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Diabetic Neuropathies [PDF]

Seminars in Neurology, 2015
Diabetes mellitus is a common condition and diabetics are prone to develop a spectrum of neuropathic complications ranging from symmetric and diffuse to asymmetric and focal neuropathies that may be associated with significant morbidity. Diabetic sensorimotor polyneuropathy is the most common of these complications, occurring in patients with type 1 ...
Aaron, Izenberg, Bruce A, Perkins, Vera, Bril   +2 more
openaire   +2 more sources

Association of serum calprotectin with peripheral neuropathy in patients with type 2 diabetes mellitus

Journal of Family Medicine and Primary Care, 2021
Introduction: Peripheral neuropathy is a common microvascular complication in patients with type 2 diabetes mellitus with a prevalence of around 50%. Objectives: This prospective observational cross-sectional study was done to assess serum calprotectin ...
Ramanathan Velayutham, Pradeep Pankajakshan Nair, Prashant S Adole, Vadivelan Mehalingam   +3 more
doaj   +1 more source

Artificial Intelligence for Diabetes Case Management: The Intersection of Physical and Mental Health [PDF]

Informatics in Medicine Unlocked, 2019, 2018
Diabetes is a major public health problem in the United States, affecting roughly 30 million people. Diabetes complications, along with the mental health comorbidities that often co-occur with them, are major drivers of high healthcare costs, poor outcomes, and reduced treatment adherence in diabetes.
arxiv   +1 more source

An artificial intelligence-based deep learning algorithm for the diagnosis of diabetic neuropathy using corneal confocal microscopy: a development and validation study

Diabetologia, 2019
Aims/hypothesis Corneal confocal microscopy is a rapid non-invasive ophthalmic imaging technique that identifies peripheral and central neurodegenerative disease.
Bryan M. Williams, D. Borroni, Rongjun Liu, Yitian Zhao, Jiong Zhang, Jonathan Lim, B. Ma, V. Romano, H. Qi, M. Ferdousi, I. Petropoulos, G. Ponirakis, S. Kaye, R. Malik, U. Alam, Yalin Zheng   +15 more
semanticscholar   +1 more source

Immortalized Schwann cell lines as useful tools for pathogenesis-based therapeutic approaches to diabetic peripheral neuropathy

Frontiers in Endocrinology
Growing evidence suggests that hyperglycemia-related abnormalities in Schwann cells play a pivotal role in the development and progression of diabetic peripheral neuropathy (DPN).
Kazunori Sango, Hideji Yako, Hideji Yako, Naoko Niimi, Shizuka Takaku   +4 more
doaj   +1 more source

The effect of a cognitive or motor task on the gait parameters of those with diabetes, with and without neuropathy [PDF]

, 2009
Aims: To compare the gait parameters of older people with diabetes (DM) and people with diabetes and diabetic peripheral neuropathy (DPN) and to investigate the effect of a secondary motor or cognitive task on their gait.
Abboud, Bond, Boulton, Bowen, Cavanagh, Courtemanche, DeMott, Dietz, Duysens, Eils, Faulkner, Folstein, Katoulis, Leinninger, MacKay-Lyons, Maurer, Menz, Mueller, Regnaux, Regnaux, Richardson, Richardson, Tilling, Wollacott, Wong, World Health Organization Study Group   +25 more
core   +1 more source

Clinical Significance of the Presence of Autonomic and Vestibular Dysfunction in Diabetic Patients with Peripheral Neuropathy [PDF]

Diabetes & Metabolism Journal, 2012
BackgroundWe investigated the prevalence of diabetic autonomic neuropathy (DAN) and vestibular dysfunction (VD) in diabetic patients with peripheral neuropathy.MethodsThirty-five diabetic patients with peripheral neuropathy were enrolled from August 2008
Soo Kyoung Kim, Kyeong Ju Lee, Jong Ryeal Hahm, Sang Min Lee, Tae Sik Jung, Jung Hwa Jung, Sungsu Kim, Deok Ryong Kim, Seong-Ki Ahn, Won-Hee Choi, Soon Il Chung   +10 more
doaj   +1 more source

The abnormal fractional amplitude of low-frequency fluctuation changes in patients with diabetic optic neuropathy: a steady-state fMRI study

Journal of Integrative Neuroscience, 2021
The spontaneous changes in brain activity in patients with diabetic optic neuropathy using steady-state fMRI. The fractional amplitude of the low-frequency fluctuation method was applied to evaluate neural activity changes.
Yi-Ping Jiang, Wen-Feng Liu, Yi-Cong Pan, Hui-Ye Shu, Li-Juan Zhang, Qiu-Yu Li, Qian-Min Ge, Rong-Bin Liang, Gang-Ming Zou, Yi Shao   +9 more
doaj   +1 more source

The paradox between resistance to hypoxia and liability to hypoxic damage in hyperglycemic peripheral nerves. Evidence for glycolysis involvement [PDF]

, 1993
Isolated ventral and dorsal rat spinal roots incubated in normal (2.5 mM) or high glucose (25 mM) concentrations or in high concentrations of other hexoses were exposed transiently to hypoxia (30 min) in a solution of low buffering power.
Grafe, Peter, Niedermeier, W., Schneider, Uwe   +2 more
core   +1 more source

Neuropathy in diabetes

Medicine, 2006
Diabetic polyneuropathy affects 30–50% of patients with diabetes mellitus. It encompasses several neuropathic syndromes, the commonest being distal symmetrical polyneuropathy or ‘diabetic peripheral neuropathy’ (DPN). Risk factors for DPN include poor glycaemic control and drivers of macrovascular disease including hypertension.
openaire   +2 more sources