Results 21 to 30 of about 13,774 (240)

Alpha-lipoic acid reduces body weight and regulates triglycerides in obese patients with diabetes mellitus [PDF]

open access: yesMedicinski Glasnik, 2015
Aim To determine an influence of alpha-lipoic acid to reduction of body weight and regulation of total cholesterol concentration, triglycerides and glucose serum levels in obese patients with diabetes mellitus type 2.
Azra Okanović   +3 more
doaj   +1 more source

Dietary Alpha-Lipoic Acid Alters Piglet Neurodevelopment [PDF]

open access: yesFrontiers in Pediatrics, 2016
Alpha-lipoic acid (a-LA) is an antioxidant shown to ameliorate age-associated impairments of brain and cardiovascular function. Human milk is known to have high antioxidant capacity; however, the role of antioxidants in the developing brain is largely uncharacterized.
Austin T Mudd   +7 more
openaire   +3 more sources

Effects of Silver Nanoparticles on the Ovarian Tissue of NMRI Rats Treated with Alpha Lipoic Acid: A Stereological Study [PDF]

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2023
Background and Objective: Silver nanoparticles are produced in large quantities in the industry and have estrogenic activities and toxic effects on different organs.
Seyed Mohammad Ali Shariatzadeh   +2 more
doaj  

Flurbiprofen: Determination of safety profile, analgesic effect, and interaction with lipoic acid in murine [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2023
our study aimed study aimed to detect and investigate the safety profile of flurbiprofen and evaluate the analgesic effects of the tail immersion and writhing tests, as well as its interaction with lipoic acid as an analgesic for visceral pain in mice ...
Naktal M. Alberifki, Ahmed S. Naser
doaj   +1 more source

Dihydro-alpha-lipoic acid has more potent cytotoxicity than alpha-lipoic acid

open access: yesIn Vitro Cellular & Developmental Biology - Animal, 2009
Alpha-lipoic acid has been shown to possess cancer-cell-killing activity via activation of the apoptosis pathway. In this study, the cytotoxic activities of alpha-lipoic and dihydro-alpha-lipoic acid were compared in HL-60 cells. The cell-killing activity of dihydro-alpha-lipoic acid was higher than that of alpha-lipoic acid.
Masao, Yamasaki   +9 more
openaire   +3 more sources

Safety and Efficacy of Alpha Lipoic Acid During 4 Years of Observation: A Retrospective, Clinical Trial in Healthy Subjects in Primary Prevention

open access: yesDrug Design, Development and Therapy, 2020
Giuseppe Derosa,1,2 Angela D’Angelo,2 Paola Preti,1 Pamela Maffioli1 1Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy; 2Laboratory of Molecular Medicine, University of Pavia, Pavia, ItalyCorrespondence: Giuseppe ...
Derosa G   +3 more
doaj  

Efficacy of the R(+)-enantiomer of alpha-lipoic acid in clinical practice

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2021
The article presents current data from the scientific medical literature on the effective use of the R(+)-enantiomer of α-lipoic acid in various pathological conditions.
N.О. Kravchun, I.P. Dunaieva
doaj   +1 more source

A dual action of alpha-lipoic acid in the brain: an electrophysiological evaluation [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2003
Oxidative stress causes metabolic and structural abnormalities during reperfusion. In an animal model of electrophysiological evaluation of cerebral ischemia-reperfusion, alpha-lipoic acid effect on the oxidative stress was studied by mean absolute ...
Otoni Cardoso do Vale   +3 more
doaj  

Studying the Effect of Adding Alpha Lipoic Acid to Gabapentin to Improve Nerve Conduction Velocity and Glycemic Control of Patients with Diabetic Neuropathy (Sample of Iraqi population)

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2020
Diabetic neuropathy (DN) is the most common chronic complication of diabetes mellitus. Hyperglycemia-induced oxidative stress induces programmed cell death of nerves, which contributes to the pathology of Diabetic neuropathy. Many clinical trials depend
Rusul AbdulKareem Hadi   +2 more
doaj   +1 more source

α-Lipoic Acid and Cardiovascular Disease [PDF]

open access: yesThe Journal of Nutrition, 2003
Alpha-lipoic acid (ALA) has been identified as a powerful antioxidant found naturally in our diets, but appears to have increased functional capacity when given as a supplement in the form of a natural or synthetic isolate. ALA and its active reduced counterpart, dihydrolipoic acid (DHLA), have been shown to combat oxidative stress by quenching a ...
Stephanie D, Wollin, Peter J H, Jones
openaire   +2 more sources

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