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Orvosi Hetilap, 2011
Over the last decades a considerable amount of data has accumulated to indicate that metabolic and endocrine alterations of diabetes affect bone quantity and quality. These skeletal changes may increase the risk of bone fracture. There is strong evidence that in type 1 diabetes the decreased bone mass, lack of insulin and insulin-like growth factor-1 ...
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Over the last decades a considerable amount of data has accumulated to indicate that metabolic and endocrine alterations of diabetes affect bone quantity and quality. These skeletal changes may increase the risk of bone fracture. There is strong evidence that in type 1 diabetes the decreased bone mass, lack of insulin and insulin-like growth factor-1 ...
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Osteoporosis-associated Fracture and Diabetes
Endocrinology and Metabolism Clinics of North America, 2014Osteoporosis and diabetes mellitus are chronic diseases with significant associated morbidity and mortality. Recent evidence suggests that both type 1 and type 2 diabetes are associated with an increased fracture risk. Fracture as a complication of diabetes must be considered when evaluating and treating patients with diabetes.
Salila, Kurra +2 more
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Osteoporosis in type II diabetes
Acta Diabetologica Latina, 1987Double photon absorptiometry comparison was done of lumbar bone mineral content (BMC) values in 40 women with well-compensated non-insulin-dependent diabetes mellitus (type II) and on dietary and/or oral hypoglycemic treatment, and 35 age-matched non-diabetic women, to determine the presence and degree of osteoporosis in this type of diabetes by means ...
G, Isaia +5 more
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2017
Accumulating evidence has shown that the risk of osteoporotic fracture is increased in patients with diabetes mellitus independently of bone mineral density. Thus, diabetes-related bone disease is now recognized as one of diabetic complications. Collagen cross-links of advanced glycation end products (AGEs), dysfunction of osteoblasts with low bone ...
Ippei Kanazawa, Toshitsugu Sugimoto
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Accumulating evidence has shown that the risk of osteoporotic fracture is increased in patients with diabetes mellitus independently of bone mineral density. Thus, diabetes-related bone disease is now recognized as one of diabetic complications. Collagen cross-links of advanced glycation end products (AGEs), dysfunction of osteoblasts with low bone ...
Ippei Kanazawa, Toshitsugu Sugimoto
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Clinical calcium, 2004
Since Albright first proposed the concept of "diabetic osteopenia", many studies have investigated the levels of bone mineral density (BMD) and the risk of osteoporosis in type 1 and type 2 diabetes. The presence of osteoporosis in type 1 diabetes seems to be a reliable evidence.
Iseki, Takamoto, Takashi, Kadowaki
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Since Albright first proposed the concept of "diabetic osteopenia", many studies have investigated the levels of bone mineral density (BMD) and the risk of osteoporosis in type 1 and type 2 diabetes. The presence of osteoporosis in type 1 diabetes seems to be a reliable evidence.
Iseki, Takamoto, Takashi, Kadowaki
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Role of microRNA in Diabetic Osteoporosis
Molecular BiotechnologyDiabetic osteoporosis (DOP), a complication associated with diabetes mellitus (DM), is a metabolic bone disorder characterized by a reduction in bone mass per unit volume, impaired bone tissue microarchitecture, heightened bone fragility, and increased susceptibility to fractures.
Qiong Yuan +5 more
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Zinc deficiency exaggerates diabetic osteoporosis
Diabetes Research and Clinical Practice, 1993Streptozotocin diabetic rats showed an increase of bone fragility (11.9 +/- 2.1 kg/cm2 vs. 16.8 +/- 2.0, P < 0.005) which was normalized by insulin treatment (18.3 +/- 4.2), indicating that osteoporosis was induced in diabetic rats. The rats were fed a zinc-deficient diet (0.16 mg/100 g) or a control diet (5.2 mg/100 g).
H, Fushimi +7 more
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Endocrinology and Metabolism Clinics of North America, 2021
G. Isanne Schacter, William D. Leslie
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G. Isanne Schacter, William D. Leslie
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Clinical calcium, 2008
The diabetes is at great risk of the osteoporosis, and the bone fragility unrelated to bone density forms the pathological conditions peculiar to diabetes. The factor participating in diabetic osteoporosis has a state of insulin action deficiency, a hyperglycemic state, diabetic complications, and so on.
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The diabetes is at great risk of the osteoporosis, and the bone fragility unrelated to bone density forms the pathological conditions peculiar to diabetes. The factor participating in diabetic osteoporosis has a state of insulin action deficiency, a hyperglycemic state, diabetic complications, and so on.
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Diabetes Mellitus and Osteoporosis
2010Diabetes mellitus (DM) is an emerging health problem for industrialized societies with substantial morbidity and mortality and an established risk factor for osteoporosis and fragility fractures.1 The skeletal alterations in patients with DM are due to insulin deficiency or resistance and hyperglycemia, alterations of the bone marrow microenvironment ...
Lorenz C. Hofbauer, Christine Hamann
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