Diabetes and alpha lipoic acid [PDF]
Frontiers in Pharmacology, 2011 Diabetes mellitus is a multi-faceted metabolic disorder where there is increased oxidative stress that contributes to the pathogenesis of this debilitating disease.
Issy eLaher
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Neuroprotective Effects of Alpha Lipoic Acid on Haloperidol-Induced Oxidative Stress in the Rat Brain [PDF]
Cell & Bioscience, 2011 Haloperidol is an antipsychotic drug that exerts its' antipsychotic effects by inhibiting dopaminergic neurons. Although the exact pathophysiology of haloperidol extrapyramidal symptoms are not known, the role of reactive oxygen species in inducing ...
Perera Joachim +4 more
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Alpha-lipoic acid drugs in the treatment of diabetic neuropathy
Медицинский совет, 2014 Diabetic neuropathy is the most common complication of diabetes mellitus. Among the large number of drugs used as symptomatic therapy to reduce its manifestations, alpha-lipoic acid medications are specific for providing pathogenic effect on many ...
L. Y. Morgunov
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Effect of α-lipoic acid on the removal of arsenic from arsenic-loaded isolated liver tissues of rat [PDF]
Bangladesh Journal of Pharmacology, 2006 The patient of chronic arsenic toxicity shows oxidative stress. To overcome the oxidative stress, several antioxidants such as beta-carotene, ascorbic acid, alpha-tocopherol, zinc and selenium had been suggested in the treatment of chronic arsenic ...
Noor- E-Tabassum
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Alpha-Lipoic Acid and Diabetic Neuropathy [PDF]
The Review of Diabetic Studies, 2009 Diabetic neuropathy presents a major public health problem. It is defined by the symptoms and signs of peripheral nerve dysfunction in diabetic patients, in whom other causes of neuropathy have been excluded. Pathogenetic mechanisms that have been implicated in diabetic neuropathy are: a) increased flux through the polyol pathway, leading to ...
Natalia, Vallianou +2 more
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Attenuating Effect of Spirulina Platensis and Alpha-lipoic acid against Aspartame induced Oxidative stress and Brain damage in Rabbits [PDF]
Benha Veterinary Medical Journal, 2019 Spirulina and lipoic acid has been considered as one of the most effective in anti- oxidative stress and anti-inflammatory activity.Aspartame (ASP) is one of the mostwidely used (artificial sweeteners)used in a variety of foods and feeds.This study was ...
Mahamoud Arafa +3 more
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Protective Effects of Alpha Lipoic Acid Against Ionizing Radiation- Induced Hepatotoxicity in Rats
, 2023 Objective: Radiation is used to treat cancer but causes serious complications, such as liver toxicity. In this study, the protective effects of alpha lipoic acid against the unwanted effects of radiation used in many cancer treatments which can cause ...
Laloğlu, Abubekir +5 more
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Spirulina platensis and alpha lipoic acid are protective against the deleterious effects of aspartame on the liver and kidneys of rabbits [PDF]
Benha Veterinary Medical Journal, 2019 Spirulina platensis and alpha lipoic acid are the most important antioxidants. The purpose of this study was to explore the adverse effect of artificial sweetener (Aspartame) and the protective role of alpha lipoic acid and spirulina in alleviating the ...
Samy Hussein +3 more
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Alpha-Lipoic Acid for the Prevention of Diabetic Macular Edema [PDF]
, 2011 Introduction: To evaluate the effect of alpha-lipoic acid (ALA) on the occurrence of diabetic macular edema. Methods: Randomized, double-blind, placebo-controlled, multicenter, multinational study. Patients were randomized to the treatment group with 600
Haritoglou, Christos +10 more
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Apicoplast lipoic acid protein ligase B is not essential for Plasmodium falciparum [PDF]
, 2007 Lipoic acid (LA) is an essential cofactor of α-keto acid dehydrogenase complexes (KADHs) and the glycine cleavage system. In Plasmodium, LA is attached to the KADHs by organelle-specific lipoylation pathways.
Ryan Bissett +45 more
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