Results 91 to 100 of about 23,869 (285)

TIMP1 regulates ferroptosis in osteoblasts by inhibiting TFRC ubiquitination: an in vitro and in vivo study

Molecular Medicine
Background In clinical practice, alterations in the internal environment of type 2 diabetes can significantly affect bone quality. While the increased risk of fractures among diabetic patients is well-established, the precise mechanisms by which ...
Bo Peng, Zhiwei Feng, Ao Yang, Jinmin Liu, Jinwen He, Lihu Xu, Cong Tian, Xiaoyun Sheng, Yaobin Wang, Rongjin Chen, Xingwen Wang, Xiaojun Ren, Bin Geng, Yayi Xia   +13 more
doaj   +1 more source

Relationship Between Biochemical Parameters and Bone Mineral Density in Postmenopausal Women of Karachi, Pakistan

Pakistan Journal of Medicine and Dentistry
 Background: Postmenopausal Osteoporosis is a significant public health concern, primarily due to estrogen decline, leading to metabolic changes and vasomotor symptoms.
Madiha Soban, Razeen Fahad, Fauzia Perveen, Tahira Assad , Amina Raza , Fasiha Fatima   +5 more
doaj   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Evaluation of bone loss in diabetic postmenopausal women

Journal of Research in Medical Sciences, 2012
Background: Osteoporosis and diabetes mellitus are major and growing public health problems particularly among postmenopausal women. This study was conducted to evaluate the relationship between osteoporosis and osteopenia with type 2 diabetes mellitus ...
Mansoor Karimifar, Morteza Aghajan Poor Pasha, Amirhossein Salari, Ahmadreza Zamani, Mansour Salesi, Peyman Motaghi   +5 more
doaj  

Biologic and Targeted Synthetic Disease‐Modifying Antirheumatic Drugs Do Not Arrest Bone Loss in Patients With Rheumatoid Arthritis: A Long‐Term Multicenter Observational Study

Arthritis &Rheumatology, EarlyView.
Objective Osteoporosis causes fractures that further increase the disease burden of rheumatoid arthritis (RA); however, osteoporosis treatment rates remain low. Although several studies have reported that biologic or targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) can prevent or improve osteoporosis in RA, our large‐scale, real ...
Takafumi Aritomi, Koshiro Sonomoto, Shingo Nakayamada, Hiroaki Tanaka, Atsushi Nagayasu, Satoshi Kubo, Ippei Miyagawa, Ayako Yamaguchi, Naoaki Ohkubo, Yasuyuki Todoroki, Yurie Satoh‐Kanda, Masanobu Ueno, Ryuichiro Kanda, Yuya Fujita, Masashi Funada, Hidenori Sakai, Satsuki Matsunaga, Hiroaki Tanaka, Masayuki Shinojima, Hiroki Kawamura, Kazuki Takahashi, Miyabi Ando, Kazuki Haru, Yusuke Miyazaki, Kentaro Hanami, Masao Nawata, Shunsuke Fukuyo, Keisuke Nakatsuka, Mikiko Tokunaga, Kazuyoshi Saito, Yoshiya Tanaka   +30 more
wiley   +1 more source

Osteoporosi e diabete mellito. [Osteoporosis and diabetes]

, 2004
Diabetes mellitus and osteoporosis are chronic diseases with an elevated and growing incidence in the elderly. Recent epidemiological studies have demonstrated an elevated risk of hip, humerus and foot fractures in elder diabetic subjects. While type 1 diabetes is generally associated with a mild reduction in bone mineral density (BMD), type 2 diabetes,
DOMINGUEZ RODRIGUEZ, Ligia Juliana, MURATORE, Maria Chiara, ZAGONE, Giovanni, BARBAGALLO M.   +3 more
openaire   +1 more source

ANK1 and EPB41 Variants and the Risk of Steroid‐Induced Osteonecrosis

Arthritis &Rheumatology, EarlyView.
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen, Xianmin Zhu, Zhongzhong Chen, Wei Chen, Hussam Alkaissi, Zeng Zhang, Yun Gao, Junhui Yin, Xiangtian Yu, Qiong Fu, Youshui Gao, Zhenzhong Zhu, Qianying Cai, Pengwei Zhang, Weibin Chen, Xin Zhao, Xiaojin Wu, Karel Pacak, Dongxu Jin, Chunde Bao, Zhengping Zhuang, Changqing Zhang   +21 more
wiley   +1 more source

Comparison of the Prevalence of Osteopenia and Osteoporosis in Postmenopausal Women with and without Type 2 Diabetes Mellitus

مجله دانشکده پزشکی اصفهان, 2014
Background: Osteoporosis and diabetes mellitus are major and growing public health problems, particularly among postmenopausal women. This study was conducted to evaluate the relationship between osteoporosis and type 2 diabetes mellitus (DM) in ...
Morteza Aghajanpoor, Amirhossein Salari, Mansoor Karimifar, Ahmadreza Zamani, Mansour Salesi, Peyman Mottaghi   +5 more
doaj  

Mind the gap: Adherence to denosumab dosing and cessation guidelines in Australian residential aged care

British Journal of Clinical Pharmacology, EarlyView.
This original research used medication administration data to explore adherence to treatment guidelines for the most common osteoporosis medications in long‐term residential aged care (RAC) in Australia. The paper highlights gaps in adherence to treatment guidelines that must be addressed to improve outcomes of older adults living in RAC.
Marea O'Donnell, Johanna I. Westbrook, Bayzidur Rahman, Isabelle Meulenbroeks, Nasir Wabe, Ian D. Cameron, Mark Morgan, Magdalena Z. Raban   +7 more
wiley   +1 more source

Effects of Type 2 Diabetic Serum on Proliferation and Osteogenic Differentiation of Mesenchymal Stem Cells

Journal of Diabetes Research, 2018
Diabetic patients have an increased risk of osteoporosis-associated fractures. However, the results of most studies of the effects of diabetes on bone mass in patients with type 2 diabetes (T2DM) have been contradictory.
Xiangqun Deng, Min Xu, Moyu Shen, Jinluo Cheng   +3 more
doaj   +1 more source