Results 21 to 30 of about 522,194 (294)

Failure of Fondaparinux in Autoimmune Heparin-Induced Thrombocytopenia

TH Open, 2020
Heparin-induced thrombocytopenia (HIT) is an immune adverse reaction to heparin that is associated with life-threatening thrombotic complications.
Michelangelo Sartori, Benilde Cosmi
doaj   +1 more source

Coagulation

Journal of the Royal College of Physicians of Edinburgh, 2014
The haemostatic system comprises four compartments: the vasculature, platelets, coagulation factors, and the fibrinolytic system. There is presently no laboratory or near-patient test capable of reproducing the complex regulated interaction between these four compartments.
openaire   +2 more sources

Efficacy, safety and surgical management with concizumab prophylaxis in three young patients affected by severe hemophilia with inhibitors

Bleeding, Thrombosis and Vascular Biology
Background: concizumab is an anti-tissue factor inhibitor monoclonal antibody designed as a once-daily subcutaneous prophylactic treatment for all hemophilia patients.
Silvia Linari, Lisa Pieri, Raffaella Pasquino, Eleonora Piellucci, Monica Attanasio, Francesca Salvianti, Giancarlo Castaman   +6 more
doaj   +1 more source

Mesoglycan: Clinical Evidences for Use in Vascular Diseases

International Journal of Vascular Medicine, 2010
Vascular glycosaminoglycans (GAG) are essential components of the endothelium and vessel wall and have been shown to be involved in several biologic functions.
Antonella Tufano, Claudia Arturo, Ernesto Cimino, Matteo Nicola Dario Di Minno, Mirko Di Capua, Anna Maria Cerbone, Giovanni Di Minno   +6 more
doaj   +1 more source

AAQRL/hybrid-ANN-coagulation-model: version 1.0.0

, 2023
Full Changelog: https://github.com/AAQRL/hybrid-ANN-coagulation-model/commits/v1.0.
AAQRL
core   +1 more source

Coagulation-related factors and outcome groups of the study patients.

, 2023
The medians with interquartile ranges (box) and 10th-90th percentiles (whiskers) are presented. A represents coagulation-related factors between admission and 24 hours after ROSC.
Jung Hee Wee (6091004), Joo Suk Oh (6090998), Won Young Kim (8218422), Mi Jin Lee (1535512), Kurz Michael (14341606), Yong Hwan Kim (411929), In Soo Cho (6090995), Hyo Joon Kim (9449656), Dong Hun Lee (533726), Chun Song Youn (6091010)   +9 more
core   +1 more source

Tumour-associated Mucin1 correlates with the procoagulant properties of cancer cells of epithelial origin

Thrombosis Update, 2022
Background: Cancer-associated thrombosis (CAT) is caused, at least in part, by procoagulant factors produced by the tumour itself. Although MUC1 is an established biomarker for the diagnosis, immunotherapy, and prognosis of cancer, it is unclear whether ...
Yunliang Chen, Michael Scully
doaj   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Impaired platelet function in Hermansky-Pudlak syndrome associated with novel mutations in HPS3, HPS6 and HPS8 genes

Bleeding, Thrombosis and Vascular Biology
We report three unrelated cases of Hermansky-Pudlak (HP) characterized by novel mutations in HPS3 (compound heterozygosity for c.1457G>A and c.1813G>T), HPS6 (homozygous c.210_211insGGGCC), and HPS8 (homozygous c.299dupC in BLOC1S3) genes.
Lisa Pieri, Silvia Linari, Francesca Salvianti, Monica Attanasio, Giancarlo Castaman   +4 more
doaj   +1 more source

Diabetes Mellitus and Cardiovascular Prevention: The Role and the Limitations of Currently Available Antiplatelet Drugs

International Journal of Vascular Medicine, 2011
Diabetes mellitus (DM) is associated with macrovascular and microvascular complications. Platelets have a “key role” in atherogenesis and its thrombotic complications in subjects with DM.
A. Tufano, E. Cimino, M. N. D. Di Minno, P. Ieranò, E. Marrone, A. Strazzullo, G. Di Minno, A. M. Cerbone   +7 more
doaj   +1 more source