The Role of Oxidative Stress, Mitochondrial Function, and Autophagy in Diabetic Polyneuropathy
Journal of Diabetes Research, 2017 Diabetic polyneuropathy (DPN) is the most frequent and prevalent chronic complication of diabetes mellitus (DM). The state of persistent hyperglycemia leads to an increase in the production of cytosolic and mitochondrial reactive oxygen species (ROS) and
Sonia Sifuentes-Franco +3 more
semanticscholar +1 more source
Бюллетень сибирской медицины, 2012 Analysis of clinical and electroneuromyographic performance of two groups of patients with secondary polyneuropathy showed that diabetic neuropathy affects the peripheral nerves of the lower extremities, whereas in polyneuropathy of mixed etiology ...
Ye. S. Korolyova +3 more
doaj +1 more source
The assessment of diabetic polyneuropathy in daily clinical practice: Reproducibility and validity of Semmes Weinstein monofilaments examination and clinical neurological examination [PDF]
, 1997 Gerlof D. Valk +6 more
openalex +1 more source
Journal of Diabetes Research, 2016 Diabetic polyneuropathy (DPN) is defined as peripheral nerve dysfunction. There are three main alterations involved in the pathologic changes of DPN: inflammation, oxidative stress, and mitochondrial dysfunction.
L. M. Román-Pintos +4 more
semanticscholar +1 more source
Tropical Medicine &International Health, EarlyView.Abstract Background Orientia tsutsugamushi, the causative agent of scrub typhus, is increasingly recognised for its neurological complications. Among these, movement and gait disorders are poorly understood. We systematically examined their clinical spectrum and explored underlying mechanisms through in‐silico protein–protein interaction modelling ...
Ritwick Mondal +9 more
wiley +1 more source
Ophthalmic markers of the diabetic polyneuropathy
Ophthalmology Reports, 2016 In the article, a world literature analysis is presented on the relationship between structural and functional changes of the retina and of the optic nerve and the diabetic polyneuropathy severity degree. Diabetic polyneuropathy is one of the most common and severe complications of diabetes mellitus leading in many patients to ulcer formation and to ...
Mariia I Krasavina +3 more
openaire +2 more sources
Journal of Translational Medicine, 2017 Background Different lines of evidence suggest that oxidative stress (OS) is implicated in the pathogenesis of diabetic neuropathy. The Semmes–Weinstein monofilament (SWM) test is an efficient tool for evaluating diabetic polyneuropathy and diabetic foot.
Sergio Martinez-Hervás +7 more
doaj +1 more source
Methods for assessing diabetic polyneuropathy: validity and reproducibility of the measurement of sensory symptom severity and nerve function tests [PDF]
, 2000 Gerlof D. Valk +4 more
openalex +1 more source
Development of deep learning algorithms to categorize free-text notes pertaining to diabetes: convolution neural networks achieve higher accuracy than support vector machines [PDF]
arXiv, 2018 Health professionals can use natural language processing (NLP) technologies when reviewing electronic health records (EHR). Machine learning free-text classifiers can help them identify problems and make critical decisions. We aim to develop deep learning neural network algorithms that identify EHR progress notes pertaining to diabetes and validate the
arxiv
Painful and non‐painful diabetic polyneuropathy: Clinical characteristics and diagnostic issues
Journal of Diabetes Investigation, 2019 Diabetic neuropathy (DN) is a common complication of diabetes and can be either painful or non‐painful. It is challenging to diagnose this complication, as no biomarker or clear consensus on the clinical definition of either painful or non‐painful DN ...
S. S. Gylfadottir +5 more
semanticscholar +1 more source