Results 81 to 90 of about 12,810,150 (402)

Prenatal diagnosis and genetic etiology analysis of talipes equinovarus by chromosomal microarray analysis

BMC Medical Genomics, 2023
Background With the advancement of molecular technology, fetal talipes equinovarus (TE) is believed to be not only associated with chromosome aneuploidy, but also related to chromosomal microdeletion and microduplication.
Xiaorui Xie, Baojia Huang, Linjuan Su, Meiying Cai, Yuqin Chen, Xiaoqing Wu, Liangpu Xu   +6 more
doaj   +1 more source

Analyzing the Triad Diagnosis Requirement for Autism in Arkansas [PDF]

, 2020
Autism Spectrum Disorder (ASD) is a developmental disorder that has steadily increased in incidence and prevalence over the last ten years. While the disorder can be diagnosed as early as two years of age, most children do not receive a diagnosis until ...
Barrientos-Figueroa, Liliana
core   +2 more sources

Characteristics of people living in Italy after a cancer diagnosis in 2010 and projections to 2020 [PDF]

, 2018
BACKGROUND: Estimates of cancer prevalence are widely based on limited duration, often including patients living after a cancer diagnosis made in the previous 5 years and less frequently on complete prevalence (i.e., including all patients regardless of
Botta, Laura, Buzzoni, Carlotta, Caiazzo, Anna Luisa, Candela, Giuseppa, Capocaccia, Riccardo, Caruso, Bianca, Casella, Claudia, Castaing, Marine, De Angelis, Roberta, Falcini, Fabio, Fanetti, Anna Clara, Ferretti, Stefano, Francisci, Silvia, Fusco, Mario, Giacomin, Adriano, Gigli, Anna, Gola, Gemma, Guzzinati, Stefano, Mangone, Lucia, Maso, Luigino Dal, Mazzoleni, Guido, Michiara, Maria, Pala, Filomena, Panato, Chiara, Pannozzo, Fabio, Ricci, Paolo, Rudisi, Giuseppa, Rugge, Massimo, Russo, Antonio Giampiero, Sardo, Antonella Sutera, Sensi, Flavio, Serraino, Diego, Stracci, Fabrizio, Tagliabue, Giovanna, Tisano, Francesco, Tumino, Rosario, Virdone, Saverio, Zorzi, Manuel   +37 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Benign prostatic hyperplasia : Part 1- diagnosis [PDF]

, 2008
Peer reviewedPublisher ...
N'Dow, James Michael Olu, Wilt, Timothy
core   +2 more sources

Artificial Neural Networks in Medical Diagnosis

International Journal of Research Publication and Reviews
Artificial neural networks are finding many uses in the medical diagnosis application. The goal of this paper is to evaluate artificial neural network in disease diagnosis. Two cases are studied.
Qeethara Al-Shayea
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Fusions of Tumor-derived Endothelial Cells with Dendritic Cells Induces Antitumor Immunity

Scientific Reports, 2017
To explore dendritic cells/tumor-derived endothelial cells (DC/EC) fusion cells are potent stimulators of T cells to impact tumor progression. ECs were isolated from mice hepatoma cell line (H22) Xenograft, and dendritic cells were isolated from bone ...
Yingying Huang, Qiqi Mao, Jian He, Jing Su, Yi Peng, Wei Liang, Zixi Hu, Sufang Zhou, Xiaoling Lu, Yongxiang Zhao   +9 more
doaj   +1 more source

Intranasal melanoma treated with radiation therapy in three dogs [PDF]

, 2017
Three dogs were investigated for chronic unilateral nasal discharge. In all cases CT imaging showed an intranasal mass causing turbinate lysis and no evidence of metastasis.
Blackwood, L, Davies, O, Holmes, E, Lara-Garcia, A, Necova, S, Spencer, S, Taylor, A   +6 more
core   +3 more sources