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Diabetic Retinopathy: An Overview on Mechanisms, Pathophysiology and Pharmacotherapy
Diabetology, 2022 Diabetes mellitus is one of the most frequently occurring metabolic disorders (DMs), impairing healthy life around the globe, with mild-to-severe secondary complications. DM is associated with secondary complications, including diabetic retinopathy (DR),
Prawej Ansari +7 more
semanticscholar +1 more source
Journal of the American Medical Association (JAMA), 2016 Importance Deep learning is a family of computational methods that allow an algorithm to program itself by learning from a large set of examples that demonstrate the desired behavior, removing the need to specify rules explicitly.
Varun Gulshan +14 more
semanticscholar +1 more source
Mechanistic Pathogenesis of Endothelial Dysfunction in Diabetic Nephropathy and Retinopathy
Frontiers in Endocrinology, 2022 Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of diabetes. Microvascular endothelial cells are thought to be the major targets of hyperglycemic injury.
Jing Yang, Zhangsuo Liu
semanticscholar +1 more source
Postgraduate Medical Journal, 1984 Involvement of the retinal microvascular vessels is an almost inevitable consequence of long standing diabetes. In the only large scale epidemiology study of a Caucasian population Klein et al. found some degree of retinopathy in up to 97% of patients with insulin dependent diabetes mellitus (IDDM) after about 15 years diabetes duration and in about 60%
openaire +6 more sources
Global Prevalence and Major Risk Factors of Diabetic Retinopathy
Diabetes Care, 2012 OBJECTIVE To examine the global prevalence and major risk factors for diabetic retinopathy (DR) and vision-threatening diabetic retinopathy (VTDR) among people with diabetes. RESEARCH DESIGN AND METHODS A pooled analysis using individual participant data
J. Yau +35 more
semanticscholar +1 more source
MicroRNAs as biomarkers of diabetic retinopathy and disease progression
Neural Regeneration Research, 2019 Diabetes mellitus, together with its complications, has been increasing in prevalence worldwide. Its complications include cardiovascular disease (e.g., myocardial infarction, stroke), neuropathy, nephropathy, and eye complications (e.g., glaucoma ...
Bridget Martinez, Philip V Peplow
doaj +1 more source
JAMA Network Open, 2021 Key Points Question How does an artificial intelligence (AI) system for autonomous detection of vision-threatening diabetic retinopathy (vtDR) and more than mild diabetic retinopathy (mtmDR) compare with the reading center clinical reference standard ...
E. Ipp +12 more
semanticscholar +1 more source
Diabetic retinopathy detection and classification using capsule networks
Complex & Intelligent Systems, 2021 Nowadays, diabetic retinopathy is a prominent reason for blindness among the people who suffer from diabetes. Early and timely detection of this problem is critical for a good prognosis.
G. Kalyani +3 more
semanticscholar +1 more source
Journal of Clinical and Translational Science, 2018 OBJECTIVES/SPECIFIC AIMS: Diabetic retinopathy is the leading cause of blindness in adults aged 25–64 years. The prevalence of diabetic retinopathy is projected to increase 4-fold by 2050. Racial and ethnic minorities have a higher prevalence and greater
Kristen Nwanyanwu +3 more
doaj +1 more source
Is there any correlation between vitamin D insufficiency and diabetic retinopathy? [PDF]
International Journal of Ophthalmology, 2015 AIM: To determine a relation between vitamin D level, which is an inhibitor of angiogenesis, and diabetic retinopathy and its risk factors METHODS: In a clinic-based cross sectional study two hundred and thirty-five type 2 diabetic patients older than ...
Shokoufeh Bonakdaran , Nasser Shoeibi
doaj +1 more source