Effect of Alpha-Lipoic Acid on the Characteristics and Physical Stability of NLC-Green Tea Extract
Background: The addition of alpha-lipoic acid in Nanostructured Lipid Carrier-Green Tea Extract (NLC-GTE) has potential to increase effectiveness of anti-aging preparations.
Fairuz Yaumil Afra +2 more
doaj +1 more source
The protective impacts of lipoic acid on diclofenac-induced hepatorenal toxicity in broiler chicks [PDF]
Alpha-lipoic acid is an anti-inflammatory and antioxidant compound that shows free radical scavenging actions and potent antioxidant properties on the metabolites of other cellular oxidants.
Marwa R. Abdul-Ghani, Ahmed S. Naser
doaj +1 more source
Protective Effects of Alpha Lipoic Acid Against Ionizing Radiation- Induced Hepatotoxicity in Rats
Objective: Radiation is used to treat cancer but causes serious complications, such as liver toxicity. In this study, the protective effects of alpha lipoic acid against the unwanted effects of radiation used in many cancer treatments which can cause ...
Laloğlu, Abubekir +5 more
core +1 more source
Alpha-Lipoic Acid for the Prevention of Diabetic Macular Edema [PDF]
Introduction: To evaluate the effect of alpha-lipoic acid (ALA) on the occurrence of diabetic macular edema. Methods: Randomized, double-blind, placebo-controlled, multicenter, multinational study. Patients were randomized to the treatment group with 600
Haritoglou, Christos +10 more
core +1 more source
Apicoplast lipoic acid protein ligase B is not essential for Plasmodium falciparum [PDF]
Lipoic acid (LA) is an essential cofactor of α-keto acid dehydrogenase complexes (KADHs) and the glycine cleavage system. In Plasmodium, LA is attached to the KADHs by organelle-specific lipoylation pathways.
Ryan Bissett +48 more
core +1 more source
Knockout studies reveal an important role of plasmodium lipoic acid protein ligase a1 for asexual blood stage parasite survival [PDF]
Lipoic acid (LA) is a dithiol-containing cofactor that is essential for the function of a-keto acid dehydrogenase complexes. LA acts as a reversible acyl group acceptor and 'swinging arm' during acyl-coenzyme A formation.
Sylke Müller +12 more
core +2 more sources
Alpha-Lipoic Acid Is an Effective Nutritive Antioxidant for Healthy Adult Dogs
This study was designed to determine the effect of alpha-lipoic acid on the glutathione status in healthy adult dogs. Following a 15 month baseline period during which dogs were fed a food containing no alpha-lipoic acid, dogs were randomly allocated ...
Reshma M. Anthony +4 more
doaj +1 more source
Alpha lipoic acid for dementia
BACKGROUND: Oxidative processes have been implicated in the pathogenesis of neurodegenerative dementias including Alzheimer's disease. Protecting the central nervous system against these damaging mechanisms may be a useful therapeutic approach.
Tabet, N, Sauer, J, Howard, R
core +5 more sources
Background: cyclophosphamide is an immunosuppressive agent and anticancer drug in childhood and adult malignant tumors. The compounds that have antioxidant properties might improve the side effect of cyclophosphamide on spermatogenesis.
Hanan Elkerdasy
doaj +1 more source
AMELIORATIVE ROLE OF ALPHA LIPOIC ACID ON PARACETAMOL INDUCED RENAL TOXICITY AND OXIDATIVE STRESS IN RATS [PDF]
Background: Paracetamol, is the most widely used over-the-counter analgesic and antipyretic medication in the world, which has no adverse effect at therapeutic dosages. But in high doses causes renal failure. Objectives: The current study was designed to
sheren mahmoud +4 more
doaj +1 more source

