervous system. Over half of the 15 million patients with diabetes mellitus in the United States have some form of diabetic neuropathy. Individuals with diabetes may develop acute or subacute painful polyneuropathy, proximal motor neuropathy, autonomic neuropathy ...
T H, Wein, J W, Albers
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Diabetes mellitus is a systemic disorder with a significant impact on the peripheral nervous system. Over half of the 15 million patients with diabetes mellitus in the United States have some form of diabetic neuropathy. Individuals with diabetes may develop acute or subacute painful polyneuropathy, proximal motor neuropathy, autonomic neuropathy ...
T H, Wein, J W, Albers
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