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Optical Biosensors for Blood Coagulation Monitoring: Advantages, Limitations, and Translational Potential [PDF]

Biosensors
Dynamic monitoring of hemostatic equilibrium is indispensable for clinical safety in high-risk scenarios, while current clinical methods are limited by sample volume, detection speed, and physiological relevance.
Zichen Wang, Gaohong Di, Jing Wang
doaj   +2 more sources

Edoxaban Dosing Time Affects Blood Coagulation Inhibition in Rats

TH Open, 2021
Coagulation–fibrinolytic system activity shows daily rhythmicity, with hypercoagulability in the morning and hypocoagulability in the evening. Consequently, the efficacy of anticoagulants may be influenced by their dosing time.
Naoto Nagata, Muneo Kawasumi, Akio Fujimura, Hitoshi Ando   +3 more
doaj   +1 more source

Intravitreal bevacizumab injection alone or combined with macular photocoagulation compared to macular photocoagulation as primary treatment of diabetic macular edema [PDF]

Vojnosanitetski Pregled, 2015
Background/Aim. Within diabetic retinopathy (DR), diabetic macular edema (DME) is one of the leading causes of the loss of visual acuity. The aim of this study was to determine the efficacy of the intravitreal vascular endothelial growth factor (
Jovanović Sandra, Čanadanović Vladimir, Sabo Ana, Grgić Zorka, Mitrović Milena, Rakić Dušan   +5 more
doaj   +1 more source

Transient simulation of laser ablation based on Monte Carlo light transport with dynamic optical properties model

Scientific Reports, 2023
Laser ablation is a minimally invasive therapeutic technique to denature tumors through coagulation and/or vaporization. Computational simulations of laser ablation can evaluate treatment outcomes quantitatively and provide numerical indices to determine
Yu Shimojo, Kazuma Sudo, Takahiro Nishimura, Toshiyuki Ozawa, Daisuke Tsuruta, Kunio Awazu   +5 more
doaj   +1 more source

Dysregulated coagulation system links to inflammation in diabetic kidney disease

Frontiers in Clinical Diabetes and Healthcare, 2023
Diabetic kidney disease (DKD) is a significant contributor to end-stage renal disease worldwide. Despite extensive research, the exact mechanisms responsible for its development remain incompletely understood. Notably, patients with diabetes and impaired
Mengyun Xiao, Donge Tang, Shaodong Luan, Bo Hu, Wenyu Gong, Wolfgang Pommer, Yong Dai, Lianghong Yin   +7 more
doaj   +1 more source

Blood Coagulation and Thrombotic Disorders following SARS-CoV-2 Infection and COVID-19 Vaccination

Biomedicines, 2023
Although abundant data confirm the efficacy and safety profile of the developed vaccines against COVID-19, there are still some concerns regarding vaccination in high-risk populations.
Metodija Sekulovski, Niya Mileva, Georgi Vasilev Vasilev, Dimitrina Miteva, Milena Gulinac, Monika Peshevska-Sekulovska, Lyubomir Chervenkov, Hristiana Batselova, Georgi Hristov Vasilev, Latchezar Tomov, Snezhina Lazova, Dobrin Vassilev, Tsvetelina Velikova   +12 more
doaj   +1 more source

Evaluation of coagulation factors in fresh frozen plasma treated with riboflavin and ultraviolet light [PDF]

Vojnosanitetski Pregled, 2012
Background/Aim. Pathogen inactivation in blood products using riboflavin and ultraviolet (UV) light represents a proactive approach to blood safety, not only for known infectious agents but also for new ones or not yet recognized as threats to the ...
Antić Ana, Stanojković Zoran, Mačukanović-Golubović Lana, Jelić Marija   +3 more
doaj   +1 more source

Preparation of Fe3O4@TiO2 blended PVDF membrane by magnetic coagulation bath and its permeability and pollution resistance

Journal of Materials Research and Technology, 2020
Fe3O4@TiO2 magnetic photocatalytic particles were synthesized and characterized. A composite PVDF separation membrane blended with Fe3O4@TiO2 particles was prepared by the phase inversion method.
Jian Sun, Shaofeng Li, Zhilin Ran, Yingxue Xiang   +3 more
doaj   +1 more source

Controlling Coagulation in Blood with Red Light [PDF]

Angewandte Chemie, 2021
AbstractPrecise control of blood clotting and rapid reversal of anticoagulation are essential in many clinical situations. We were successful in modifying a thrombin‐binding aptamer with a red‐light photocleavable linker derived from Cy7 by Cu‐catalyzed Click chemistry.
Patricia Müller, Marlen Sahlbach, Simone Gasper, Günter Mayer, Jens Müller, Bernd Pötzsch, Alexander Heckel   +6 more
openaire   +5 more sources

Intense light as anticoagulant therapy in humans.

PLoS ONE, 2020
Blood coagulation is central to myocardial ischemia and reperfusion (IR) injury. Studies on the light elicited circadian rhythm protein Period 2 (PER2) using whole body Per2-/- mice found deficient platelet function and reduced clotting which would be ...
Yoshimasa Oyama, Sydney Shuff, Pavel Davizon-Castillo, Nathan Clendenen, Tobias Eckle   +4 more
doaj   +1 more source