Results 121 to 130 of about 52,017 (261)

Prospective Trial on Tolerability and Efficacy of Adjuvant Nedaplatin Plus Docetaxel for Non‐Small Cell Lung Cancer

Cancer Science, EarlyView.
The flow of this trial and the treatment schedule of adjuvant chemotherapy with nedaplatin plus docetaxel for completely resected non‐small cell lung cancer (NSCLC) (A). The primary endpoint of this study was tolerability, assessed by the completion rate of the planned four chemotherapy cycles. As a result, it was 74.3%, exceeding that reported for the
Koji Teramoto, Ryosuke Kaku, Tomoyuki Igarashi, Masayuki Hashimoto, Shoji Kitamura, Makoto Motoishi, Yuji Suzumura, Satoru Sawai, Yataro Daigo, Jun Hanaoka   +9 more
wiley   +1 more source

Bioenergetic failure in diabetic peripheral neuropathy: from glucotoxicity to multidimensional metabolic imbalance. [PDF]

J Neurol
Tao W, Yu Y, Wu X, He J, Liu X, Huang J, Xiao F, Yu R.   +7 more
europepmc   +1 more source

Diagnostic Yield and Clinical Impact of Comprehensive WES/WGS Testing Beyond Common Genetic Causes in Hereditary Optic Atrophy

Clinical Genetics, EarlyView.
Opticus atrophy—Genetic testing with WES/WGS in 62 patients with optic atrophy provided a genetic diagnosis in 21 patients (33.9%). 42.9% of these involved non‐OPA1 genes, including WFS1, ACO2, NR2F1, UCHL1, CACNA1F, and COQ2, where the genetic diagnosis prompted additional clinical evaluation, surveillance, or therapeutic intervention.
Katrine M. Johannesen, Karen Grønskov, Line Kessel, Sarah Linea von Holstein, Lisbeth Birk Møller, Mette Kjøbæk Gundestrup Andersen, Marianne Søndergaard Khinchi, Steffen Hamann, Marianne Wegener, Mette Bertelsen   +9 more
wiley   +1 more source

Therapeutic Targets, Pharmacological Mechanisms, and Delivery Strategies for Diabetic Peripheral Neuropathy. [PDF]

Drug Des Devel Ther
Wang F, Shen C, Guo W, Wang J, Xie J, Shen G, Lin Y.   +6 more
europepmc   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Smartphone-based App to Assess Diabetic Peripheral Neuropathy. [PDF]

J Diabetes Sci Technol
Adenekan RAG, Adenekan AE, Leung KK, Muppidi S, Sakamuri S, Tan M, Tsai SA, Osikomaiya M, Okamura AM, Nunez CM, Kim SH, Yoshida KT.   +11 more
europepmc   +1 more source

A systematic review of the use of artificial intelligence in mental health–based diabetes care: Current applications and future directions

Diabetic Medicine, EarlyView.
Abstract Aims To map and systematise existing research on the use of artificial intelligence (AI) in mental health–based diabetes care contexts, identify trends and potential gaps in the literature, examine methodological limitations and highlight future research directions.
Vinayak Dev, Nathan S. Consedine, Anna Boggiss, Anna Serlachius   +3 more
wiley   +1 more source

Colorectal cancer outcomes show relationships with the type and extent of vascular complications in individuals with diabetes: A population‐based study

Diabetic Medicine, EarlyView.
Abstract Aims Diabetes is associated with poorer prognosis and treatment‐related outcomes in patients with cancer. Major surgical resection is the mainstay of potentially curative treatment for colorectal cancer (CRC). This study aimed to assess whether the risk of adverse outcomes for individuals with diabetes and CRC varies by diabetes status and ...
Rebecca J. Birch, John C. Taylor, Amy Downing, Philip Quirke, Paul Finan, Katie Spencer, Eva J. A. Morris, Simon Howell, Ramzi A. Ajjan   +8 more
wiley   +1 more source

Europe's contribution to the evaluation of the use of systemic antimicrobials in the treatment of periodontitis

Periodontology 2000, EarlyView., 2023
Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera, Arie Jan van Winkelhoff, Paula Matesanz, Katalina Lauwens, Wim Teughels   +4 more
wiley   +1 more source

Lipid Signatures Associated with Diabetic Peripheral Neuropathy in Obesity and Type 2 Diabetes-A Systematic Review. [PDF]

J Clin Med
Mocanu Chitan C, Salmen T, Chitu MC, Cimpeanu RC, Clus S, Reurean-Pintilei D, Pantea Stoian A, Serafinceanu C.   +7 more
europepmc   +1 more source