B-ENT, 2022 Objective: Alpha-lipoic acid is an antioxidant agent with potential anti-inflammatory properties and is produced from octanoic acid. The aim of this study was to investigate the effects of alpha-lipoic acid on inflammation, oxidative status, tissue ...
Nihal Efe Atila +10 more
doaj +2 more sources
Biochemical study on the effect of alpha-lipoic acid on lipid metabolism of rats fed high fat diet [PDF]
Benha Veterinary Medical Journal, 2015 Hyperlipidemia is a known risk factor for the development of cardiovascular disease includingatherosclerosis. The present study was carried to evaluate the protective effects of alpha-lipoic acidagainst hyperlipidemia induced in rats fed high fat diet ...
Ahmed Abu-ghazalla +2 more
doaj +1 more source
Alpha-Lipoic Acid and Diabetic Neuropathy [PDF]
The Review of Diabetic Studies, 2009 Diabetic neuropathy presents a major public health problem. It is defined by the symptoms and signs of peripheral nerve dysfunction in diabetic patients, in whom other causes of neuropathy have been excluded. Pathogenetic mechanisms that have been implicated in diabetic neuropathy are: a) increased flux through the polyol pathway, leading to ...
Natalia, Vallianou +2 more
openaire +2 more sources
Attenuating Effect of Spirulina Platensis and Alpha-lipoic acid against Aspartame induced Oxidative stress and Brain damage in Rabbits [PDF]
Benha Veterinary Medical Journal, 2019 Spirulina and lipoic acid has been considered as one of the most effective in anti- oxidative stress and anti-inflammatory activity.Aspartame (ASP) is one of the mostwidely used (artificial sweeteners)used in a variety of foods and feeds.This study was ...
Mahamoud Arafa +3 more
doaj +1 more source
Spirulina platensis and alpha lipoic acid are protective against the deleterious effects of aspartame on the liver and kidneys of rabbits [PDF]
Benha Veterinary Medical Journal, 2019 Spirulina platensis and alpha lipoic acid are the most important antioxidants. The purpose of this study was to explore the adverse effect of artificial sweetener (Aspartame) and the protective role of alpha lipoic acid and spirulina in alleviating the ...
Samy Hussein +3 more
doaj +1 more source
Activity of serum paraoxonase 1, lipid profile and atherogenic indexes in diabetic induced rats treated with alpha lipoic acid [PDF]
Journal of Nephropathology, 2018 Background: Paraoxonase 1 (PON1) is an enzyme attached to high density lipoprotein (HDL-C) which has antioxidant and anti-atherogenic activities. Objectives: In this study, we investigated the effects of alpha lipoic acid on PON1 activity, lipid profile ...
Parisa Jamor +3 more
doaj +1 more source
Estimation of pharmacokinetic parameters of alpha-lipoic acid in the chicks model
Baghdad Journal of Biochemistry and Applied Biological Sciences, 2022 Background and objective: Alpha-lipoic acid is a drug used to treat diabetic neuropathy, and it has other uses as a dietary supplement. The target of the study was to investigate the concentration of therapeutic doses of Alpha-lipoic acid in the blood ...
Marwa R. Abdulghani, Ahmed S. Naser
doaj +1 more source
Experimental Study of the Possible Protective Effect of Alpha-Lipoic Acid on Paracetamol induced Oxidative Stress and Hepatic Toxicity in albino rats [PDF]
Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 2021 Background: Paracetamol, is the most widely used over-the-counter analgesic and antipyretic medication in the world, which has minimal adverse effects at therapeutic dosages. But in high doses causes hepatic damage and oxidative stress.
Maha Hilal +4 more
doaj +1 more source
Role of Alpha Lipoic Acid on Cyclophosphamide Induced Cardiotoxicity in Adult Male Albino Rat: Histological Study [PDF]
The Egyptian Journal of Histology, 2019 Background: Cyclophosphamide is a chemotherapeutic agent used for treatment of leukemia, lymphoma and myeloma. Several studies reported wide range of cyclophosphamide induced cardiotoxicity in cancerous patients.
manar bashandy, omyma zedan
doaj +1 more source
Качественная клиническая практика, 2021 Rational pharmacotherapy in the Program of Preferential Medicinal Providing can be implemented subject to high-quality information support from healthcare professionals.
E. V. Eliseeva +4 more
doaj +1 more source