Results 221 to 230 of about 23,869 (285)

When proteases reshape barriers: Basement membrane remodelling in development, wound healing and tumour progression

The FEBS Journal, EarlyView.
Basement membrane (BM) homeostasis relies on a balance between integrity, controlled remodelling and pathological degradation. Increased protease expression beneath the BM, along with reduced levels of endogenous protease inhibitors, drives the transition from a continuous, protective barrier to a discontinuous interface.
Clara Legendre, Guila Dayan, Patricia Rousselle   +2 more
wiley   +1 more source

Diabetes and menopause: A critical yet neglected intersection

Diabetic Medicine, EarlyView.
Isabell Haage, David Studer, Petra Stute, Lia Bally   +3 more
wiley   +1 more source

Grading in Gerodontology: A Framework

Gerodontology, EarlyView.
ABSTRACT Introduction Understanding and anticipating oral health deterioration in older adults requires more than describing their current oral and general health. Risk factors arising from oral, systemic and social domains strongly influence disease progression, care complexity and the ability to maintain function over time.
Falk Schwendicke, Gerry McKenna, Frauke Müller, Azize Bell, Najla Chebib, Cristiane Da Mata, Helena Dujic, Jennifer Gallagher, Barbara Janssens, Danielle M. Layton, Manabu Kanazawa, Anastassia Kossioni, Sabrina Maniewicz, Koichiro Matsuo, Pedro Molinero Mourelle, Annika Neri, Takahiro Ono, Sungkrit Pojmonpiti, Foteini Spyraki, Kittipit Srisanoi, Saif S. Syed, Sayaka Tada, Georgios Tsakos, Terry R. Walton, W. Murray Thomson, Jean‐Philippe Haesler, Sophie Dartevelle, Murali Srinivasan   +27 more
wiley   +1 more source

Eldecalcitol ameliorates diabetic osteoporosis and glucolipid metabolic disorder by promoting Treg cell differentiation through SOCE. [PDF]

Cell Mol Life Sci
Jiang Y, Gao R, Ying Q, Li X, Dai Y, Song A, Liu H, Hasegawa T, Li M.   +8 more
europepmc   +1 more source

Associations Between Multimorbidity, Polypharmacy and Oral Conditions in Older Adults: A Systematic Review and Meta‐Analysis

Gerodontology, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis evaluated the relationship between multimorbidity and polypharmacy on the oral health in older adults (aged 75 years or older). The PECO focus question set for this study was, ‘What is the occurrence, association and impact of multimorbidity and polypharmacy on the oral conditions and its ...
Kittipit Srisanoi, Sabrina Maniewicz, Claudio Rodrigues Leles, Gerry McKenna, Frauke Müller, Murali Srinivasan   +5 more
wiley   +1 more source

Eucommia ulmoides extract regulates oxidative stress to maintain calcium homeostasis and improve diabetic osteoporosis. [PDF]

Food Sci Nutr
Shen J, Gao Y, Deng Y, Xia Z, Wang X, He X, He Y, Yang B.   +7 more
europepmc   +1 more source

Diabetes Mellitus and Osteoporosis

The Journal of Korean Diabetes, 2017
openaire   +1 more source

Italian Patients Journey for Gene Therapy in Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno, Gaia Spadarella, Alessandra Borchiellini, Anna Borrelli, Andrea Buzzi, Giancarlo Castaman, Michele Cecchi, Raimondo De Cristofaro, Vincenzo La Mura, Angelo Lupi, Giuseppe Malcangi, Maria Elisa Mancuso, Maria Francesca Mansueto, Cristina Santoro, Rita Carlotta Santoro, Luigi Piero Solimeno, Annarita Tagliaferri, Ezio Zanon, Isabella Garagiola, Flora Peyvandi   +19 more
wiley   +1 more source

Screening of active components of melastoma dodecandrum lour. against diabetic osteoporosis using cell membrane chromatography-mass spectrometry. [PDF]

Front Pharmacol
Zhang X, Mao J, Shao L, Liu S, Zhou J, Mei M, Zhang Z.   +6 more
europepmc   +1 more source

A multidisciplinary, AI‐supported quality improvement intervention to manage polypharmacy in aging people with HIV

HIV Medicine, EarlyView.
Abstract Objectives Aging people with HIV are increasingly affected by multimorbidity and polypharmacy, which heighten the risk of drug–drug interactions (DDIs) and potentially inappropriate medications (PIMs). This study evaluated a multidisciplinary, AI‐supported quality improvement intervention designed to optimize polypharmacy management in older ...
Jovana Milic, Antonia Pugliese, Michela Belli, Gian Luca Lonardi, Caterina Ruffilli, Tommaso Albano, Marco Visicaro, Martina Ricciardetto, Pierluigi De Cosmo, Chiara Mussi, Francesca Gandolfi, Cristina Mussini, Costantino Grana, Giovanni Guaraldi   +13 more
wiley   +1 more source