Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia +20 more
wiley +1 more source
Hiding in Plain Sight: Pulmonary Vein Stenosis Following Pediatric Heart Transplantation. [PDF]
O'Halloran CP +3 more
europepmc +1 more source
The Historical Development and Relative Value of Laboratory and Clinical Methods of Diagnosis [PDF]
Richard C. Cabot
openalex +1 more source
Multimodal Autonomic Biomarkers Predict Phenoconversion in Pure Autonomic Failure
ABSTRACT Background Pure autonomic failure (PAF) presents with autonomic failure without other neurological features. A third develop central neurological features, fulfilling criteria for multiple system atrophy (MSA) and Lewy body diseases (LBD), including Parkinson's disease and Dementia with Lewy bodies.
S. Koay +12 more
wiley +1 more source
Clinical Practice Guidelines for the Diagnosis of Inflammatory Bowel Disease (IBD): A Scoping Review. [PDF]
Doyle C +5 more
europepmc +1 more source
Utilization of Laboratory Findings in Diagnosis and Control of Hospital Staphylococcal Infections
J A Bass, Harriet M. Felton
openalex +1 more source
ABSTRACT Objective To identify metabolic patterns in the brain and musculoskeletal system of stiff person syndrome spectrum disorders (SPSD) patients over time using PET imaging and evaluate the impact of immune therapy on metabolic activity as a surrogate for treatment response.
Munther M. Queisi +4 more
wiley +1 more source
Role of PCPs in diagnosing dementia in traditional Medicare and Medicare Advantage. [PDF]
Haye S, Jacobson M, Zissimopoulos J.
europepmc +1 more source
THE DIAGNOSIS AND TREATMENT OF "LATE" HEREDITARY SYPHILIS [PDF]
Borden S. Veeder
openalex +1 more source
NOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics
ABSTRACT Objective Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by NOTCH2NLC GGC repeat expansions, with heterogeneous clinical manifestations, including parkinsonism. Recent studies have identified NOTCH2NLC repeat expansions in patients with Parkinson's disease (PD) and atypical parkinsonism (aPM), suggesting ...
Han‐Lin Chiang +7 more
wiley +1 more source

