Results 91 to 100 of about 747,888 (257)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Dual diagnosis competencies: A systematic review of staff training literature

open access: yesAddictive Behaviors Reports, 2018
Objective: To conduct a systematic review of the literature regarding approaches to staff training in dual diagnosis competencies. Methods: A search was conducted using eight databases: Informit, Taylor & Francis, Springer, Proquest, Expand, Sage, Psych ...
Melissa Petrakis   +4 more
doaj   +1 more source

Improving the cost effectiveness equation of cascade testing for Familial Hypercholesterolaemia (FH) [PDF]

open access: yes, 2015
Purpose of Review : Many International recommendations for the management of Familial Hypercholesterolaemia (FH) propose the use of Cascade Testing (CT) using the family mutation to unambiguously identify affected relatives.
Futema, M   +3 more
core  

An introduction to local Black Hole horizons in the 3+1 approach to General Relativity

open access: yes, 2011
We present an introduction to dynamical trapping horizons as quasi-local models for black hole horizons, from the perspective of an Initial Value Problem approach to the construction of generic black hole spacetimes.
Ashtekar A.   +10 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Prevalence of dual diagnosis in the south of Peru: descriptive clinical study

open access: yesInteracciones, 2016
Comorbidity between substance use disorders and other psychiatric disorders or dual diagnosis (PD) is characterized by difficulty in their therapeutic approach, constant relapses and hospital admissions, as well as higher violent and criminal behavior ...
Jonathan A. Zegarra-Valdivia   +2 more
doaj   +1 more source

TandemNet: Distilling Knowledge from Medical Images Using Diagnostic Reports as Optional Semantic References

open access: yes, 2017
In this paper, we introduce the semantic knowledge of medical images from their diagnostic reports to provide an inspirational network training and an interpretable prediction mechanism with our proposed novel multimodal neural network, namely TandemNet.
G Huang   +4 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Advanced parametric imaging for evaluation of Crohn's disease using dual-energy computed tomography enterography

open access: yesRadiology Case Reports, 2018
We describe a case of small bowel Crohn's disease in which dual-energy computed tomography enterography using dual-layer spectral detector scanner contributed to quantitative assessment, and provided a higher degree of confidence pertaining to the ...
Narumi Taguchi, MD   +7 more
doaj   +1 more source

Digital mammography, cancer screening: Factors important for image compression [PDF]

open access: yes
The use of digital mammography for breast cancer screening poses several novel problems such as development of digital sensors, computer assisted diagnosis (CAD) methods for image noise suppression, enhancement, and pattern recognition, compression ...
Blaine, G. James   +7 more
core   +1 more source

Home - About - Disclaimer - Privacy