Results 141 to 150 of about 47,438 (303)

A retrospective cohort study comparing periodontal regeneration using fibroblast growth factor‐2 versus autologous bone graft

Journal of Periodontology, EarlyView.
Abstract Background Fibroblast growth factor‐2 (FGF‐2) is a novel agent utilized in periodontal regeneration therapy. However, its clinical efficacy compared with autologous bone graft (ABG), a long‐established treatment, remains unclear. This study aimed to compare the clinical outcomes of FGF‐2 and ABG and to assess the impact of patient background ...
Toshiki Matsumoto, Shin Nakamura, Yuki Ito‐Shinoda, Mai Sakamoto, Takayuki Ishii, Yasuki Nonomura, Hidetaka Ideguchi, Keisuke Okubo, Kazu Takeuchi‐Hatanaka, Kazuhiro Omori, Tadashi Yamamoto, Shogo Takashiba   +11 more
wiley   +1 more source

Role of Zinc Homeostasis in the Pathogenesis of Diabetic Osteoporosis in Mice

Diabetology
Background: Diabetes induces osteoporosis primarily by impairing osteoblast function. Intracellular zinc homeostasis, which is controlled by zinc transporters, plays a significant role in osteoblast differentiation.
Yoshinori Mizuno, Fuka Takeuchi, Marina Morimoto, Yukinori Tamura   +3 more
doaj   +1 more source

216 Jewish Hospital of St. Louis [PDF]

, 1987
https://digitalcommons.wustl.edu/bjc_216/1188/thumbnail ...

core   +1 more source

Impact of Denosumab Adherence on Renal Function and Mortality Rates in Type 2 Diabetes Patients With Osteoporosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Type 2 diabetes mellitus (T2DM) is associated with an increased risk of osteoporosis and fractures, and denosumab, a non‐kidney‐excreted antiresorptive medication, represents a viable alternative to bisphosphonates for osteoporosis treatment in patients with T2DM. This study aimed to investigate the association among denosumab adherence, renal
Yu‐Chuan Chang, Jian‐Chih Chen, Sung‐Yen Lin, Kun‐Der Lin, Pei‐Shan Ho, Chung‐Hwan Chen, Yin‐Chih Fu, Tien‐Ching Lee   +7 more
wiley   +1 more source

RTA‐408 Enhances Radiosensitivity and Inhibited Tumor Progression via JNK Pathway in Glioblastoma

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Glioblastoma (GBM) is an aggressive brain tumor with poor prognosis owing to its high invasiveness and resistance to therapy. RTA‐408, a synthetic triterpenoid and nuclear factor erythroid 2‐related factor 2 activator, exhibits anti‐inflammatory and anti‐cancer properties; however, its effects on GBM remain unclear. This study investigated the
Hung‐Pei Tsai, Hao Qin, Yoon Bin Chong, I‐Hsiang Chen, Shih‐Hsun Kuo, Tzu‐Ting Tseng, Ann‐Shung Lieu   +6 more
wiley   +1 more source

Forsythiaside A Alleviates Kidney Injury and Intestinal Epithelium Dysfunction in IgA Nephropathy by Inhibiting TLR4/NF‐κB Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley   +1 more source

Treatment Of Dop With A Dna Tetrahedron-Based Ferroptosis Inhibitor

International Dental Journal
Introduction: The aim of this study was to synthesize a functionalized ASRPFi DNA tetrahedral-based inhibitor, targeting ferroptosis and promoting bone regeneration for the treatment of diabetic osteoporosis (DOP) and fracture.
Li Yong
doaj   +1 more source

In Vivo Models of Diabetes: Unravelling Molecular Pathways in Metabolic and Skeletal Complications

Biomedicines
Background/Objectives: Diabetic osteoporosis (DOP) is a metabolic bone disorder marked by reduced bone mass, impaired microarchitecture and elevated fracture risk arising from type 1 and type 2 diabetes. Understanding its pathophysiology is essential for
Haryati Ahmad Hairi, Nor Hidayah Mustafa, Ahmad Nazrun Shuid, Muhammad Zulfiqah Sadikan   +3 more
doaj   +1 more source

Adjunctive Hyperbaric Oxygen Therapy or Intratympanic Steroids in Sudden Sensorineural Hearing Loss?

The Laryngoscope, EarlyView.
Sudden sensorineural hearing loss is traditionally treated with steroids, either orally and/or via intratympanic injections, and hyperbaric oxygen treatment (HBOT) has resurged in popularity as an adjunctive therapy. The study has not found any additional treatment benefit with adjunctive concurrent HBOT; however, HBOT might be of value to patients ...
Jennifer L. Spiegel, Michael J. De Biasio, Gianluca Sampieri, Omer J. Ungar, Munir D. Bajin, Vincent Y. W. Lin, Joseph M. Chen, Chris Idestrup, Jordan Tarshis, Trung N. Le   +9 more
wiley   +1 more source

Diabetes Mellitus and Osteoporosis

Türk Osteoporoz Dergisi, 2005
Osteoporosis is a condition of bone fragility resulting from micro-architectural deterioration and decreased bone mass. Studies on the presence of a generalized osteoporosis related to diabetes mellitus (DM) are few and controversial. Factors associated with osteoporosis diabetes in which may account for the patogenesis of diabetic bone loss have been ...
Dilek Durmuş, Turgut Topal
openaire   +1 more source