Identification of ferroptosis-related molecular clusters and genes for diabetic osteoporosis based on the machine learning [PDF]
Frontiers in Endocrinology, 2023 BackgroundDiabetic osteoporosis exhibits heterogeneity at the molecular level. Ferroptosis, a controlled form of cell death brought on by a buildup of lipid peroxidation, contributes to the onset and development of several illnesses.
Xingkai Wang +15 more
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Intermittent fasting triggers interorgan communication to improve the progression of diabetic osteoporosis [PDF]
Gut MicrobesDiabetic osteoporosis is a disease that seriously affects health, and intermittent fasting is a promising dietary approach to manage diabetes. The objective of our study was to analyze the effects of intermittent fasting on diabetic osteoporosis and its ...
Zhiyuan Guan +7 more
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PPARβ/δ Agonist Alleviates Diabetic Osteoporosis via Regulating M1/M2 Macrophage Polarization
Frontiers in Cell and Developmental Biology, 2021 Diabetic osteoporosis is a common complication in diabetic patients, leading to increased fracture risk and impaired bone healing. As a member of the peroxisome proliferator-activated receptor (PPAR) family, PPARβ/δ agonist is suggested as a therapeutic ...
Miao Chen +8 more
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Pharmacology and metabolomic reveal Polysaccharides from polygonatum sibiricum ameliorate the diabetic osteoporosis in zebrafish [PDF]
BMC Complementary Medicine and TherapiesBackground Previous studies found that Polygonatum sibiricum polysaccharide (PSP) exhibited anti-inflammatory and anti-oxidative effects on type 2 diabetes (T2DM).
Ziping Chen +9 more
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Unveiling GDF-15: a new frontier in combating diabetic osteoporosis [PDF]
Frontiers in MedicineDiabetic osteoporosis (DOP) is a diabetes mellitus (DM) complication, defined by diminished bone density and a significantly increased fracture risk due to disorders in bone metabolism, making it a key clinical concern.
Nan Wang, Yingyi Gao, Ning Bai
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Research progress of diabetic osteoporosis: a comprehensive review [PDF]
Frontiers in EndocrinologyDiabetic osteoporosis (DOP) is a complex metabolic bone disorder characterized by impaired bone quality and increased fracture risk in patients with diabetes mellitus.
Xun Ma, Xiaoqian Zhang
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MK-4 Ameliorates Diabetic Osteoporosis in Angiogenesis-Dependent Bone Formation by Promoting Mitophagy in Endothelial Cells [PDF]
Drug Design, Development and TherapyFan Ding,1,2 Weidong Zhang,1,2 Ting Liu,1,2 Xing Rong,1,2 Yajun Cui,1,2 Lingxiao Meng,1,2 Luxu Wang,1– 3 Bo Liu,4 Minqi Li1,2,4 1Department of Bone Metabolism, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University ...
Ding F +8 more
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Cinnamaldehyde attenuates streptozocin-induced diabetic osteoporosis in a rat model by modulating netrin-1/DCC-UNC5B signal transduction [PDF]
Frontiers in PharmacologyBackground: Cinnamaldehyde (CMD) is a major functional component of Cinnamomum verum and has shown treatment effects against diverse bone diseases. This study aimed to assess the anti-diabetic osteoporosis (DOP) potential of diabetes mellitus (DM) and to
Songjie Ji +7 more
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Editorial: The prevention and treatment of diabetic osteoporosis [PDF]
Frontiers in EndocrinologyDong Bingzi
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Frontiers in Public Health, 2022 IntroductionPrevious studies based on a single measure of fasting plasma glucose (FPG) showed an inconsistent conclusion about the association between FPG and osteoporosis risk.
Ping Wang +22 more
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