Antioxidant response and neurotransmitter modulation driven by oleuropein/alpha-lipoic acid attenuates lead-induced reproductive toxicity and neurotoxicity in Drosophila melanogaster [PDF]
BMC Pharmacology and ToxicologyLead is a ubiquitous environmental and industrial toxicant known to cause reproductive toxicity and neurotoxicity via the induction of oxidative damage and modulation of neurotransmitters.
Ebenezer Adeola Ashamu +9 more
doaj +2 more sources
Animals, 2021 Alpha-lipoic acid (a-LA) is used as a nutritive additive in dog food. Therefore, we performed a systematic review of studies published to date in PubMed, Google Scholar, Cochrane Library and MedlinePlus involving alpha-lipoic acid supplementation, which ...
Reshma M. Anthony +2 more
doaj +3 more sources
In Silico and In Vitro Investigation of Apoptosis-Mediated Antiproliferative Activity of Capsaicin and Alpha-Lipoic Acid Against Prostate Cancer Cells [PDF]
Current Issues in Molecular BiologyNatural products are widely used in the treatment of cancer due to the side effects of chemotherapeutics, and a large number of natural compounds have been reported to have anticancer activities in different types of cancer.
Ogunc Meral +9 more
doaj +2 more sources
B-ENT, 2022 Objective: Alpha-lipoic acid is an antioxidant agent with potential anti-inflammatory properties and is produced from octanoic acid. The aim of this study was to investigate the effects of alpha-lipoic acid on inflammation, oxidative status, tissue ...
Nihal Efe Atila +10 more
doaj +4 more sources
Synergistic antihyperglycemic effect of alpha lipoic acid with antidiabetic agents in the normoglycemic and streptozotocin-induced type 2 diabetic rats [PDF]
Acta Poloniae Pharmaceutica, 2023 The current study's main goal was to assess the supplementation effect of alpha lipoic acid with antidiabetic medications (metformin and sitagliptin) on normal and streptozotocin-induced blood glucose levels in normal and streptozotocin-induced diabetic ...
Rawsan Ali Sabri +2 more
doaj +1 more source
SVU-International Journal of Veterinary Sciences, 2022 Background: Pharmacological and toxicological challenges are among the most important studies in revealing the latent properties of drugs Objective: the goal of this study was to evaluate the effects of alpha-lipoic acid on the central nervous system ...
Marwa Abdul-Ghani, Ahmed Naser
doaj +1 more source
Endocrinology Research and Practice, 2021 Anti-insulin antibody syndrome is a rare autoimmune disorder that is characterized by severe hypoglycemia, elevated blood insulin level, insulin autoantibodies, and the absence of pancreas islet cell pathology or exogenous insulin exposure.
Emine KARTAL BAYKAN
doaj +1 more source
Effect of Alpha-Lipoic Acid on the Characteristics and Physical Stability of NLC-Green Tea Extract
Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2022 Background: The addition of alpha-lipoic acid in Nanostructured Lipid Carrier-Green Tea Extract (NLC-GTE) has potential to increase effectiveness of anti-aging preparations.
Fairuz Yaumil Afra +2 more
doaj +1 more source
The protective impacts of lipoic acid on diclofenac-induced hepatorenal toxicity in broiler chicks [PDF]
Iraqi Journal of Veterinary Sciences, 2022 Alpha-lipoic acid is an anti-inflammatory and antioxidant compound that shows free radical scavenging actions and potent antioxidant properties on the metabolites of other cellular oxidants.
Marwa R. Abdul-Ghani, Ahmed S. Naser
doaj +1 more source
Biochemical study on the effect of alpha-lipoic acid on lipid metabolism of rats fed high fat diet [PDF]
Benha Veterinary Medical Journal, 2015 Hyperlipidemia is a known risk factor for the development of cardiovascular disease includingatherosclerosis. The present study was carried to evaluate the protective effects of alpha-lipoic acidagainst hyperlipidemia induced in rats fed high fat diet ...
Ahmed Abu-ghazalla +2 more
doaj +1 more source