Results 91 to 100 of about 5,165,384 (312)

Genome-wide DNA methylation and hydroxymethylation analysis reveal human menstrual blood-derived stem cells inhibit hepatocellular carcinoma growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements

Stem Cell Research & Therapy, 2019
Background Epigenetic alteration is an important indicator of crosstalk between cancer cells and surrounding microenvironment components including mesenchymal stem cells (MSC).
Yichen Wu, Xin Chen, Yongjia Zhao, Yanling Wang, Yifei Li, Charlie Xiang   +5 more
doaj   +1 more source

Disease burden of chronic hepatitis B and complications in China from 2006 to 2050: an individual-based modeling study

Virology Journal, 2020
Background Chronic hepatitis B has become a major public health problem in China. An accurate depiction of the disease burden has not yet been thoroughly conducted.
Yang Zheng, Jie Wu, Cheng Ding, Kaijin Xu, Shigui Yang, Lanjuan Li   +5 more
doaj   +1 more source

Autoimmune diseases and their manifestations on oral cavity: diagnosis and clinical management [PDF]

, 2018
Oral signs are frequently the first manifestation of autoimmune diseases. For this reason, dentists play an important role in the detection of emerging autoimmune pathologies.
Bossù, Maurizio, Di Carlo, Gabriele, Giovarruscio, Francesca, Polimeni, Antonella, Saccucci, Matteo, Salucci, Alessandro   +5 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Mortality risk of patients with intestinal obstruction

BMC Cancer
Background Intestinal obstruction represents a severe intestinal disease associated with higher mortality rates. However, the determinants of mortality in patients with intestinal obstruction remain inadequately understood. This study sought to elucidate
Yuanyuan Wang, Wei Li, Chuan-min Zhou, Zifeng Zhao, Jianwei Ma, Haibo Jiang, Ming Wei, Yingchao Gao, Yongjun Dai, Xing Zhang, Ning Yang, Feng Feng, Jian Zhang, Yiding Ji, Jianjie Liu, Chao Zhang, Like Li, Xia Jiang, Zhongxin Li, Zengren Zhao   +19 more
doaj   +1 more source

Human cytomegalovirus and Epstein-Barr virus infections, risk factors, and their influence on the liver function of patients with acute-on-chronic liver failure

BMC Infectious Diseases, 2018
Background Studies on human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) have focused primarily on the immunosuppressed population. Few studies have considered immunocompetent and not severely immunocompromised patients.
Jianhua Hu, Hong Zhao, Danfeng Lou, Hainv Gao, Meifang Yang, Xuan Zhang, Hongyu Jia, Lanjuan Li   +7 more
doaj   +1 more source

Predictors of Physical Therapy Non-Treatment Among Patients Scheduled for Treatment Two Times a Day in the Acute Hospital

, 2017
Background and Purpose: Consistent participation in physical therapy treatment is the key to the success of any physical therapy treatment program. Scheduled therapy sessions that do not result in treatment (non-treatment) may cause longer hospital stays
Bookout, Sara, Ozaki, Kyle
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Economic inequalities in burden of illness, diagnosis and treatment of five long-term conditions in England: panel study [PDF]

, 2014
We compared the distribution by wealth of self-reported illness burden (estimated from validated scales, biomarker and reported symptoms) for angina, cataract, depression, diabetes and osteoarthritis, with the distribution of self-reported medical ...
Bachmann, M. O., Campbell, J., Clark, A., Hardcastle, A. C., Lang, I., Melzer, D., Mounce, L. T. A., Richards, S. H., Steel, N.   +8 more
core   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source