Results 171 to 180 of about 52,017 (261)

Cholesterol accumulation in monocytes is associated with the severity of diabetic complications and the efficacy of glycemic control interventions in patients with type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
This study reveals that monocyte cholesterol accumulation correlates with the severity of diabetic complications and predicts post‐discharge glycemic deterioration. These findings suggest that monocytic cholesterol serves as a novel translational biomarker reflecting ‘metabolic memory’ and therapeutic resistance in patients with type 2 diabetes ...
Hideyuki Okuma, Takahiro Tsutsumi, Asako Miyazaki, Kyoichiro Tsuchiya   +3 more
wiley   +1 more source

Immunomodulatory effects of a multi-component pharmacological intervention on diabetic peripheral neuropathy in type 2 diabetic rats: An exploratory study. [PDF]

PLoS One
Zhang L, Wang S, Lei J, Zeng L, Lu A, Wu Y, Shi Y, Yang J, Yuan M, Liu H.   +9 more
europepmc   +1 more source

Improved prognosis prediction of all‐cause mortality and cardiovascular events by combined assessment of both ankle‐brachial index and brachial‐ankle pulse wave velocity in individuals with diabetes: The Kyushu prevention study for atherosclerosis, a prospective, multicenter survey

Journal of Diabetes Investigation, EarlyView.
A novel algorithm combining ABI and baPWV was developed to predict mortality and CVD risk in individuals with diabetes. This algorithm improved the accuracy of mortality and CVD risk assessment and was independent from the Framingham Risk Score. ABSTRACT Aims/Introduction People with diabetes exhibit early‐stage cardiovascular disease (CVD).
Erina Eto, Yasutaka Maeda, Noriyuki Sonoda, Hajime Nawata, Ryoichi Takayanagi, Michio Shimabukuro, Toyoshi Inoguchi   +6 more
wiley   +1 more source

Retrospective evaluation of choroidal and retinal changes in patients with diabetic peripheral neuropathy but no diabetic retinopathy. [PDF]

PeerJ
Dilek R.
europepmc   +1 more source

Type 1 diabetes‐specific distress among adults with type 1 diabetes in Japan

Journal of Diabetes Investigation, EarlyView.
This study investigated the prevalence and characteristics of diabetes distress (DD) in 117 Japanese adults with type 1 diabetes using the Type 1 Diabetes Distress Scale (T1‐DDS), PAID, and HFS. Moderate and high DD were observed in 30.8% and 16.2% of participants, respectively.
Naoki Sakane, Masayuki Domich, Akiko Suganum, Seiko Sakane   +3 more
wiley   +1 more source

Promising Biomarkers for Early Diagnosis: Advances in Understanding the Pathogenesis of Diabetic Peripheral Neuropathy. [PDF]

Diabetes Metab Syndr Obes
Lyu Q, Tan Y, Zeng X, Peng S, Lee M.
europepmc   +1 more source

Sudomotor dysfunction in people with type 1 diabetes with and without clinical peripheral neuropathy: A study from Pune, India

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Background and Aims It is appreciated that current screening tools for diabetic peripheral neuropathy (DPN) often fail to detect early disease. Sudomotor (sweat gland) dysfunction, among the earliest manifestations of DPN, can be measured objectively by the SUDOSCAN® device. We compared SUDOSCAN® with conventional validated screening (Michigan
Rohan Shah, Rishikesh Behere, Aboli Bhalerao, Sanat Phatak, Alma Baptist, Chinmay S. Marathe, Chittaranjan S. Yajnik   +6 more
wiley   +1 more source

Effectiveness of Multicomponent Balance Training and Sensorimotor Foot Mobilization on Balance and Functional Mobility in Patients With Diabetic Peripheral Neuropathy. [PDF]

Cureus
Bhawad RD, Kanase S.
europepmc   +1 more source

Hypoxia‐preconditioned adipose‐derived mesenchymal stem cells‐derived exosomes transferring H19 obstruct neutrophil extracellular traps formation via HOXA5‐mediated inactivation of TLR4/NF‐κB/NLRP3 inflammatory signaling

Journal of Diabetes Investigation, EarlyView.
In this study, we uncovered that Hypo‐Exo transferring H19 promoted diabetic wound healing by repressing NETs formation via the miR‐130a/b‐3p/HOXA5 pathway to inactivate the TLR4/NF‐κB/NLRP3 inflammatory signaling. ABSTRACT Background Hypoxia‐stimulated adipose‐derived mesenchymal stem cells (ADSCs)‐derived exosomes (Hypo‐Exo) have a positive impact on
Li Qian, Xianxi Meng, Bairong Fang, Li Pi   +3 more
wiley   +1 more source