Results 1 to 10 of about 5,058,925 (316)

Expert consensus on diagnosis, treatment and fertility management of young breast cancer patients

Journal of the National Cancer Center, 2021
Breast cancer in young females is a relatively common disease in China. Young breast cancer has aggressive clinical and pathological features. During the treatment of young females with breast cancer, issues involving the choice of surgical methods ...
Committee of Diagnosis, Treatment, and Fertility Management of Chinese Young Breast Cancer Patients
doaj   +1 more source

Guidelines for the Multidisciplinary Diagnosis and Treatment of Neurofibromatosis Type 1(2023 Version)

罕见病研究, 2023
Neurofibromatosis type 1(NF1) is an autosomal dominant hereditary neoplastic disease caused by mutations in the NF1 gene. Features of disorder typically appear in early childhood.
Multidisciplinary Diagnosis and Treatment Collaboration Group for Neurofibromatosis Type 1 of China Alliance for Rare Diseases
doaj   +1 more source

China National Lung Cancer Screening Guideline with Low-dose Computed Tomography (2023 Version)

Chinese Journal of Lung Cancer, 2023
Lung cancer is the leading cause of cancer-related death in China. The effectiveness of low-dose computed tomography (LDCT) screening has been further validated in recent years, and significant progress has been made in research on identifying high-risk ...
Chinese Expert Group on Early Diagnosis and Treatment of Lung Cancer, China Lung Oncology Group   +1 more
doaj   +1 more source

TNF-α Enhances the Therapeutic Effects of MenSC-Derived Small Extracellular Vesicles on Inflammatory Bowel Disease through Macrophage Polarization by miR-24-3p

Stem Cells International, 2023
Human menstrual blood-derived mesenchymal stem cells (MenSCs) and their secreted small extracellular vesicles (EVs) had been proven to relieve inflammation, tissue damage, and fibrosis in various organs.
Huikang Xu, Jiamin Fu, Lijun Chen, Sining Zhou, Yangxin Fang, Qi Zhang, Xin Chen, Li Yuan, Yifei Li, Zhenyu Xu, Charlie Xiang   +10 more
doaj   +1 more source

DNA damage, demethylation and anticancer activity of DNA methyltransferase (DNMT) inhibitors

Scientific Reports, 2023
Role of DNA damage and demethylation on anticancer activity of DNA methyltransferase inhibitors (DNMTi) remains undefined. We report the effects of DNMT1 gene deletion/disruption (DNMT1 −/− ) on anticancer activity of a class of DNMTi in vitro, in vivo ...
Angelo B. A. Laranjeira, Melinda G. Hollingshead, Dat Nguyen, Robert J. Kinders, James H. Doroshow, Sherry X. Yang   +5 more
doaj   +1 more source

Hirsutism: diagnosis and treatment [PDF]

Arquivos Brasileiros de Endocrinologia & Metabologia, 2014
Hirsutism is defined as excessive terminal hair growth in androgen-dependent areas of the body in women, which grows in a typical male distribution pattern. Hirsutism is a common clinical problem in women, and the treatment depends on the cause. The condition is often associated with a loss of self-esteem.
Hohl, Alexandre, Ronsoni, Marcelo Fernando, Oliveira, Mônica de   +2 more
openaire   +4 more sources

Scabies: diagnosis and treatment [PDF]

BMJ, 2005
Scabies is an intensely itchy dermatosis caused by the mite Sarcoptes scabiei . A patient with ordinary scabies may have an average of 12 mites; however, those with crusted scabies may have thousands of mites. The infestation occurs at all ages, but particularly in children.
Graham, Johnston, Mike, Sladden
openaire   +2 more sources

Mitochondrial Mechanisms of Apoptosis and Necroptosis in Liver Diseases

Analytical Cellular Pathology, 2021
In addition to playing a pivotal role in cellular energetics and biosynthesis, mitochondrial components are key operators in the regulation of cell death.
Qingfei Chu, Xinyu Gu, Qiuxian Zheng, Jing Wang, Haihong Zhu   +4 more
doaj   +1 more source

Overexpression of HOTAIR leads to radioresistance of human cervical cancer via promoting HIF-1α expression

Radiation Oncology, 2018
Background HOTAIR was known to enhance radioresistance in several cancers. However, the function of HOTAIR on radioresistance involving the regulation of HIF-1α in cervical cancer has not been reported.
Ning Li, Dan-dan Meng, Ling Gao, Yue Xu, Pei-jie Liu, Yong-wei Tian, Zhen-ying Yi, Yan Zhang, Xiao-jing Tie, Zhi-qiao Xu   +9 more
doaj   +1 more source

CO2 or air cholangiography reduces the risk of post-ERCP cholangitis in patients with Bismuth type IV hilar biliary obstruction

BMC Gastroenterology, 2020
Background Endoscopic biliary stenting by endoscopic retrograde cholangiopancreatography (ERCP) is the most common form of palliation for malignant hilar obstruction. However, ERCP in such cases is associated with a risk of cholangitis.
Wen-hui Zhang, Peng-peng Ding, Lei Liu, Yan-ling Wang, Wen-hui Lai, Jing-jing Han, Jun Han, Han-wei Li   +7 more
doaj   +1 more source