Results 21 to 30 of about 316,189 (194)

Angioblast Derived from ES Cells Construct Blood Vessels and Ameliorate Diabetic Polyneuropathy in Mice

Journal of Diabetes Research, 2015
Background. Although numerous reports addressing pathological involvements of diabetic polyneuropathy have been conducted, a universally effective treatment of diabetic polyneuropathy has not yet been established.
Tatsuhito Himeno, Hideki Kamiya, Keiko Naruse, Zhao Cheng, Sachiko Ito, Taiga Shibata, Masaki Kondo, Jiro Kato, Tetsuji Okawa, Atsushi Fujiya, Hirohiko Suzuki, Tetsutaro Kito, Yoji Hamada, Yutaka Oiso, Kenichi Isobe, Jiro Nakamura   +15 more
doaj   +1 more source

Treatment of Diabetic Sensory Polyneuropathy [PDF]

Current Treatment Options in Neurology, 2011
No current disease-modifying treatments have been shown definitively in randomized clinical trials to reduce or reverse diabetic sensory polyneuropathy (DSP). It is increasingly recognized that individuals with "prediabetes" or impaired glucose regulation can already have a "small-fiber" neuropathy, or mild DSP, in which sensory axons of both small and
Lindsay, Zilliox, James W, Russell
openaire   +2 more sources

Relationship between the Diabetic Polyneuropathy Index and the Neurological Findings of Diabetic Polyneuropathy

Internal Medicine, 2020
Objective To achieve an accurate quantification in diabetic polyneuropathy (DPN), we developed a new electrophysiological index that we called the DPN index. The relationship between the DPN index and the neurological findings in diabetic patients was assessed.
Hemmi, Shoji, Kurokawa, Katsumi, Nagai, Taiji, Yokoi, Keiichi, Okamoto, Toshio, Asano, Akio, Murakami, Tatsufumi, Mihara, Masahito, Sunada, Yoshihide   +8 more
openaire   +3 more sources

Alpha-Lipoic Acid for the Prevention of Diabetic Macular Edema [PDF]

, 2011
Introduction: To evaluate the effect of alpha-lipoic acid (ALA) on the occurrence of diabetic macular edema. Methods: Randomized, double-blind, placebo-controlled, multicenter, multinational study. Patients were randomized to the treatment group with 600
Haritoglou, Christos, Anselm Kampik, Joachim Gerss, Gerss, Joachim, Hammes, Hans P., Ulbig, Michael W., null null, Christos Haritoglou, Kampik, Anselm, Hans P. Hammes, Michael W. Ulbig   +10 more
core   +1 more source

Relation between Serum Uric Acid and Peripheral Neuropathy in Cases of Type 2 Diabetes Mellitus [PDF]

International Journal of Medical Arts, 2023
Background: Peripheral neuropathy is a common sequel of diabetes mellitus type 2, and may occur as an initial manifestation of diabetes. The role of uric acid in diabetic neuropathy as a microvascular complication of diabetes type 2 has been reported in ...
Hossam Ali, Ahmed Al-Adl
doaj   +1 more source

DIABETIC POLYNEUROPATHY;

The Professional Medical Journal, 2008
Introduction: Diabetes mellitus with the prevalence rate of 8.9-12.3% in human population,ultimately leads to the peripheral nervous system involvement in many patients. It causes various types ofpolyneuropathies which may manifest abnormalities such as impaired nerve conduction velocity (NCV) and prolongedF-wave latency.
NASER ZANGIABADI, MD, MOHAMAD NAEIM AHRARI, MD, NOUZAR NAKHAEE, MD   +2 more
openaire   +2 more sources

A brain-based pain facilitation mechanism contributes to painful diabetic polyneuropathy [PDF]

, 2018
The descending pain modulatory system represents one of the oldest and most fundamentally important neurophysiological mechanisms relevant to pain. Extensive work in animals and humans has shown how a functional imbalance between the facilitatory and ...
Segerdahl, Andrew, David L Bennett, Bennett, DL, Andreas C Themistocleous, Irene Tracey, Tracey, I, Themistocleous, Andreas C., Bennett, David L., Segerdahl, AR, Tracey, Irene, Fido, D, Fido, Dean, Andrew R Segerdahl, Dean Fido, Segerdahl, Andrew R., Themistocleous, AC   +15 more
core   +1 more source

Transplantation of dental pulp stem cells improves long-term diabetic polyneuropathy together with improvement of nerve morphometrical evaluation

Stem Cell Research & Therapy, 2017
Background Although previous reports have revealed the therapeutic potential of stem cell transplantation in diabetic polyneuropathy, the effects of cell transplantation on long-term diabetic polyneuropathy have not been investigated.
Maiko Omi, Masaki Hata, Nobuhisa Nakamura, Megumi Miyabe, Shogo Ozawa, Hitoshi Nukada, Masami Tsukamoto, Kazunori Sango, Tatsuhito Himeno, Hideki Kamiya, Jiro Nakamura, Jun Takebe, Tatsuaki Matsubara, Keiko Naruse   +13 more
doaj   +1 more source

The relation between serum uric acid levels and diabetic peripheral neuropathy in type 2 diabetes in Guilan, north of Iran

BMC Endocrine Disorders, 2022
Background Diabetic peripheral neuropathy (DPN) is one of the most common chronic microvascular complications in type 2 diabetes mellitus (T2DM). Hence, the present study aimed to investigate the association between Serum Uric Acid (SUA) levels and ...
Haniye Sadat Fayazi, Maryam Yaseri, Seyyede Sahere Mortazavi, Zahra Sharifhassan, Ali-Sina Assadinia   +4 more
doaj   +1 more source

Neurobiological Opportunities in Diabetic Polyneuropathy

Neurotherapeutics, 2021
This review highlights a selection of potential translational directions for the treatment of diabetic polyneuropathy (DPN) currently irreversible and without approved interventions beyond pain management. The list does not include all diabetic targets that have been generated over several decades of research but focuses on newer work.
Trevor M. Poitras, Easton Munchrath, Douglas W. Zochodne   +2 more
openaire   +2 more sources