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DIABETIC NEUROPATHY

Medical Clinics of North America, 1998
Better clinical characteristics and a standardized approach to the definition of neuropathy has enabled us to define more precisely the natural history of diabetic neuropathy. Detailed studies on the pathology and pathogenesis have allowed dissection of important pathogenetic pathways.
A J, Boulton, R A, Malik
openaire   +5 more sources

Diabetic Neuropathy

Experimental and Clinical Endocrinology & Diabetes, 2014
Neuropathies related to diabetes mellitus can affect 60-70% of patients with diabetes. These can include peripheral polyneuropathies, mononeuropathies, and autonomic neuropathies. Control of glucose, lipids, and hypertension and cessation of smoking can limit onset and progression of these neuropathies. Besides control of the above listed risk factors,
Dan, Ziegler   +3 more
openaire   +7 more sources

Diabetic Neuropathies

Diabetes Care, 1992
Diabetic neuropathy is a common complication of diabetes that may be associated both with considerable morbidity (painful polyneuropathy, neuropathic ulceration) and mortality (autonomic neuropathy). The epidemiology and natural history of diabetic neuropathy is clouded with uncertainty, largely caused by confusion in the definition and measurement of ...
A I, Vinik   +5 more
openaire   +2 more sources

Diabetic Neuropathy

Annual Review of Medicine, 1990
Diabetic neuropathy, the most common peripheral neuropathy in the Western world, is responsible for most limb amputations and considerable morbidity in diabetic patients. Although it is a sequela to insulin deficiency and/or hyperglycemia, its exact pathogenetic mechanism remains unclear.
D A, Greene   +3 more
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Diabetic neuropathies

Muscle & Nerve, 2020
AbstractDiabetic neuropathies are the most common type of neuropathies seen in clinical practice. These neuropathies can range clinically from asymptomatic to manifesting symptoms caused by motor, sensory, and autonomic nerve dysfunction. These neuropathies can affect the peripheral nervous system, pain receptors, cardiovascular, urogenital, and ...
Kamakshi, Patel   +2 more
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Diabetic neuropathy

Annals of Neurology, 1984
AbstractPeripheral nerve disorders are important late complications of diabetes mellitus. Polyneuropathy, which may involve varying proportions of sensory, motor, and autonomic fibers, is considered the consequence of metabolic derangements that result from chronic hyperglycemia.
M J, Brown, A K, Asbury
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Diabetic neuropathy

Clinics in Endocrinology and Metabolism, 1972
Many factors contribute to the nerve damage of diabetes--metabolic (myo-inositol), microvascular, glycosylation and ageing. The variety of clinical syndromes indicates the complexity of the disease. Measurement of peripheral and autonomic nerve function is improving allowing the establishment of prospective natural history and therapeutic studies ...
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Diabetic neuropathy

Current Opinion in Neurology, 1994
It has been generally accepted that diabetic neuropathy is associated with substantial morbidity and increased mortality, and that aldose reductase inhibitors are of potential therapeutic value, whereas the beneficial effect of strict insulin treatment is questionable.
Jakobsen, J, Sidenius, P
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Diabetic Neuropathy

Endocrinology and Metabolism Clinics of North America, 2013
Diabetic neuropathy (DN) is the most common and troublesome complication of diabetes mellitus, leading to the greatest morbidity and mortality and resulting in a huge economic burden for diabetes care. The clinical assessment of diabetic peripheral neuropathy and its treatment options are multifactorial.
Aaron I, Vinik   +3 more
openaire   +4 more sources

Diabetic Neuropathies

Physical Medicine and Rehabilitation Clinics of North America, 2001
Diabetes mellitus is a systemic disorder with a significant impact on the peripheral nervous system. Over half of the 15 million patients with diabetes mellitus in the United States have some form of diabetic neuropathy. Individuals with diabetes may develop acute or subacute painful polyneuropathy, proximal motor neuropathy, autonomic neuropathy ...
T H, Wein, J W, Albers
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