Results 1 to 10 of about 615,781 (294)

The characteristics of pain and dysesthesia in patients with diabetic polyneuropathy. [PDF]

PLoS One, 2022
Introduction/aims Patients with diabetic polyneuropathy (DPN) may experience paresthesia, dysesthesia, and pain. We aimed to characterize the predictors, symptoms, somatosensory profile, neuropathy severity, and impact of painful DPN and dysesthetic DPN.
Gylfadottir SS, Itani M, Kristensen AG, Karlsson P, Krøigård T, Bennett DL, Tankisi H, Andersen NT, Jensen TS, Sindrup SH, Finnerup NB.   +10 more
europepmc   +9 more sources

Plasma lipid metabolites associate with diabetic polyneuropathy in a cohort with type 2 diabetes

Annals of Clinical and Translational Neurology, 2021
Objective The global rise in type 2 diabetes is associated with a concomitant increase in diabetic complications. Diabetic polyneuropathy is the most frequent type 2 diabetes complication and is associated with poor outcomes.
Amy E. Rumora, Kai Guo, Fadhl M. Alakwaa, Signe T. Andersen, Evan L. Reynolds, Marit E. Jørgensen, Daniel R. Witte, Hatice Tankisi, Morten Charles, Masha G. Savelieff, Brian C. Callaghan, Troels S. Jensen, Eva L. Feldman   +12 more
doaj   +2 more sources

RAGE activation in macrophages and development of experimental diabetic polyneuropathy. [PDF]

JCI Insight, 2022
It is suggested that activation of receptor for advanced glycation end products (RAGE) induces proinflammatory response in diabetic nerve tissues.
Osonoi S, Mizukami H, Takeuchi Y, Sugawa H, Ogasawara S, Takaku S, Sasaki T, Kudoh K, Ito K, Sango K, Nagai R, Yamamoto Y, Daimon M, Yamamoto H, Yagihashi S.   +14 more
europepmc   +2 more sources

Zinc deficiency correlates with severity of diabetic polyneuropathy. [PDF]

Brain Behav, 2021
There are controversies about the role of zinc in the development of both types 1 and 2 diabetes. The aim of this study was to assess serum zinc level in diabetic patients with and without peripheral neuropathy in comparison to healthy controls and to ...
Hussein M, Fathy W, Hassan A, Elkareem RA, Marzouk S, Kamal YS.   +5 more
europepmc   +2 more sources

Sustainable Effects of Human Dental Pulp Stem Cell Transplantation on Diabetic Polyneuropathy in Streptozotocine-Induced Type 1 Diabetes Model Mice

Cells, 2021
Dental pulp stem cells (DPSCs) are suitable for use in regenerative medicine. Cryopreserved human DPSCs (hDPSCs) ameliorate diabetic polyneuropathy, and the effects of hDPSC transplantation are related to VEGF and NGF secretion.
Masaki Hata, Maiko Omi, Yasuko Kobayashi, Nobuhisa Nakamura, Megumi Miyabe, Mizuho Ito, Tasuku Ohno, Yuka Imanishi, Tatsuhito Himeno, Hideki Kamiya, Jiro Nakamura, Hitoshi Miyachi, Shogo Ozawa, Ken Miyazawa, Akio Mitani, Toru Nagao, Shigemi Goto, Jun Takebe, Tatsuaki Matsubara, Keiko Naruse   +19 more
doaj   +2 more sources

Relationship between the progression of diabetic polyneuropathy and impaired circadian blood pressure variability [PDF]

Journal of Diabetes Investigation
Aims/Introduction We evaluated the 24‐h ambulatory blood pressure monitoring data of patients to investigate the relationship between the progression of diabetic polyneuropathy and impaired circadian blood pressure variability. Materials and Methods This
Dai Yamagami, Takahisa Deguchi, Aiko Arimura, Yoshihiko Nishio   +3 more
doaj   +2 more sources

Correlates of diabetic polyneuropathy of the elderly in Sub-Saharan Africa.

PLoS ONE, 2020
BackgroundDiabetic polyneuropathy is associated with significant physical disability among older adults. However, their frequency and correlates are not well known in the older adults in Sub-Saharan-Africa.
Nadine Simo, Callixte Kuate-Tegueu, Steve Ngankou-Tchankeu, Jacques Doumbe, Youssoufa Maiga, Matteo Cesari, Jean-François Dartigues, Andre-Pascal Kengne, Maturin Tabue-Teguo   +8 more
doaj   +2 more sources

Lumos for the long trail: Strategies for clinical diagnosis and severity staging for diabetic polyneuropathy and future directions

Journal of Diabetes Investigation, 2020
Diabetic polyneuropathy, which is a chronic symmetrical length‐dependent sensorimotor polyneuropathy, is the most common form of diabetic neuropathy. Although diabetic polyneuropathy is the most important risk factor in cases of diabetic foot, given its ...
Tatsuhito Himeno, Hideki Kamiya, Jiro Nakamura   +2 more
doaj   +2 more sources

Conditioned media from dental pulp stem cells improved diabetic polyneuropathy through anti‐inflammatory, neuroprotective and angiogenic actions: Cell‐free regenerative medicine for diabetic polyneuropathy

Journal of Diabetes Investigation, 2019
Aims/Introduction Dental pulp stem cells (DPSCs) can be easily obtained from teeth for general orthodontic reasons. We have previously reported the therapeutic effects of DPSC transplantation for diabetic polyneuropathy. As abundant secretomes from DPSCs
Eriko Makino, Nobuhisa Nakamura, Megumi Miyabe, Mizuho Ito, Saki Kanada, Masaki Hata, Tomokazu Saiki, Kazunori Sango, Hideki Kamiya, Jiro Nakamura, Ken Miyazawa, Shigemi Goto, Tatsuaki Matsubara, Keiko Naruse   +13 more
doaj   +2 more sources

Transplantation of human dental pulp stem cells ameliorates diabetic polyneuropathy in streptozotocin-induced diabetic nude mice: the role of angiogenic and neurotrophic factors

Stem Cell Research & Therapy, 2020
Background Dental pulp stem cells (DPSCs) have high proliferation and multi-differentiation capabilities that maintain their functionality after cryopreservation.
Masaki Hata, Maiko Omi, Yasuko Kobayashi, Nobuhisa Nakamura, Megumi Miyabe, Mizuho Ito, Eriko Makino, Saki Kanada, Tomokazu Saiki, Tasuku Ohno, Yuka Imanishi, Tatsuhito Himeno, Hideki Kamiya, Jiro Nakamura, Shogo Ozawa, Ken Miyazawa, Kenichi Kurita, Shigemi Goto, Jun Takebe, Tatsuaki Matsubara, Keiko Naruse   +20 more
doaj   +2 more sources