Results 31 to 40 of about 203,197 (289)

Inflammation in diabetic retinopathy: possible roles in pathogenesis and potential implications for therapy

Neural Regeneration Research, 2023
Diabetic retinopathy, characterized as a microangiopathy and neurodegenerative disease, is the leading cause of visual impairment in diabetic patients.
Lei Tang, Guo-Tong Xu, Jing-Fa Zhang
doaj   +1 more source

Rates of referable eye disease in the Scottish National Diabetic Retinopathy Screening Programme [PDF]

, 2014
Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.Peer reviewedPublisher ...
A D Morris, Cheng, D T Cromie, D W M Pearson, Elman, G P Leese, Ghafour, H C Looker, H M Colhoun, Hammes, J A McKnight, J A Olson, J Doig, Klein, Klein, Klein, Kohner, LeCaire, Leese, Leese, Looker, Looker, M W Black, Misra, Murgatroyd, N Lee, Olson, Pandit, Philip, R S Lindsay, Roy, S H Wild, S O Nyangoma, S Philip, Stratton, van Leiden, Zhang   +36 more
core   +7 more sources

Correlation of C-reactive protein and BMI with severity of diabetic retinopathy

Asian Journal of Medical Sciences, 2022
Background: Diabetic retinopathy is one of the complications of diabetes mellitus (DM). The pathogenesis has been attributed to be due to inflammation recently. Similarly, obesity has been found to be risk factor for diabetic retinopathy.
Naveen Nishal G , Renuga Devi Kaliaperumal , Nallamuthu P , Subhashini M   +3 more
doaj   +1 more source

Diabetic retinopathy: could the alpha-1 antitrypsin be a therapeutic option? [PDF]

, 2014
Diabetic retinopathy is one of the most important causes of blindness. The underlying mechanisms of this disease include inflammatory changes and remodeling processes of the extracellular-matrix (ECM) leading to pericyte and vascular endothelial cell ...
Chuluyan, Hector Eduardo, Gallo, Juan Eduardo Maria, Ortiz, Gustavo Alfredo, Salica, Juan Pablo   +3 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

A Smartphone-Based Tool for Rapid, Portable, and Automated Wide-Field Retinal Imaging. [PDF]

, 2018
Purpose:High-quality, wide-field retinal imaging is a valuable method for screening preventable, vision-threatening diseases of the retina. Smartphone-based retinal cameras hold promise for increasing access to retinal imaging, but variable image quality
Davila, Jose R, Echanique, Chris, Fletcher, Daniel A, Keenan, Jeremy, Kim, Tyson N, Li, Patrick, Loumou, Panagiota, Loury, PJ, Maamari, Robi N, Margolis, Todd, Myers, Frank, Paulus, Yannis M, Reber, Clay, Switz, Neil A, Webster, Doug, Woodward, Maria A   +15 more
core   +3 more sources

Pharmacological mydriasis in patients with type 2 diabetes. A comparative study among different levels of diabetic retinopathy [PDF]

Revista Brasileira de Oftalmologia
Objective: To analyze the diabetic autonomic neuropathy through the comparison between the pharmacological mydriasis in patients without diabetes and with type 2 diabetes. Methods: This is an observational, cross-sectional, case-control study.
Felipe Bekman Rocha, Nadyr Antonia Damasceno, Luziane Herzog de Azeredo Ramalho, Adroaldo de Alencar Costa Filho, Marcio Penha Morterá Rodrigues, Maria Luiza Gois da Fonseca, Raphael Boechat, Rubens Antunes da Cruz Filho, Eduardo de França Damasceno   +8 more
doaj   +1 more source

The Effect of Bariatric Surgery on Diabetic Retinopathy: Good, Bad, or Both? [PDF]

, 2016
Bariatric surgery, initially intended as a weight-loss procedure, is superior to standard lifestyle intervention and pharmacological therapy for type 2 diabetes in obese individuals.
Docherty, NG, Gorman, DM, Le Roux, CW
core   +3 more sources

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source