Results 31 to 40 of about 13,774 (240)
Clinical Approaches to the Treatment of Diabetic Neuropathy
Mìžnarodnij Endokrinologìčnij Žurnal, 2014 The article is devoted to the treatment of diabetic neuropathy. The described scheme of application of preparations of alpha-lipoic (thioctic) acid. Recently in Europe and the United States conducted a series of clinical studies that have shown that the ...
A.V. Kaminsky
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Anticholesterol Activity of α-Lipoic Acid [PDF]
Nature, 1958 SINCE α-lipoic acid is known to affect lipid metabolism, we have investigated the effect of this acid on the lipid content of plasma, liver and aorta from rabbits which had been fed on a diet containing an excess of cholesterol1. Rabbits weighing 2.5–3 kgm. were divided into four groups, each containing five animals.
L, ANGELUCCI, E, MASCITELLI-CORIANDOLI
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Angewandte Chemie, EarlyView.We developed a novel domino polymerization to synthesize reductively degradable poly(disulfide)s with tunable side chains. A novel monomer bearing thiolactone and pyridyl disulfide groups reacts with various amines, enabling continuous ring‐opening and disulfide exchange.
Yukiya Kitayama +2 more
wiley +2 more sources
Journal of Diabetes Research, 2015 After evaluating the prevalence of early endothelial dysfunction, as measured by means of reactive hyperemia in adolescents with type 1 diabetes, we started a 6-month, double-blind, randomized trial to test the efficacy of an antioxidant diet (± alpha ...
Andrea Scaramuzza +8 more
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Advanced Functional Materials, EarlyView.This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann +2 more
wiley +1 more source
74 Alpha Lipoic Acid Responsive Hypergeusia [PDF]
CNS Spectrums, 2019 AbstractIntroductionImprovement in hypergeusia in response to alpha lipoic acid treatment has not heretofore been described. Such a case is presented.MethodsCase Study: A 64 year old right handed nasute female noted the sudden onset of salty hypergeusia, about 200% saltier than foods should be.
Sarah E. Cormie, Alan R. Hirsch
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Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Advanced Healthcare Materials, EarlyView.Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Current Issues in Molecular BiologyNatural products are widely used in the treatment of cancer due to the side effects of chemotherapeutics, and a large number of natural compounds have been reported to have anticancer activities in different types of cancer.
Ogunc Meral +9 more
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Mìžnarodnij Endokrinologìčnij Žurnal, 2012 The article deals with one of most common complications of diabetes mellitus — diabetic polyneuropathy. It is proved that alpha-lipoic acid is a drug of pathogenetic treatment of such pathology.
O.V. Bolshova, O.Ya. Samson
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