Identification of ferroptosis-related molecular clusters and genes for diabetic osteoporosis based on the machine learning [PDF]
Frontiers in Endocrinology, 2023 BackgroundDiabetic osteoporosis exhibits heterogeneity at the molecular level. Ferroptosis, a controlled form of cell death brought on by a buildup of lipid peroxidation, contributes to the onset and development of several illnesses.
Xingkai Wang +15 more
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Intermittent fasting triggers interorgan communication to improve the progression of diabetic osteoporosis [PDF]
Gut MicrobesDiabetic osteoporosis is a disease that seriously affects health, and intermittent fasting is a promising dietary approach to manage diabetes. The objective of our study was to analyze the effects of intermittent fasting on diabetic osteoporosis and its ...
Zhiyuan Guan +7 more
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Pharmacology and metabolomic reveal Polysaccharides from polygonatum sibiricum ameliorate the diabetic osteoporosis in zebrafish [PDF]
BMC Complementary Medicine and TherapiesBackground Previous studies found that Polygonatum sibiricum polysaccharide (PSP) exhibited anti-inflammatory and anti-oxidative effects on type 2 diabetes (T2DM).
Ziping Chen +9 more
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Research progress of diabetic osteoporosis: a comprehensive review [PDF]
Frontiers in EndocrinologyDiabetic osteoporosis (DOP) is a complex metabolic bone disorder characterized by impaired bone quality and increased fracture risk in patients with diabetes mellitus.
Xun Ma, Xiaoqian Zhang
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MK-4 Ameliorates Diabetic Osteoporosis in Angiogenesis-Dependent Bone Formation by Promoting Mitophagy in Endothelial Cells [PDF]
Drug Design, Development and TherapyFan Ding,1,2 Weidong Zhang,1,2 Ting Liu,1,2 Xing Rong,1,2 Yajun Cui,1,2 Lingxiao Meng,1,2 Luxu Wang,1– 3 Bo Liu,4 Minqi Li1,2,4 1Department of Bone Metabolism, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University ...
Ding F +8 more
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Cinnamaldehyde attenuates streptozocin-induced diabetic osteoporosis in a rat model by modulating netrin-1/DCC-UNC5B signal transduction [PDF]
Frontiers in PharmacologyBackground: Cinnamaldehyde (CMD) is a major functional component of Cinnamomum verum and has shown treatment effects against diverse bone diseases. This study aimed to assess the anti-diabetic osteoporosis (DOP) potential of diabetes mellitus (DM) and to
Songjie Ji +7 more
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Biochanin A abrogates osteoclastogenesis in type 2 diabetic osteoporosis via regulating ROS/MAPK signaling pathway based on integrating molecular docking and experimental validation [PDF]
BMC Complementary Medicine and TherapiesBackground There are accumulating type 2 diabetes patients who have osteoporosis simultaneously. More effective therapeutic strategies should be discovered.
Qi He +13 more
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Frontiers in Public Health, 2022 IntroductionPrevious studies based on a single measure of fasting plasma glucose (FPG) showed an inconsistent conclusion about the association between FPG and osteoporosis risk.
Ping Wang +22 more
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Editorial: The prevention and treatment of diabetic osteoporosis [PDF]
Frontiers in EndocrinologyBingzi Dong, Kexin Zhang, Chunping Zeng
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Osteoporosis, Fractures, and Diabetes [PDF]
International Journal of Endocrinology, 2014 It is well established that osteoporosis and diabetes are prevalent diseases with significant associated morbidity and mortality. Patients with diabetes mellitus have an increased risk of bone fractures. In type 1 diabetes, the risk is increased by ∼6 times and is due to low bone mass. Despite increased bone mineral density (BMD), in patients with type
Peter Jackuliak, Juraj Payer
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