Alpha-lipoic acid reduces body weight and regulates triglycerides in obese patients with diabetes mellitus [PDF]
Medicinski Glasnik, 2015 Aim To determine an influence of alpha-lipoic acid to reduction of body weight and regulation of total cholesterol concentration, triglycerides and glucose serum levels in obese patients with diabetes mellitus type 2.
Azra Okanović +3 more
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Thermoregulatory and cardiovascular responses to creatine, glycerol and alpha lipoic acid in trained cyclists [PDF]
, 2012 Background It has been shown that supplementation with creatine (Cr) and glycerol (Gly), when combined with glucose (Glu) necessary for the enhancement of Cr uptake by skeletal muscle, induces significant improvements in thermoregulatory and ...
Hambly, C. +6 more
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Flurbiprofen: Determination of safety profile, analgesic effect, and interaction with lipoic acid in murine [PDF]
Iraqi Journal of Veterinary Sciences, 2023 our study aimed study aimed to detect and investigate the safety profile of flurbiprofen and evaluate the analgesic effects of the tail immersion and writhing tests, as well as its interaction with lipoic acid as an analgesic for visceral pain in mice ...
Naktal M. Alberifki, Ahmed S. Naser
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Protective role of vitamin B6 (PLP) against DNA damage in Drosophila models of type 2 diabetes [PDF]
, 2018 Growing evidence shows that improper intake of vitamin B6 increases cancer risk and several studies indicate that diabetic patients have a higher risk of developing tumors.
MF Fenech +69 more
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Dihydro-alpha-lipoic acid has more potent cytotoxicity than alpha-lipoic acid
In Vitro Cellular & Developmental Biology - Animal, 2009 Alpha-lipoic acid has been shown to possess cancer-cell-killing activity via activation of the apoptosis pathway. In this study, the cytotoxic activities of alpha-lipoic and dihydro-alpha-lipoic acid were compared in HL-60 cells. The cell-killing activity of dihydro-alpha-lipoic acid was higher than that of alpha-lipoic acid.
Masao, Yamasaki +9 more
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Alpha-Lipoic Acid for the Prevention of Diabetic Macular Edema [PDF]
, 2011 Introduction: To evaluate the effect of alpha-lipoic acid (ALA) on the occurrence of diabetic macular edema. Methods: Randomized, double-blind, placebo-controlled, multicenter, multinational study. Patients were randomized to the treatment group with 600
Anselm Kampik +5 more
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Gut microbiota markers in obese adolescent and adult patients: Age-dependent differential patterns [PDF]
, 2018 Obesity levels, especially in children, have dramatically increased over the last few decades. Recently, several studies highlighted the involvement of gut microbiota in the pathophysiology of obesity. We investigated the composition of gut microbiota in
Alessandra Russo +15 more
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Biochemical and clinical relevance of alpha lipoic acid: antioxidant and anti-inflammatory activity, molecular pathways and therapeutic potential [PDF]
, 2017 The molecular nature of lipoic acid (LA) clarifies its capability of taking part to a variety of biochemical reactions where redox state is meaningful.
Amenta, Francesco +9 more
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Drug Design, Development and Therapy, 2020 Giuseppe Derosa,1,2 Angela D’Angelo,2 Paola Preti,1 Pamela Maffioli1 1Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy; 2Laboratory of Molecular Medicine, University of Pavia, Pavia, ItalyCorrespondence: Giuseppe ...
Derosa G +3 more
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Efficacy of the R(+)-enantiomer of alpha-lipoic acid in clinical practice
Mìžnarodnij Endokrinologìčnij Žurnal, 2021 The article presents current data from the scientific medical literature on the effective use of the R(+)-enantiomer of α-lipoic acid in various pathological conditions.
N.О. Kravchun, I.P. Dunaieva
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