Results 61 to 70 of about 747,888 (257)

What kind of science for dual diagnosis? A pragmatic examination of the enactive approach to psychiatry

Frontiers in Psychology, 2022
The recommended treatment for dual diagnosis - the co-occurrence of substance use and another mental disorder - requires seamless integration of the involved disciplines and services.
Jonathan Led Larsen, Jonathan Led Larsen, Katrine Schepelern Johansen, Mimi Yung Mehlsen   +3 more
doaj   +1 more source

Substance misuse assessment in mental health services: the importance of professional curiosity [PDF]

, 2017
Co-morbidity of mental health and substance misuse problems (or "Dual Diagnosis") is highly prevalent in mental health and drug treatment services. The parallel approach, where the two conditions are treated at the same time in separate services, is the ...
Milani, Raffaella Margherita, University of West London   +1 more
core  

The diagnostic accuracy of two human epididymis protein 4 (HE4) testing systems in combination with CA125 in the differential diagnosis of ovarian masses [PDF]

, 2011
Background: Cancer antigen 125 (CA125) is the best known single tumor marker for ovarian cancer (OC). We investigated whether the additional information of the human epididymis protein 4 (HE4) improves diagnostic accuracy.
Burges, Alexander, Fuerst, Sophie, Hertlein, Linda, Hofmann, Karin, Kirschenhofer, Angela, Krocker, Katja, Lenhard, Miriam, Mayr, Doris, Nagel, Dorothea, Stieber, Petra   +9 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Treating Dual Diagnosis Patients: Challenges and Opportunities [PDF]

, 2011
The use and abuse of drugs and alcohol have recently gained greater attention both from the public and the medical profession. Despite increasing cognizance of its unfortunate consequences, substance use has become a more pervasive element of ...
Howland, M.D., Robert H.
core   +1 more source

Beam hardening artifact reduction using dual energy computed tomography: implications for myocardial perfusion studies [PDF]

, 2015
Background: Myocardial perfusion computed tomography (CTP) using conventional single energy (SE) imaging is influenced by the presence of beam hardening artifacts (BHA), occasionally resembling perfusion defects and commonly observed at the left ...
Capunay, Carlos, Carrascosa, Patricia, Cipriano, Silvia, Cury, Ricardo C., De Zan, Macarena, Deviggiano, Alejandro, Rodriguez Granillo, Gaston Alfredo   +6 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

The relationship between personality dimensions and addiction type in women addicted to alcohol and opioids

Scientific Reports
Personality traits significantly influence the development, persistence, and treatment outcomes of substance use disorders. Despite increasing addiction rates among women, sex-specific research remains limited.
Diana Raketić, Nikola Lalović, Jasmina Barišić, Ivan Ćelić, Srdjan Milovanović   +4 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Reduction of radiation dose for coronary computed tomography angiography using prospective electrocardiography-triggered high-pitch acquisition in clinical routine [PDF]

, 2018
Purpose: To evaluate the image quality, radiation exposure, and means of application in a group of patients who underwent coronary computed tomography angiography (CCTA) performed with low-dose prospective electrocardiography (ECG)-triggered acquisition ...
Chaosuwannakit, Narumol, Makarawate, Pattarapong   +1 more
core   +1 more source