Results 51 to 60 of about 878,879 (388)

Predictors of barefoot plantar pressure during walking in patients with diabetes, peripheral neuropathy and a history of ulceration [PDF]

, 2015
OBJECTIVE:Elevated dynamic plantar foot pressures significantly increase the risk of foot ulceration in diabetes mellitus. The aim was to determine which factors predict plantar pressures in a population of diabetic patients who are at high-risk of foot ...
Barn, Ruth, Bus, Sicco A., Nollet, Frans, Waaijman, Roelof, Woodburn, James   +4 more
core   +2 more sources

Clinical effectiveness and treatment satisfaction between two triple‐therapy regimens in treating neuropathic pain: A real‐world data

Ibrain, EarlyView., 2023
This study compared the clinical effectiveness and treatment satisfaction of Pregabalin and Gabapentin triple therapy for neuropathic pain in a real‐world setting. The primary outcome measured the reduction in mean Self‐Administered Leeds Assessment of Neuropathic Symptoms and Signs pain score value from baseline to 12 weeks posttreatment.
Nithya Raju, Samyuktha Villavan, Saranya Ravi, Roja Murugesan, Panneerselvam Theivendren, Vennila Jaganathan, Redlin Jani Rajan, Krupanidhi Karunanithi   +7 more
wiley   +1 more source

Diabetic peripheral neuropathy: A systematic review of Nigerian patients

Libyan International Medical University Journal, 2021
Diabetes mellitus is associated with microvascular and macrovascular complications. Diabetic neuropathy is the most common long-term complication of diabetes.
Taoreed Azeez, Emmanuel Eguzozie, Oladotun Olalusi   +2 more
doaj   +1 more source

Is resistance to ischaemia of motor axons in diabetic subjects due to membrane depolarization? [PDF]

, 1990
The reasons for the resistance to ischaemia of peripheral nerves in diabetics are not well understood. We have now explored whether axonal depolarization underlies this phenomenon, as has previously been proposed.
Baker, Barrett, Bergmans, Bergmans, Bostock, Das, Dyck, Gilliat, Greene, Gregersen, Horowitz, Hugh Bostock, Jaramillo, Klaus Piwernetz, Low, Low, Ludin, Masson, Michael Strupp, Newrick, Oh, Parry, Paul Weigl, Peter Grafe, Ritchie, Rolf Renner, Shirabe, Steiness, Steiness, Steiness, Strupp, Stöhr, Thomas, Tuck, Weigl   +34 more
core   +1 more source

An artificial intelligence-based deep learning algorithm for the diagnosis of diabetic neuropathy using corneal confocal microscopy: a development and validation study

Diabetologia, 2019
Aims/hypothesis Corneal confocal microscopy is a rapid non-invasive ophthalmic imaging technique that identifies peripheral and central neurodegenerative disease.
Bryan M. Williams, D. Borroni, Rongjun Liu, Yitian Zhao, Jiong Zhang, Jonathan Lim, B. Ma, V. Romano, H. Qi, M. Ferdousi, I. Petropoulos, G. Ponirakis, S. Kaye, R. Malik, U. Alam, Yalin Zheng   +15 more
semanticscholar   +1 more source

Diabetic Corneal Neuropathy

Journal of Clinical Medicine, 2020
Diabetic keratopathy (DK) is a common, but underdiagnosed, ocular complication of diabetes mellitus (DM) that has a significant economic burden. It is characterised by progressive damage of corneal nerves, due to DM-induced chronic hyperglycaemia and its
Hassan Mansoor, H. Tan, Molly Tzu-Yu Lin, J. Mehta, Yu-Chi Liu   +4 more
semanticscholar   +1 more source

The Effects of Co-Culturing ND7/23 Sensory Neuron-like Cells and IFRS1 Schwann Cells on Myelination: A Single-Arm Nonrandomized Study

Neurology International
Background/Objectives: Co-culture models of neurons and Schwann cells have been used to explore the mechanisms of myelination during development, axonal regeneration after injury, and the pathogenesis of various demyelinating neuropathies.
Shizuka Takaku, Kazunori Sango
doaj   +1 more source

The effects of hyperglycaemic hypoxia on rectification in rat dorsal root axons [PDF]

, 1994
1. Electrotonic responses to 150 ms current pulses were recorded from isolated rat dorsal roots incubated for at least 3 h with either normal (5 mM) or high (25 mM) D-glucose solutions, and with either normal (25 mM) or low (5 mM) bicarbonate ...
Bostock, Hugh, Grafe, Peter, Schneider, Uwe   +2 more
core   +2 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

The abnormal fractional amplitude of low-frequency fluctuation changes in patients with diabetic optic neuropathy: a steady-state fMRI study

Journal of Integrative Neuroscience, 2021
The spontaneous changes in brain activity in patients with diabetic optic neuropathy using steady-state fMRI. The fractional amplitude of the low-frequency fluctuation method was applied to evaluate neural activity changes.
Yi-Ping Jiang, Wen-Feng Liu, Yi-Cong Pan, Hui-Ye Shu, Li-Juan Zhang, Qiu-Yu Li, Qian-Min Ge, Rong-Bin Liang, Gang-Ming Zou, Yi Shao   +9 more
doaj   +1 more source