Alpha lipoic acid in obstetrics and gynecology
Gynecological Endocrinology, 2018 Alpha-Lipoic acid (ALA) is a natural antioxidant synthetized by plants and animals, identified as a catalytic agent for oxidative decarboxylation of pyruvate and α-ketoglutarate. In this review, we analyzed the action of ALA in gynecology and obstetrics focusing in particular on neuropathic pain and antioxidant and anti-inflammatory action.
Di Tucci, Chiara +7 more
openaire +5 more sources
Evaluation of the neuroprotective effects of alpha lipoic acid-loaded folate-conjugated chitosan nanoparticles against 6-OHDA-induced apoptosis and oxidative stress in an in vitro Parkinson's disease model. [PDF]
BMC NeurosciGheybi E +5 more
europepmc +2 more sources
Estimation of pharmacokinetic parameters of alpha-lipoic acid in the chicks model
Baghdad Journal of Biochemistry and Applied Biological Sciences, 2022 Background and objective: Alpha-lipoic acid is a drug used to treat diabetic neuropathy, and it has other uses as a dietary supplement. The target of the study was to investigate the concentration of therapeutic doses of Alpha-lipoic acid in the blood ...
Marwa R. Abdulghani, Ahmed S. Naser
doaj +1 more source
Качественная клиническая практика, 2021 Rational pharmacotherapy in the Program of Preferential Medicinal Providing can be implemented subject to high-quality information support from healthcare professionals.
E. V. Eliseeva +4 more
doaj +1 more source
Activity of serum paraoxonase 1, lipid profile and atherogenic indexes in diabetic induced rats treated with alpha lipoic acid [PDF]
Journal of Nephropathology, 2018 Background: Paraoxonase 1 (PON1) is an enzyme attached to high density lipoprotein (HDL-C) which has antioxidant and anti-atherogenic activities. Objectives: In this study, we investigated the effects of alpha lipoic acid on PON1 activity, lipid profile ...
Parisa Jamor +3 more
doaj +1 more source
Alpha-Lipoic Acid Is an Effective Nutritive Antioxidant for Healthy Adult Dogs
Animals, 2021 This study was designed to determine the effect of alpha-lipoic acid on the glutathione status in healthy adult dogs. Following a 15 month baseline period during which dogs were fed a food containing no alpha-lipoic acid, dogs were randomly allocated ...
Reshma M. Anthony +4 more
doaj +1 more source
Cell & Bioscience, 2011 Haloperidol is an antipsychotic drug that exerts its' antipsychotic effects by inhibiting dopaminergic neurons. Although the exact pathophysiology of haloperidol extrapyramidal symptoms are not known, the role of reactive oxygen species in inducing ...
Perera Joachim +4 more
doaj +1 more source
The Application of Lipoic Acid in Experimentally Induced Tympanosclerosis in Rats
Journal of Contemporary Medicine, 2020 Background/Aims:Tympanosclerosis is an abnormal tissue reaction resulting in sclerotic and hyalinization changes in the tympanic membrane and middle ear.
Fatih Turan +2 more
doaj +1 more source
Autoimmune hypoglycemia due to alpha-lipoic acid: Report of two cases.
J Postgrad MedSubramaniam K, Tom B.
europepmc +2 more sources
Alpha-Lipoic Acid and Diabetic Neuropathy [PDF]
The Review of Diabetic Studies, 2009 Diabetic neuropathy presents a major public health problem. It is defined by the symptoms and signs of peripheral nerve dysfunction in diabetic patients, in whom other causes of neuropathy have been excluded. Pathogenetic mechanisms that have been implicated in diabetic neuropathy are: a) increased flux through the polyol pathway, leading to ...
Natalia, Vallianou +2 more
openaire +2 more sources