Results 1 to 10 of about 384,973 (266)

DOAC‐Stop in lupus anticoagulant testing: Direct oral anticoagulant interference removed in most samples

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2021
Background The use of direct oral anticoagulants (DOACs) is a convenient therapeutic option for patients at risk of thrombosis. DOACs interfere with clot‐based testing for the identification of lupus anticoagulant antibodies (LACs) in patients with ...
Steven Andrew Baker   +4 more
doaj   +1 more source

Impaired platelet function in Hermansky-Pudlak syndrome associated with novel mutations in HPS3, HPS6 and HPS8 genes

open access: yesBleeding, Thrombosis and Vascular Biology
We report three unrelated cases of Hermansky-Pudlak (HP) characterized by novel mutations in HPS3 (compound heterozygosity for c.1457G>A and c.1813G>T), HPS6 (homozygous c.210_211insGGGCC), and HPS8 (homozygous c.299dupC in BLOC1S3) genes.
Lisa Pieri   +4 more
doaj   +1 more source

Diabetes Mellitus and Cardiovascular Prevention: The Role and the Limitations of Currently Available Antiplatelet Drugs

open access: yesInternational Journal of Vascular Medicine, 2011
Diabetes mellitus (DM) is associated with macrovascular and microvascular complications. Platelets have a “key role” in atherogenesis and its thrombotic complications in subjects with DM.
A. Tufano   +7 more
doaj   +1 more source

Catalytic coagulation

open access: yesPhysical Review E
We introduce an autocatalytic aggregation model in which the rate at which two clusters merge to form a cluster is controlled by the presence of a third "catalytic" cluster whose mass must equal to the mass of one of the reaction partners. The catalyst is unaffected by the joining event and is available to either participate in or catalyze subsequent ...
P. L. Krapivsky, S. Redner
openaire   +3 more sources

Gene transfer in hemophilia B: a big step forward

open access: yesBleeding, Thrombosis and Vascular Biology, 2023
Not ...
Giancarlo Castaman
doaj   +3 more sources

Acute Myeloid Leukemia With NPM1 Mutation Presenting With Rapidly Progressing Hypereosinophilia

open access: yesCase Reports in Hematology
Hypereosinophilia presents a significant clinical challenge. We describe a case of severe, rapidly progressing hypereosinophilia, with the white blood cell count increasing from 40,000/μL to over 130,000/μL within days, and 70% eosinophils on ...
S. Einarsdottir   +4 more
doaj   +1 more source

Translation and Cultural Adaptation of the ISTH-Bleeding Assessment Tool to European Portuguese

open access: yesActa Médica Portuguesa
Introduction: A distinctive bleeding history is the first diagnostic stage of congenital hemorrhagic diseases. Furthermore, since it is in fact an assessment of the patient’s phenotype, it is not a (mere) complementary diagnostic method or test - it is ...
Diana Carneiro-Leão   +6 more
doaj   +1 more source

Thiazole orange: a complement to established methods for diagnosing inherited dense granule defects

open access: yesPlatelets
Inherited delta storage pool deficiencies are likely underdiagnosed due to limitations in available diagnostic tools. Achieving accurate diagnosis is thus challenging for clinical laboratories highlighting the need for improved methods.
Myriam Martin   +3 more
doaj   +1 more source

To coagulate or not to coagulate. That is the question

open access: yes, 2021
Decision-making is a complex issue especially in severe multi-pathological patients, whose processes interact with each other and with other treatments, making it impossible to follow regular protocols. In this case, the patient suffered from a cranioencephalic traumatism and a pulmonary thromboembolism.
de Mota Dengra, Elena   +2 more
openaire   +1 more source

A clinical survey of bleeding, thrombosis, and blood product use in decompensated cirrhosis patients

open access: yesAnnals of Hepatology, 2012
Background. The relative incidence of bleeding and thrombotic events and the use of blood products in hospitalized cirrhosis patients have not been widely reported.
Neeral L. Shah   +2 more
doaj   +1 more source

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