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Diabetes and alpha lipoic acid [PDF]
Frontiers in Pharmacology, 2011 Diabetes mellitus is a multi-faceted metabolic disorder where there is increased oxidative stress that contributes to the pathogenesis of this debilitating disease.
Issy eLaher
doaj +3 more sources
Alpha-lipoic acid for diabetic peripheral neuropathy. [PDF]
Cochrane Database Syst Rev, 2018 Diabetic peripheral neuropathy (DPN) is a frequent complication in people living with type 1 or type 2 diabetes. There is currently no effective treatment for DPN. Although alpha-lipoic acid (ALA, also known as thioctic acid) is widely used, there is no consensus about its benefits and harms.To assess the effects of alpha-lipoic acid as a disease ...
Baicus C +4 more
europepmc +4 more sources
Toxicology Reports, 2018 This study was carried out to determine the changes in the lungs of the rat pups exposed to tobacco smoke during pregnancy period and to investigate the protective effects of alpha lipoic acid, which is administered during pregnancy, on these changes ...
Elif Erdem Guzel +5 more
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Alpha-Lipoic Acid: Biological Mechanisms and Health Benefits. [PDF]
Antioxidants (Basel)Alpha-lipoic acid (ALA) is a bioactive molecule with significant health effects. The biological action of ALA has been ascribed to the characteristic antioxidant properties of the oxidized form (ALA) and its reduced counterpart the dihydrolipoic acid (DHLA) system.
Superti F, Russo R.
europepmc +4 more sources
Synergistic antihyperglycemic effect of alpha lipoic acid with antidiabetic agents in the normoglycemic and streptozotocin-induced type 2 diabetic rats [PDF]
Acta Poloniae Pharmaceutica, 2023 The current study's main goal was to assess the supplementation effect of alpha lipoic acid with antidiabetic medications (metformin and sitagliptin) on normal and streptozotocin-induced blood glucose levels in normal and streptozotocin-induced diabetic ...
Rawsan Ali Sabri +2 more
doaj +1 more source
SVU-International Journal of Veterinary Sciences, 2022 Background: Pharmacological and toxicological challenges are among the most important studies in revealing the latent properties of drugs Objective: the goal of this study was to evaluate the effects of alpha-lipoic acid on the central nervous system ...
Marwa Abdul-Ghani, Ahmed Naser
doaj +1 more source
Endocrinology Research and Practice, 2021 Anti-insulin antibody syndrome is a rare autoimmune disorder that is characterized by severe hypoglycemia, elevated blood insulin level, insulin autoantibodies, and the absence of pancreas islet cell pathology or exogenous insulin exposure.
Emine KARTAL BAYKAN
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The protective impacts of lipoic acid on diclofenac-induced hepatorenal toxicity in broiler chicks [PDF]
Iraqi Journal of Veterinary Sciences, 2022 Alpha-lipoic acid is an anti-inflammatory and antioxidant compound that shows free radical scavenging actions and potent antioxidant properties on the metabolites of other cellular oxidants.
Marwa R. Abdul-Ghani, Ahmed S. Naser
doaj +1 more source
Animals, 2021 Alpha-lipoic acid (a-LA) is used as a nutritive additive in dog food. Therefore, we performed a systematic review of studies published to date in PubMed, Google Scholar, Cochrane Library and MedlinePlus involving alpha-lipoic acid supplementation, which ...
Reshma M. Anthony +2 more
doaj +1 more source
Effect of Alpha-Lipoic Acid on the Characteristics and Physical Stability of NLC-Green Tea Extract
Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2022 Background: The addition of alpha-lipoic acid in Nanostructured Lipid Carrier-Green Tea Extract (NLC-GTE) has potential to increase effectiveness of anti-aging preparations.
Fairuz Yaumil Afra +2 more
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