Results 31 to 40 of about 109,159 (253)

Autophagy Impairment in Retinal Ganglion Cells Following Hypoglycemia in Mice

Cells
(1) Background: Diabetic retinopathy (DR), caused by hypo- and hyperglycaemia, is the leading cause of blindness. Hypoglycemia induces endoplasmic reticulum stress and retinal cell death in mice, and low-glucose conditions induce macroautophagy/autophagy
Daria Fresia, Enrica Cannizzaro, Angelica Borgo, Marc Schwab, Raphaël Roduit   +4 more
doaj   +1 more source

Glycaemic status is an important risk factor for the occurrence of diabetic retinopathy in newly diagnosed type 2 diabetic patients

Asian Journal of Medical Sciences, 2015
Objective: To assess the frequency of diabetic retinopathy (DR) and correlation with HbA1C in newly diagnosed type 2 diabetic patients. Patients and research methods: The study was conducted at a tertiary care medical centre in north india.All ...
Sanjeev Kumar
doaj   +1 more source

Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park, Emily J. Koubek, Richard Beare, Lynn Ang, Brian C. Callaghan, Rodica Pop‐Busui, Eva L. Feldman, Evan L. Reynolds   +7 more
wiley   +1 more source

Multifunctional Catechol‐Functionalized Cellulose Hydrogels for the Minimally Invasive Treatment of Acute Optic Nerve Injuries

Advanced Healthcare Materials, EarlyView.
Catechol‐functionalized cellulose hydrogels are developed as injectable, bioadhesive platforms for retinal neuroprotection. The hydrogels exhibit tunable rheological and mechanical properties, strong tissue adhesion, and sustained antioxidative activity.
Kai‐Hsiang Chang, Yi‐Ke Lin, Wei‐Li Chen, Ta‐Ching Chen, Jiashing Yu   +4 more
wiley   +1 more source

Inflammation in diabetic retinopathy: possible roles in pathogenesis and potential implications for therapy

Neural Regeneration Research, 2023
Diabetic retinopathy, characterized as a microangiopathy and neurodegenerative disease, is the leading cause of visual impairment in diabetic patients.
Lei Tang, Guo-Tong Xu, Jing-Fa Zhang
doaj   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

Current epidemiology of diabetic retinopathy in patients with type 1 diabetes: a national multicenter study in Brazil

BMC Public Health, 2018
Background Diabetic retinopathy is the leading cause of blindness in economically active populations. The aims of this study were to estimate the prevalence and to identify risk factors for diabetic retinopathy in patients with type 1 diabetes in Brazil.
Laura Gomes Nunes Melo, Paulo Henrique Morales, Karla Rezende Guerra Drummond, Deborah Conte Santos, Marcela Haas Pizarro, Bianca Senger Vasconcelos Barros, Tessa Cerqueria Lemos Mattos, André Araújo Pinheiro, Felipe Mallmann, Franz Schubert Lopes Leal, Fernando Korn Malerbi, Marilia Brito Gomes   +11 more
doaj   +1 more source

Correlation of C-reactive protein and BMI with severity of diabetic retinopathy

Asian Journal of Medical Sciences, 2022
Background: Diabetic retinopathy is one of the complications of diabetes mellitus (DM). The pathogenesis has been attributed to be due to inflammation recently. Similarly, obesity has been found to be risk factor for diabetic retinopathy.
Naveen Nishal G , Renuga Devi Kaliaperumal , Nallamuthu P , Subhashini M   +3 more
doaj   +1 more source

Solid Harmonic Wavelet Bispectrum for Image Analysis

Advanced Science, EarlyView.
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown, Mathilda Avirett‐Mackenzie, Carolin Villforth, Georgios Exarchakis   +3 more
wiley   +1 more source

Pharmacological mydriasis in patients with type 2 diabetes. A comparative study among different levels of diabetic retinopathy [PDF]

Revista Brasileira de Oftalmologia
Objective: To analyze the diabetic autonomic neuropathy through the comparison between the pharmacological mydriasis in patients without diabetes and with type 2 diabetes. Methods: This is an observational, cross-sectional, case-control study.
Felipe Bekman Rocha, Nadyr Antonia Damasceno, Luziane Herzog de Azeredo Ramalho, Adroaldo de Alencar Costa Filho, Marcio Penha Morterá Rodrigues, Maria Luiza Gois da Fonseca, Raphael Boechat, Rubens Antunes da Cruz Filho, Eduardo de França Damasceno   +8 more
doaj   +1 more source