Results 21 to 30 of about 3,445,082 (289)
Dihydro-alpha-lipoic acid has more potent cytotoxicity than alpha-lipoic acid
In Vitro Cellular and Developmental Biology - Animal, 2009 Alpha-lipoic acid has been shown to possess cancer-cell-killing activity via activation of the apoptosis pathway. In this study, the cytotoxic activities of alpha-lipoic and dihydro-alpha-lipoic acid were compared in HL-60 cells. The cell-killing activity of dihydro-alpha-lipoic acid was higher than that of alpha-lipoic acid.
Masao Yamasaki +2 more
exaly +5 more sources
Alpha-lipoic acid drugs in the treatment of diabetic neuropathy
Медицинский совет, 2014 Diabetic neuropathy is the most common complication of diabetes mellitus. Among the large number of drugs used as symptomatic therapy to reduce its manifestations, alpha-lipoic acid medications are specific for providing pathogenic effect on many ...
L. Y. Morgunov
doaj +2 more sources
Synergistic antihyperglycemic effect of alpha lipoic acid with antidiabetic agents in the normoglycemic and streptozotocin-induced type 2 diabetic rats [PDF]
Acta Poloniae Pharmaceutica, 2023 The current study's main goal was to assess the supplementation effect of alpha lipoic acid with antidiabetic medications (metformin and sitagliptin) on normal and streptozotocin-induced blood glucose levels in normal and streptozotocin-induced diabetic ...
Rawsan Ali Sabri +2 more
doaj +1 more source
Revista Brasileira de Farmacognosia, 2023 Alpha-lipoic acid is an organic, sulfate-based compound produced by plants, humans, and animals. As a potent antioxidant and a natural dithiol compound, it performs a crucial role in mitochondrial bioenergetic reactions.
A. Tripathi +5 more
semanticscholar +1 more source
SVU-International Journal of Veterinary Sciences, 2022 Background: Pharmacological and toxicological challenges are among the most important studies in revealing the latent properties of drugs Objective: the goal of this study was to evaluate the effects of alpha-lipoic acid on the central nervous system ...
Marwa Abdul-Ghani, Ahmed Naser
doaj +1 more source
Endocrinology Research and Practice, 2021 Anti-insulin antibody syndrome is a rare autoimmune disorder that is characterized by severe hypoglycemia, elevated blood insulin level, insulin autoantibodies, and the absence of pancreas islet cell pathology or exogenous insulin exposure.
Emine KARTAL BAYKAN
doaj +1 more source
Nutrients, 2022 Alpha-lipoic acid (ALA) is a natural compound with antioxidant and pro-oxidant properties which has effects on the regulation of insulin sensitivity and insulin secretion.
Umberto Capece +10 more
semanticscholar +1 more source
Brazilian Journal of Otorhinolaryngology, 2023 Highlights • Alpha-lipoic acid is not better than olfactory training alone after COVID-19.• We found a strongly difference in baseline and endline olfaction in both groups.• This is the first trial comparing alpha-lipoic acid as an adjuvant treatment.
Lorena Pinheiro Figueiredo +4 more
semanticscholar +1 more source
Protective Potentials of Alpha-Lipoic Acid against Ionizing Radiation-Induced Brain Damage in Rats
Oxidative Medicine and Cellular Longevity, 2023 Background This study was aimed at determining the effects of alpha-lipoic acid on ionizing irradiation-induced oxidative damage and apoptosis in the brain of rats.
Ji Xu +6 more
semanticscholar +1 more source
Effect of Alpha-Lipoic Acid on the Characteristics and Physical Stability of NLC-Green Tea Extract
Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2022 Background: The addition of alpha-lipoic acid in Nanostructured Lipid Carrier-Green Tea Extract (NLC-GTE) has potential to increase effectiveness of anti-aging preparations.
Fairuz Yaumil Afra +2 more
doaj +1 more source