Results 11 to 20 of about 3,275,969 (247)
Diabetes and alpha lipoic acid [PDF]
Frontiers in Pharmacology, 2011 Diabetes mellitus is a multi-faceted metabolic disorder where there is increased oxidative stress that contributes to the pathogenesis of this debilitating disease.
Issy eLaher
doaj +7 more sources
In Silico and In Vitro Investigation of Apoptosis-Mediated Antiproliferative Activity of Capsaicin and Alpha-Lipoic Acid Against Prostate Cancer Cells [PDF]
Current Issues in Molecular BiologyNatural products are widely used in the treatment of cancer due to the side effects of chemotherapeutics, and a large number of natural compounds have been reported to have anticancer activities in different types of cancer.
Ogunc Meral +9 more
doaj +2 more sources
Neuroprotective Effects of Alpha Lipoic Acid on Haloperidol-Induced Oxidative Stress in the Rat Brain [PDF]
Cell & Bioscience, 2011 Haloperidol is an antipsychotic drug that exerts its' antipsychotic effects by inhibiting dopaminergic neurons. Although the exact pathophysiology of haloperidol extrapyramidal symptoms are not known, the role of reactive oxygen species in inducing ...
Perera Joachim +4 more
doaj +2 more sources
Alpha lipoic acid in obstetrics and gynecology
Gynecological Endocrinology, 2018 Alpha-Lipoic acid (ALA) is a natural antioxidant synthetized by plants and animals, identified as a catalytic agent for oxidative decarboxylation of pyruvate and α-ketoglutarate. In this review, we analyzed the action of ALA in gynecology and obstetrics focusing in particular on neuropathic pain and antioxidant and anti-inflammatory action.
Pierluigi Benedetti Panici +2 more
exaly +4 more sources
Dihydro-alpha-lipoic acid has more potent cytotoxicity than alpha-lipoic acid
In Vitro Cellular and Developmental Biology - Animal, 2009 Alpha-lipoic acid has been shown to possess cancer-cell-killing activity via activation of the apoptosis pathway. In this study, the cytotoxic activities of alpha-lipoic and dihydro-alpha-lipoic acid were compared in HL-60 cells. The cell-killing activity of dihydro-alpha-lipoic acid was higher than that of alpha-lipoic acid.
Masao Yamasaki +2 more
exaly +5 more sources
Alpha-lipoic acid drugs in the treatment of diabetic neuropathy
Медицинский совет, 2014 Diabetic neuropathy is the most common complication of diabetes mellitus. Among the large number of drugs used as symptomatic therapy to reduce its manifestations, alpha-lipoic acid medications are specific for providing pathogenic effect on many ...
L. Y. Morgunov
doaj +2 more sources
Synergistic antihyperglycemic effect of alpha lipoic acid with antidiabetic agents in the normoglycemic and streptozotocin-induced type 2 diabetic rats [PDF]
Acta Poloniae Pharmaceutica, 2023 The current study's main goal was to assess the supplementation effect of alpha lipoic acid with antidiabetic medications (metformin and sitagliptin) on normal and streptozotocin-induced blood glucose levels in normal and streptozotocin-induced diabetic ...
Rawsan Ali Sabri +2 more
doaj +1 more source
SVU-International Journal of Veterinary Sciences, 2022 Background: Pharmacological and toxicological challenges are among the most important studies in revealing the latent properties of drugs Objective: the goal of this study was to evaluate the effects of alpha-lipoic acid on the central nervous system ...
Marwa Abdul-Ghani, Ahmed Naser
doaj +1 more source
Endocrinology Research and Practice, 2021 Anti-insulin antibody syndrome is a rare autoimmune disorder that is characterized by severe hypoglycemia, elevated blood insulin level, insulin autoantibodies, and the absence of pancreas islet cell pathology or exogenous insulin exposure.
Emine KARTAL BAYKAN
doaj +1 more source
Animals, 2021 Alpha-lipoic acid (a-LA) is used as a nutritive additive in dog food. Therefore, we performed a systematic review of studies published to date in PubMed, Google Scholar, Cochrane Library and MedlinePlus involving alpha-lipoic acid supplementation, which ...
Reshma M. Anthony +2 more
doaj +1 more source